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CRISPR and Genetic Engineering Sign in to save
Papers per year
Papers 122
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Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing2020 Nature Cell Biology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Benedetta Artegiani, Delilah F. G. Hendriks, Joep Beumer, Rutger N.U. Kok, Xuan Zheng, Indi P. Joore, +4 more
300citations -
CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations2022 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ida Höijer, Anastasia Emmanouilidou, Rebecka Östlund, Robin van Schendel, Selma Bozorgpana, Marcel Tijsterman, +4 more
196citations -
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea2020 PLoS Pathogens article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Thomas Leisen, Fabian Bietz, J.A. Werner, Alex Wegner, Ulrich Schaffrath, David Scheuring, +4 more
128citations -
Alternative functions of CRISPR–Cas systems in the evolutionary arms race2022 Nature Reviews Microbiology review Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Prarthana Mohanraju, Chinmoy Kumar Saha, Peter van Baarlen, Rogier Louwen, Raymond H.J. Staals, John van der OOST
89citations -
Modulating mutational outcomes and improving precise gene editing at CRISPR-Cas9-induced breaks by chemical inhibition of end-joining pathways2023 Cell Reports article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Joost Schimmel, Núria Muñoz-Subirana, Hanneke Kool, Robin van Schendel, Sven van der Vlies, Juliette A. Kamp, +5 more
80citations -
Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group2025 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Alessia Cavazza, Francisco Javier Molina-Estévez, Álvaro Plaza Reyes, Victor Ronco, Asma Naseem, Špela Malenšek, +30 more
66citations -
Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components2020 Gene Therapy article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ignazio Maggio, Hidde A. Zittersteijn, Qian Wang, Jin Liu, Josephine M. Janssen, Ivan Toral Ojeda, +4 more
66citations -
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids2023 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Maarten H. Geurts, Shashank Gandhi, Matteo Boretto, Ninouk Akkerman, Lucca L. M. Derks, Gijs J. F. van Son, +10 more
65citations -
STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells2022 Cell Reports Methods article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Albert Blanch-Asensio, Catarina Grandela, Karina O. Brandão, Tessa de Korte, Hailiang Mei, Yavuz Ariyürek, +6 more
55citations -
Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery2021 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Qian Wang, Jin Liu, Josephine M. Janssen, Francesca Tasca, Hailiang Mei, Manuel A.F.V. Gonçalves
45citations -
Precise and broad scope genome editing based on high-specificity Cas9 nickases2020 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Qian Wang, Jin Liu, Josephine M. Janssen, Marie Le Bouteiller, Richard L. Frock, Manuel A.F.V. Gonçalves
39citations -
Preservation stress resistance of melanin deficient conidia from Paecilomyces variotii and Penicillium roqueforti mutants generated via CRISPR/Cas9 genome editing2021 Fungal Biology and Biotechnology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Sjoerd J. Seekles, Pepijn Teunisse, Maarten Punt, Tom van den Brule, Jan Dijksterhuis, Jos A. M. P. Houbraken, +2 more
35citations -
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Benedetta Artegiani, Delilah F. G. Hendriks, Joep Beumer, Rutger N.U. Kok, Xuan Zheng, Indi P. Joore, +4 more
29citations -
Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy2021 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Darina Šikrová, Vlad A. Cadar, Yavuz Ariyürek, Jeroen F. J. Laros, Judit Balog, Silvère M. van der Maarel
25citations -
Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells2024 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Qian Wang, Sabrina Capelletti, Jin Liu, Josephine M. Janssen, Manuel A.F.V. Gonçalves
24citations -
CRISPR/Cas9 Mutagenesis by Translocation of Cas9 Protein Into Plant Cells via the Agrobacterium Type IV Secretion System2020 Frontiers in Genome Editing article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Daan J. Schmitz, Zahir Ali, Chenglong Wang, Fatimah Aljedaani, Paul J. J. Hooykaas, Magdy M. Mahfouz, +1 more
23citations
Most active Aachen authors
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Marcel Tijsterman 7,224 citations overall17 papers
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Manuel A.F.V. Gonçalves 3,415 citations overall16 papers
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Robin van Schendel 2,163 citations overall15 papers
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Christine L. Mummery 40,132 citations overall9 papers
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Richard P. Davis 7,219 citations overall9 papers
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Niels Geijsen 6,718 citations overall9 papers
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Josephine M. Janssen 1,711 citations overall8 papers
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Susana M. Chuva de Sousa Lopes 18,829 citations overall7 papers
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Peng Shang 847 citations overall7 papers
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Albert Blanch-Asensio 140 citations overall7 papers
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Paul J. J. Hooykaas 20,347 citations overall6 papers
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Joost Schimmel 2,411 citations overall5 papers
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Sylvia de Pater 1,594 citations overall5 papers
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Qian Wang 867 citations overall5 papers
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Bastian Nießing 465 citations overall5 papers