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Cancer-related gene regulation Sign in to save
Papers per year
Papers 12
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Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Roko Žaja, Gülcan Aydın, Barbara E. Lippok, Regina Feederle, Bernhard Lüscher, Karla L. H. Feijs
43citations -
Identification of PRMT5 as a therapeutic target in cholangiocarcinoma2024 Gut article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Jasmin Elurbide, Leticia Colyn, Maria Ujue Latasa, Iker Uriarte, Amaya López-Pascual, Emiliana Valbuena, +24 more
30citations -
Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers2025 Annals of Oncology article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
M.M. Gounder, Patricia Martín-Romano, Antoîne Italiano, L. L. Siu, Philippe Alexandre Cassier, Gerald Steven Falchook, +15 more
17citations -
PRMT5 inhibition induces pro‐inflammatory macrophage polarization and increased hepatic triglyceride levels without affecting atherosclerosis in mice2023 Journal of Cellular and Molecular Medicine article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yiheng Zhang, Robin A.F. Verwilligen, Miranda Van Eck, Menno Hoekstra
15citations -
456MO METEOR-1: A phase I study of the safety and efficacy of the protein arginine methyltransferase 5 (PRMT5) inhibitor GSK3326595 in advanced solid tumors2022 Annals of Oncology article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
S. Postel-Vinay, Antoîne Italiano, Philippe Alexandre Cassier, L.L. Siu, I. S. Lossos, J.F. Hilton, +13 more
15citations -
PRMT4 inhibitor TP-064 impacts both inflammatory and metabolic processes without changing the susceptibility for early atherosclerotic lesions in male apolipoprotein E knockout mice2021 Atherosclerosis article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yiheng Zhang, Robin A.F. Verwilligen, Timothy J. P. Sijsenaar, Miranda Van Eck, Menno Hoekstra
14citations -
PRMT4 inhibitor TP-064 inhibits the pro-inflammatory macrophage lipopolysaccharide response in vitro and ex vivo and induces peritonitis-associated neutrophilia in vivo2021 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yiheng Zhang, Ezra J. van der Wel, Miranda Van Eck, Menno Hoekstra
11citations -
Structural Studies Provide New Insights into the Role of Lysine Acetylation on Substrate Recognition by CARM1 and Inform the Design of Potent Peptidomimetic Inhibitors2021 ChemBioChem article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yurui Zhang, N. Marechal, Matthijs J. van Haren, N. Troffer-Charlier, Vincent Cura, J. Cavarelli, +1 more
6citations -
A Direct Assay for Measuring the Activity and Inhibition of Coactivator-Associated Arginine Methyltransferase 12022 Biochemistry article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yurui Zhang, Matthijs J. van Haren, N. Marechal, N. Troffer-Charlier, Vincent Cura, J. Cavarelli, +1 more
3citations -
A suite of macrocyclic peptide inhibitors and substrate probes for arginine methyltransferases2026 Chemical Science article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Ryoji Yoshisada, Yurui Zhang, Elwin Janssen, Caroline Bouchard, David Alonzo Poole III, Tianzheng Wan, +13 more
0citations
12 results
Most active Aachen authors
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Menno Hoekstra 6,099 citations overall4 papers
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Miranda Van Eck 10,762 citations overall3 papers
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Nathaniel I. Martin 5,461 citations overall3 papers
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Yurui Zhang 1,262 citations overall3 papers
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Matthijs J. van Haren 1,050 citations overall3 papers
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Robin A.F. Verwilligen 331 citations overall2 papers
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Yiheng Zhang 38 citations overall2 papers
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Bernhard Lüscher 21,345 citations overall1 paper
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Elmar G. Weinhold 6,262 citations overall1 paper
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Kai Markus Schneider 4,060 citations overall1 paper
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Roko Žaja 3,657 citations overall1 paper
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Joost S.P. Vermaat 3,482 citations overall1 paper
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Yiheng Zhang 2,145 citations overall1 paper
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Karla L. H. Feijs 2,015 citations overall1 paper
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Barbara E. Lippok 687 citations overall1 paper