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Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Molecular characterization of Cdh12-SCON conditional knockout mice reveals unexpected splicing changes2026 Transgenic Research article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Mayke A C Ten Hoor, Margot M. L. Linssen, Conny M. Brouwers, Jill W. C. Claassens, Jaap Mulder, Peter Hohenstein
0citations -
High sorbic acid resistance of Penicillium roqueforti is mediated by the SORBUS gene cluster2022 PLoS Genetics article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Maarten Punt, Sjoerd J. Seekles, Jisca L. van Dam, Connor de Adelhart Toorop, Raithel R. Martina, Jos A. M. P. Houbraken, +3 more
15citations -
SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection2022 Experimental & Molecular Medicine article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Szu-Hsien Sam Wu, Heetak Lee, Réka Szép-Bakonyi, Gabriele Colozza, Ayse Boese, Krista R. Gert, +10 more
8citations -
Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer2025 Scientific Reports article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access
Mirvat Surakhy, David Barnes, Emma J. Carter, Jennifer Hughes, Claudia Bühnemann, Sabina Sanegre, +4 more
2citations -
PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting2021 Angiogenesis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Paola Perrotta, Margreet R. de Vries, Bart Peeters, Pieter‐Jan Guns, Guido R.Y. De Meyer, Paul H.A. Quax, +1 more
30citations -
PRMT4 inhibitor TP-064 impacts both inflammatory and metabolic processes without changing the susceptibility for early atherosclerotic lesions in male apolipoprotein E knockout mice2021 Atherosclerosis article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yiheng Zhang, Robin A.F. Verwilligen, Timothy J. P. Sijsenaar, Miranda Van Eck, Menno Hoekstra
14citations -
GRHL2-controlled gene expression networks in luminal breast cancer2023 Cell Communication and Signaling article Biochemistry, Genetics and Molecular Biology Estrogen and related hormone effects Open access
Zi Wang, Bircan Coban, Haoyu Wu, Jihed Chouaref, Lucia Daxinger, Michelle T. Paulsen, +4 more
32citations -
A seven-membered cell wall related transglycosylase gene family in Aspergillus niger is relevant for cell wall integrity in cell wall mutants with reduced α-glucan or galactomannan2020 The Cell Surface article Biochemistry, Genetics and Molecular Biology Fungal and yeast genetics research Open access
Tim M. van Leeuwe, Jasper Wattjes, Anna Niehues, Gabriel Forn‐Cuní, Nicholas Geoffrion, Hugo Mélida, +7 more
23citations -
Preclinical efficacy and safety of adeno-associated virus 5 alpha-galactosidase: A gene therapy for Fabry disease2024 Molecular Therapy — Methods & Clinical Development article Medicine Lysosomal Storage Disorders Research Open access
Jolanda M.P. Liefhebber, Giso Brasser, Elisabeth A. Spronck, Roelof Ottenhoff, Lieke Paerels, Maria J. Ferraz, +6 more
9citations -
Sequential deregulation of histone marks, chromatin accessibility and gene expression in response to PROTAC-induced degradation of ASH2L2023 Scientific Reports article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Mirna Barsoum, Roksaneh Sayadi-Boroujeni, Alexander T. Stenzel, Philip Bussmann, Juliane Lüscher‐Firzlaff, Bernhard Lüscher
5citations -
Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low‐density lipoprotein receptor knockout mice2024 The Journal of Physiology article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Menno Hoekstra, Olga S.C. Snip, Philip Janusz, Mireia N. A. Bernabé Kleijn, Edward R. Truitt, Benjamin David Sullivan, +3 more
3citations -
CRISPR-Cas knockout of miR21 reduces glioma growth2022 Molecular Therapy — Oncolytics article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Lisa Nieland, Thomas S. van Solinge, Pike-See Cheah, Liza M. Morsett, Joseph B. El Khoury, Joseph I. Rissman, +4 more
42citations -
CRISPR/Cas9 mediated CXCL4 knockout in human iPS cells of polycythemia vera patient with JAK2 V617F mutation2021 Stem Cell Research article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access
Janik Boehnke, Salim Atakhanov, Marcelo A. S. Toledo, Herdit M. Schüler, Stephanie Sontag, Nicolas Chatain, +4 more
2citations -
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma2021 npj Systems Biology and Applications article Chemistry Advanced Proteomics Techniques and Applications Open access
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David J. Schibli, +6 more
7citations -
Myofiber-specific knockout of TGF-β type I receptors in mice concurrently drives muscle hypertrophy, oxidative metabolism, and absolute force2026 Communications Biology article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Andi Shi, Michèle MG Hillege, Wendy Noort, Carla Offringa, Gang Wu, Tim Forouzanfar, +3 more
0citations -
Inhibition of pannexin‐1 does not restore electrolyte balance in precystic Pkd1 knockout mice2024 Physiological Reports article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Wouter H. van Megen, Teun J. van Houtert, Caro Bos, Dorien J.M. Peters, Jeroen H. F. de Baaij, Joost G.J. Hoenderop
4citations