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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease2021 Scientific Reports article Computer Science Computational Drug Discovery Methods Open access cited by 1 patent
Michael G. Sugiyama, Haotian Cui, Dar’ya S. Redka, Mehran Karimzadeh, Edurne Rujas, Hassaan Maan, +16 more
23citations -
Targeting chitinase-3-like protein-1 in pancolitis by a drug-repurposing approach2026 Biochemical Pharmacology article Biochemistry, Genetics and Molecular Biology Studies on Chitinases and Chitosanases Open access
Faranak Bahramimehr, Stefanie Kurz, Axel Guthart, Susanne M. Krug, Anja Fromm, Damian Tarasek, +11 more
0citations -
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing Screen2021 ACS Pharmacology & Translational Science article Computer Science Computational Drug Discovery Methods Open access cited by 8 patents
Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Bernhard Ellinger, +26 more
160citations -
Pandemic Drugs at Pandemic Speed: Infrastructure for Accelerating COVID-19 Drug Discovery with Hybrid Machine Learning- and Physics-based Simulations on High Performance Computers2021 arXiv (Cornell University) preprint Computer Science Computational Drug Discovery Methods Open access
Agastya P. Bhati, Shunzhou Wan, Austin Clyde, Mathis Bode, Mikhail Titov, André Merzky, +20 more
42citations -
High-throughput profiling of drug interactions in Gram-positive bacteria2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
Elisabetta Cacace, Vladislav Kim, Michael R. Knopp, Manuela Tietgen, Amber Brauer-Nikonow, Kemal İnecik, +13 more
2citations -
Omics-Mediated Treatment for Advanced Prostate Cancer: Moving Towards Precision Oncology2025 International Journal of Molecular Sciences article Medicine Prostate Cancer Treatment and Research Open access
Yasra Fatima, Kirubel Nigusu Jobre, Enrique Gómez‐Gómez, Bartosz Małkiewicz, Antonia Vlahou, Marika Mokou, +3 more
10citations -
Identification of a PRDM1-regulated T cell network to regulate atherosclerotic plaque inflammation2025 Genome Medicine article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Han Young Jin, Sanne Lidewij Maas, Yuchi Zou, Chang Wei Lu, Baixue Yu, Rosanna Huchzermeier, +12 more
5citations -
Tiprelestat for treatment of hospitalized COVID-19: results of the double-blind randomized placebo-controlled COMCOVID trial2025 Advances in Therapy article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Ingmar Bergs, Stephan Budweiser, Hans‐Heinrich Henneicke‐von Zepelin, Hagen Kelm, Tom Bollmann, Johannes-Josef Tebbe, +6 more
0citations -
Identification of a gene network driving the attenuated response to lipopolysaccharide of monocytes from hypertensive coronary artery disease patients2024 Frontiers in Immunology article Medicine Adipokines, Inflammation, and Metabolic Diseases Open access
Chang Wei Lu, Marjo M. P. C. Donners, Julius B. J. de Baaij, Han Young Jin, Jeroen J. T. Otten, Marco Manca, +11 more
2citations -
Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro2022 Frontiers in Cardiovascular Medicine article Medicine Parathyroid Disorders and Treatments Open access
Marina Augusto Heuschkel, Anne Babler, Jonas Heyn, Emiel P. C. van der Vorst, Marja Steenman, Maren Gesper, +8 more
20citations -
Preclinical validation of PKC412 as a therapy candidate for epidermolysis bullosa simplex across multiple keratin pathogenic variants2025 British Journal of Dermatology article Biochemistry, Genetics and Molecular Biology Skin and Cellular Biology Research Open access
Henriette Jopp, A Kraft, Bernd Hoffmann, Rudolf Merkel, M. Bishr Omary, Cristina Has, +2 more
3citations -
A muscle growth-promoting treatment based on the attenuation of activin/myostatin signalling results in long-term testicular abnormalities2021 Disease Models & Mechanisms article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Danielle Vaughan, Robert D. Mitchell, Oliver Kretz, David J. Chambers, Maciej M. Lalowski, Helge Amthor, +9 more
1citations -
Abstract P156: Intimal And Medial Calcification Underlie Differential Molecular Mechanisms2021 Arteriosclerosis Thrombosis and Vascular Biology conference-abstract Medicine Parathyroid Disorders and Treatments
Marina Augusto Heuschkel, Jonas Heyn, Emiel P. C. van der Vorst, Nikolaus Marx, Claudia Goettsch
0citations -
PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Phosphodiesterase function and regulation Open access
Xuhuang Fu, Anne Kaiser, Payal Chawla, Axel Choidas, Peter Habenberger, Tiago Maié, +17 more
0citations