Aachen papers per year
Papers 37
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Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group2025 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Alessia Cavazza, Francisco Javier Molina-Estévez, Álvaro Plaza Reyes, Victor Ronco, Asma Naseem, Špela Malenšek, +30 more
67citations -
Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer2022 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Iolanda Scognamiglio, Lorenza Cocca, Ilaria Puoti, Francesco Ingenito, Cristina Quintavalle, Alessandra Affinito, +9 more
54citations -
C/D box snoRNA SNORD113-6 guides 2′-O-methylation and protects against site-specific fragmentation of tRNALeu(TAA) in vascular remodeling2022 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA modifications and cancer Open access
Eva van Ingen, Pleun A.M. Engbers, Tamar Woudenberg, M. Leontien van der Bent, Hailiang Mei, Johann Wojta, +2 more
47citations -
Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia2020 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA regulation and disease Open access
Reginald V.C.T. van der Kwast, Laura Parma, M. Leontien van der Bent, Eva van Ingen, Fabiana Baganha, Hendrika A. B. Peters, +6 more
44citations -
Antisense oligonucleotide therapy corrects splicing in the common Stargardt disease type 1-causing variant ABCA4 c.5461-10T>C2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Melita Kaltak, Davide Piccolo, Sang‐Eun Lee, Kalyan Dulla, Thomas Hoogenboezem, Wouter Beumer, +5 more
41citations -
Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis2021 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Eva van Ingen, Amanda C. Foks, Tamar Woudenberg, M. Leontien van der Bent, Alwin de Jong, Philipp J. Hohensinner, +4 more
37citations -
Systemic delivery of a DUX4-targeting antisense oligonucleotide to treat facioscapulohumeral muscular dystrophy2021 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access cited by 5 patents
Linde F. Bouwman, Bianca den Hamer, Anita van den Heuvel, Marnix Franken, Michaela Jackson, Chrissa A. Dwyer, +4 more
34citations -
Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy2021 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 2 patents
Darina Šikrová, Vlad A. Cadar, Yavuz Ariyürek, Jeroen F. J. Laros, Judit Balog, Silvère M. van der Maarel
23citations -
LINC00675 Suppresses Cell Proliferation and Migration via Downregulating the H3K4me2 Level at the SPRY4 Promoter in Gastric Cancer2020 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Yutian Pan, Yuan Fang, Mengyan Xie, Yu Liu, Tao Yu, Xi Wu, +3 more
21citations -
Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/neurodegenerative diseases2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA regulation and disease Open access
Korina Karagianni, Alessia Bibi, Alisia Madè, Shubhra Acharya, Mikko Parkkonen, Teodora Barbălată, +7 more
21citations -
Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration2022 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Hugo Fernandes, Alessandra Zonnari, Ricardo Cerqueira de Abreu, Sezin Aday, Marta Barão, Inês Albino, +13 more
21citations -
Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, +1 more
19citations -
Histone deacetylase inhibitors improve antisense-mediated exon-skipping efficacy in mdx mice2022 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Flavien Bizot, Remko Goossens, Thomas Tensorer, Luis Alberto Garcia, Annemieke M Aartsma-Rus, Pietro Spitali, +1 more
17citations -
Filamin A pre-mRNA editing modulates vascularization and tumor growth2022 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA regulation and disease Open access
Mamta K Jain, Greeshma Manjaly, Kathrin Maly, Margreet R. de Vries, Michael Peter Janisiw, Lisa König, +2 more
14citations -
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Alessia Cavazza, Ayal Hendel, Rasmus Otkjær Bak, Paula Rı́o, Marc Güell, Duško Lainšček, +33 more
12citations -
Tailored antisense oligonucleotides for ultrarare CNS diseases: An experience-based best practice framework for individual patient evaluation2025 Molecular Therapy — Nucleic Acids article Medicine Neurogenetic and Muscular Disorders Research Open access
Rebecca Schüle, Holm Graeßner, Annemieke M Aartsma-Rus, Willeke van Roon‐Mom, Matthis Synofzik
10citations -
High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Francesca Tasca, Marcella Brescia, Jin Liu, Josephine M. Janssen, Kamel Mamchaoui, Manuel A.F.V. Gonçalves
7citations -
CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer2024 Molecular Therapy — Nucleic Acids article Medicine CAR-T cell therapy research Open access cited by 3 patents
Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, +9 more
7citations -
Targeting long non-coding RNA MALAT1 preserves endothelial cell integrity and protects against kidney fibrosis2025 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Zhao Qiao, Loïs A.K. van der Pluijm, Morgane Gourvest, Atefeh Lafzi, Daniel Peled, Juliette A. de Klerk, +11 more
5citations
Most active Aachen authors
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Paul H.A. Quax 16,452 citations overall5 papers
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Anne Yaël Nossent 2,676 citations overall5 papers
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Annemieke M Aartsma-Rus 20,730 citations overall4 papers
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Manuel A.F.V. Gonçalves 3,415 citations overall4 papers
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Roel Bijkerk 2,034 citations overall4 papers
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M. Leontien van der Bent 565 citations overall4 papers
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Joris I. Rotmans 26,291 citations overall3 papers
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Anton Jan van Zonneveld 13,942 citations overall3 papers
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Margreet R. de Vries 6,156 citations overall3 papers
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Eva van Ingen 442 citations overall3 papers
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Tamar Woudenberg 228 citations overall3 papers
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Juliette A. de Klerk 119 citations overall3 papers
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Silvère M. van der Maarel 21,665 citations overall2 papers
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Hailiang Mei 10,927 citations overall2 papers
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Leen M. ‘t Hart 10,909 citations overall2 papers