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Virus-based gene therapy research Sign in to save
Papers per year
Papers 122
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Gene therapy: Comprehensive overview and therapeutic applications2022 Life Sciences article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research cited by 1 patent
Nilofer Sayed, Prince Allawadhi, Amit Khurana, Vishakha Singh, Umashanker Navik, Sravan Kumar Pasumarthi, +4 more
339citations -
Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays101citations
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Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment2020 Vaccine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 2 patents
Jerome H. H. V. Custers, Denny Kim, Maarten Leyssen, Marc Gurwith, Frank L. Tomaka, James S. Robertson, +10 more
84citations -
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 5 patents
Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Stefan Bernhard Thalhammer, David Manuel Mittas, Nina Karguth, Dina Yehia Otify, +15 more
83citations -
Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD462020 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Björn David Persson, Lijo John, Karim Rafie, Michael Strebl, Lars Frängsmyr, Mónika Z. Ballmann, +6 more
73citations -
Preconditioning of the tumor microenvironment with oncolytic reovirus converts CD3-bispecific antibody treatment into effective immunotherapy2020 Journal for ImmunoTherapy of Cancer article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Christianne Groeneveldt, Priscilla Kinderman, Diana J.M. van den Wollenberg, Ruben L van den Oever, Jim Middelburg, Dana A. M. Mustafa, +4 more
61citations -
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Josse A. Depla, Marina Sogorb-González, Lance Mulder, Vivi Majella Heine, Pavlina S. Konstantinova, Sander J. van Deventer, +4 more
53citations -
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper‐IgM syndrome2021 EMBO Molecular Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 7 patents
Valentina Vavassori, Elisabetta Mercuri, Genni Enza Marcovecchio, Maria Carmina Castiello, Giulia Schiroli, Luisa Albano, +17 more
53citations -
Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning2021 Molecular Therapy article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Adrian Schwarzer, Steven Roger Talbot, Anton Selich, Michael Alexander Morgan, Juliane Wilhelmine Schott, Oliver Dittrich‐Breiholz, +11 more
51citations -
Access to gene therapy for rare diseases when commercialization is not fit for purpose2023 Nature Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Thomas Andrew Fox, Juan Antonio Bueren, Fabio Candotti, Alain Fischer, Alessandro Aiuti, Arjan C. Lankester, +11 more
50citations -
Intrastriatal Administration of AAV5-miHTT in Non-Human Primates and Rats Is Well Tolerated and Results in miHTT Transgene Expression in Key Areas of Huntington Disease Pathology2021 Brain Sciences article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Elisabeth A. Spronck, Astrid Vallès, Margit H. Lampen, Paula S. Montenegro-Miranda, Sonay Keskin, Liesbeth Heijink, +5 more
48citations -
Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective2022 Journal of Molecular Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Julian Tristan Schwartze, Menzo J E Havenga, Wilfried A.M. Bakker, Angela C. Bradshaw, Stuart A. Nicklin
39citations -
Transduction patterns in the CNS following various routes of AAV-5-mediated gene delivery2020 Gene Therapy article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Kimberly L. Pietersz, Raygene Martier, M. S. Baatje, Jolanda M.P. Liefhebber, Cynthia C. Brouwers, Stephan M. Pouw, +7 more
37citations -
Biomarker screen for efficacy of oncolytic virotherapy in patient-derived pancreatic cancer cultures2024 EBioMedicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Theresa E. Schäfer, Lisanne I Knol, Ferdinand V. Haas, Anna Hartley, Sophie C S Pernickel, Attila Jády, +24 more
34citations
Most active Aachen authors
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Rob C. Hoeben 10,065 citations overall28 papers
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Vera Kemp 403 citations overall13 papers
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Frank J. T. Staal 18,191 citations overall12 papers
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Diana J.M. van den Wollenberg 1,706 citations overall12 papers
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Priscilla Kinderman 265 citations overall11 papers
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Thorbald van Hall 12,094 citations overall6 papers
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Gabri van der Pluijm 9,074 citations overall6 papers