Papers matching “competitive binding assay” 30
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High-throughput competitive binding assay for targeting RNA tertiary structures with small molecules: application to pseudoknots and G-quadruplexes2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Sophie E.L. Wintermans, Jana S Hoffmann, Victor van Kuijk, Yelda Durmus, Mariska D. Tacoma, Indy Broekhuizen, +6 more
1citations -
High-throughput competitive binding assay for targeting RNA with small molecules: discovery of new PreQ 1 riboswitch ligands2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology RNA and protein synthesis mechanisms Open access
Sophie E.L. Wintermans, Jana S Hoffmann, Mariska D. Tacoma, Indy Broekhuizen, Bjorn R. van Doodewaerd, Paul P. Geurink, +3 more
1citations -
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cannabis and Cannabinoid Research Open access
Leire Borrega Roman, Bradley L. Hoare, Miroslav Kosar, Roman C. Sarott, Kacper J. Patej, Jara Bouma, +15 more
0citations -
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues2020 The Journal of Immunology article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access cited by 1 patent
Paula Ruibal, Kees L. M. C. Franken, Krista E. van Meijgaarden, Joeri J. F. van Loon, Dirk van der Steen, Mirjam H.M. Heemskerk, +2 more
38citations -
Exploring the binding kinetics of intracellular allosteric antagonists for CC chemokine receptor 2 — a key to improve insurmountable antagonism2026 Biochemical Pharmacology article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Yao Yao, Lisa S. den Hollander, Bente T.M. Bleijs, Thomas Härtung, Uwe Grether, Natalia V. Ortiz Zacarı́as, +1 more
1citations -
Kinetic profiling of novel spirobenzo-oxazinepiperidinone derivatives as equilibrative nucleoside transporter 1 inhibitors2023 Purinergic Signalling article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling Open access
Anna Vlachodimou, Jara Bouma, Michel De Cleyn, Didier Berthelot, Stefan Pype, Jean-Paul Bosmans, +4 more
6citations -
Evaluating BindCraft for Generative Design of High-Affinity Peptides2025 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Mike Filius, Thanasis Patsos, Hugo Minnee, Jingming Liu, Monika T. Gnatzy, Ramon S. M. Rooth, +5 more
16citations -
Discovery of a novel chemotype targeting Mycobacterium tuberculosis cytochrome bd through rapid screening and structural elucidation2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tuberculosis Research and Epidemiology Open access
Tijn T. van der Velden, Asad Halimi, J.P.V. Pols, Wing-Sam Lam, Stephan M. Hacker, Lars J. C. Jeuken
0citations -
HpBoRB, a helminth-derived CCP domain protein which binds RELMβ2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Parasites and Host Interactions Open access
Vivien Shek, Abhishek Jamwal, Danielle J. Smyth, Tania G. Frangova, Alice R Savage, Gavin James Wright, +6 more
0citations -
Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays2024 ACS Chemical Neuroscience article Biochemistry, Genetics and Molecular Biology Amino Acid Enzymes and Metabolism Open access
Lieve van Veggel, Tamara A. M. Mocking, Hubert J. Sijben, Rongfang Liu, Marina Gorostiola González, Majlen A. Dilweg, +11 more
8citations -
LINC00675 Suppresses Cell Proliferation and Migration via Downregulating the H3K4me2 Level at the SPRY4 Promoter in Gastric Cancer2020 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Yutian Pan, Yuan Fang, Mengyan Xie, Yu Liu, Tao Yu, Xi Wu, +3 more
21citations -
Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Myasthenia Gravis and Thymoma Open access
Jamie L. Lim, Stine Marie Jensen, Jaap J. Plomp, Bernhardt Vankerckhoven, Christa Kneip, Rani Coppejans, +11 more
0citations -
Targeting the Kv11.1 (hERG) channel with allosteric modulators. Synthesis and biological evaluation of three novel series of LUF7346 derivatives2020 European Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Jacobus P. D. van Veldhoven, Giulia Campostrini, Constantijn J.E. van Gessel, Dorien Ward‐van Oostwaard, Rongfang Liu, Christine L. Mummery, +2 more
7citations -
The long non-coding RNA CRNDE promotes osteosarcoma proliferation and migration by sponging miR-136-5p/MRP9 axis2022 Annals of Translational Medicine article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Xiaomin Ding, Yawen Zhang, Jinrong Liang, Junyi Yin, Naveed Akbar, Verónica Miguel, +1 more
5citations -
A Comprehensive Guide for Assessing Covalent Inhibition in Enzymatic Assays Illustrated with Kinetic Simulations2022 Current Protocols article Biochemistry, Genetics and Molecular Biology Enzyme function and inhibition Open access
Elma Mons, Sander Roet, Robbert Q. Kim, Monique P. C. Mulder
109citations -
Identification of acetylshikonin as a novel tubulin polymerization inhibitor with antitumor activity in human hepatocellular carcinoma cells2023 Journal of Gastrointestinal Oncology article Biochemistry, Genetics and Molecular Biology Microtubule and mitosis dynamics Open access
Yongchuan Li, Junqiu Zhou, Kun Xu, Yanqing Pang, Ralf Weiskirchen, Matthias Ocker, +1 more
2citations -
Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD462020 Proceedings of the National Academy of Sciences article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Björn David Persson, Lijo John, Karim Rafie, Michael Strebl, Lars Frängsmyr, Mónika Z. Ballmann, +6 more
73citations