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CRISPR and Genetic Engineering Sign in to save
Papers per year
Papers 122
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A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery2022 Journal of Cellular Biochemistry article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Amit Khurana, Nilofer Sayed, Vishakha Singh, Isha Khurana, Prince Allawadhi, Pushkar Singh Rawat, +4 more
22citations -
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells2022 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Francesca Tasca, Marcella Brescia, Qian Wang, Jin Liu, Josephine M. Janssen, Károly Szuhai, +1 more
21citations -
Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads2022 Stem Cell Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Albert Blanch-Asensio, Babet van der Vaart, Mariana Vinagre, Eline Groen, Christiaan H. Arendzen, Christian M.A.H. Freund, +3 more
20citations -
Gene targeting in polymerase theta‐deficient Arabidopsis thaliana2021 The Plant Journal article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Niels van Tol, Robin van Schendel, Alex Bos, Maartje van Kregten, Sylvia de Pater, Paul J. J. Hooykaas, +1 more
19citations -
Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants2023 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Qian Wang, Jin Liu, Josephine M. Janssen, Manuel A.F.V. Gonçalves
19citations -
Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs2024 Nature Biomedical Engineering article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Yufeng Li, Minkang Tan, Almira Akkari-Henić, L.S. Zhang, Maarten Kip, Jorian J. Sepers, +9 more
19citations -
CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Thomas Leisen, Fabian Bietz, Alex Wegner, Ulrich Schaffrath, David Scheuring, Felix Willmund, +3 more
18citations -
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations2024 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Ivan Kuzmin, Marilin Moor, Núria Muñoz-Subirana, +7 more
18citations -
Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs2024 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Zhen Li, Xiaoling Wang, Josephine M. Janssen, Jin Liu, Francesca Tasca, Rob C. Hoeben, +1 more
15citations -
CRISPR/Cas9 editing in conditionally immortalized HoxB8 cells for studying gene regulation in mouse dendritic cells2021 European Journal of Immunology article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Huaming Xu, Thomas A. Look, Sujeethkumar Prithiviraj, Daniel Lennartz, Manuel Delgado Cáceres, Katrin Götz, +5 more
13citations -
Analyzing the functional effects of DNA variants with gene editing2024 Cell Reports Methods article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 2 patents
Sarah Cooper, Sofia Obolenski, Andrew J. Waters, Andrew Roger Bassett, Matthew A. Coelho
13citations -
STRAIGHT-IN Dual: a platform for dual single-copy integrations of DNA payloads and gene circuits into human induced pluripotent stem cells2026 Nature Biomedical Engineering article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Albert Blanch-Asensio, Deon S. Ploessl, Nathan B. Wang, Christine L. Mummery, Kate E. Galloway, Richard P. Davis
13citations -
Targeted mutagenesis in Nicotiana tabacum ADF gene using shockwave‐mediated ribonucleoprotein delivery increases osmotic stress tolerance2021 Physiologia Plantarum article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Sruthy Maria Augustine, Anoop Vadakan Cherian, Kerstin Seiling, Nicole P. G. Raven, Ulrich Commandeur, Stefan Schillberg
12citations -
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Alessia Cavazza, Ayal Hendel, Rasmus Otkjær Bak, Paula Rı́o, Marc Güell, Duško Lainšček, +33 more
12citations -
Genetic dissection of mutagenic repair and T-DNA capture at CRISPR-induced DNA breaks in Arabidopsis thaliana2024 PNAS Nexus article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lycka Kamoen, Lejon E. M. Kralemann, Robin van Schendel, Niels van Tol, Paul J. J. Hooykaas, Sylvia de Pater, +1 more
12citations -
STRAIGHT-IN: a platform for rapidly generating panels of genetically modified human pluripotent stem cell lines2024 Nature Protocols article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering
Albert Blanch-Asensio, Catarina Grandela, Christine L. Mummery, Richard P. Davis
12citations -
Sensitive and reliable evaluation of single-cut sgRNAs to restore dystrophin by a GFP-reporter assay2020 PLoS ONE article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Pin Lyu, Kyung Whan Yoo, Manish Yadav, Anthony Atala, Annemieke M Aartsma-Rus, Maaike van Putten, +1 more
10citations
Most active Aachen authors
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Marcel Tijsterman 7,224 citations overall17 papers
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Manuel A.F.V. Gonçalves 3,415 citations overall16 papers
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Robin van Schendel 2,163 citations overall15 papers
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Christine L. Mummery 40,132 citations overall9 papers
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Richard P. Davis 7,219 citations overall9 papers
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Niels Geijsen 6,718 citations overall9 papers
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Josephine M. Janssen 1,711 citations overall8 papers
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Susana M. Chuva de Sousa Lopes 18,829 citations overall7 papers
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Peng Shang 847 citations overall7 papers
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Albert Blanch-Asensio 140 citations overall7 papers
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Paul J. J. Hooykaas 20,347 citations overall6 papers
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Joost Schimmel 2,411 citations overall5 papers
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Sylvia de Pater 1,594 citations overall5 papers
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Qian Wang 867 citations overall5 papers
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Bastian Nießing 465 citations overall5 papers