Papers matching “drug combination screening” 99
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Combination Of Computational Methods With A Drug Repurposing Strategy Identifies A Compound Targeting Chondrocyte Hypertrophy2023 Osteoarthritis and Cartilage article Medicine Osteoarthritis Treatment and Mechanisms Open access
J. Veldman, M.N. Ferrao Blanco, N. Kops, K. Sivasubramaniyan, Jeroen van Rooij, E. Farrell, +1 more
1citations -
Biochemical reaction network topology defines dose-dependent Drug–Drug interactions2023 Computers in Biology and Medicine article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Mehrad Babaei, Tom M. J. Evers, Fereshteh Shokri, Lucia Altucci, Elizabeth C. M. de Lange, Alireza Mashaghi
12citations -
Interstitial Lung Disease in Patients With Systemic Sclerosis: Toward Personalized-Medicine-Based Prediction and Drug Screening Models of Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD)
Padmini P. S. J. Khedoe, Emiel R. Marges, Pieter Sicco Hiemstra, Maarten K. Ninaber, Miranda Geelhoed
24citations -
Robust and Scalable Angiogenesis Assay of Perfused 3D Human iPSC-Derived Endothelium for Anti-Angiogenic Drug Screening2020 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access
Vincent van Duinen, Wendy Stam, Farbod Famili, Arie Reijerkerk, Paul Vulto, Thomas Hankemeier, +1 more
40citations -
A drug-repurposing screen of FDA- and EMA-approved drugs identifies two NF-κB inhibitors active against eumycetoma2025 Journal of Antimicrobial Chemotherapy article Medicine Actinomycetales infections and treatment Open access
Jingyi Ma, Bjorn R. van Doodewaerd, Bernhard Biersack, Annelies Verbon, Paul P. Geurink, Wendy W. J. van de Sande
2citations -
Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 4 patents
Lukas Mathur, Bence Szalai, N. H. Du, Ramesh Utharala, Martine Ballinger, Jonathan J. M. Landry, +4 more
27citations -
Experimental mouse model of hepatocellular carcinoma with and without parenchymal liver damage for rapid screening of antitumor drugs2023 Zeitschrift für Gastroenterologie article Medicine Hepatocellular Carcinoma Treatment and Prognosis
Paul M. Schneider, Karina Benderski, Alexandros Marios Sofias, Twan Lammers, Barbara Schrörs, Mustafa Diken, +2 more
0citations -
Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma2022 Investigative Ophthalmology & Visual Science article Medicine Ocular Oncology and Treatments Open access
Kseniya Glinkina, Fariba Némati, Amina F.A.S. Teunisse, Maria Chiara Gelmi, Muriel J. Kuipers, Samar Alsafadi, +3 more
6citations -
Stratification and prediction of drug synergy based on target functional similarity2020 npj Systems Biology and Applications article Computer Science Computational Drug Discovery Methods Open access
Mi Yang, Patricia Jaaks, Jonathan R. Dry, Mathew J. Garnett, Michael P. Menden, Julio Sáez-Rodríguez
60citations -
Patient‐specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies2020 Molecular Systems Biology article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A. Merten, Mathew J. Garnett, +1 more
79citations -
Molecular Genetic Screening in Patients With ACE Inhibitor/Angiotensin Receptor Blocker-Induced Angioedema to Explore the Role of Hereditary Angioedema Genes2022 Frontiers in Genetics article Medicine Coagulation, Bradykinin, Polyphosphates, and Angioedema Open access
Carina M. Mathey, Carlo Maj, Annika B. Scheer, Julia Fazaal, Bettina Wedi, Dorothea Wieczorek, +25 more
13citations -
In Silico and Experimental ADAM17 Kinetic Modeling as Basis for Future Screening System for Modulators2022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access cited by 1 patent
Marian Bienstein, Dmitriy Minond, Ulrich Schwaneberg, Mehdi D. Davari, Daniela Yildiz
13citations -
Mechanism-based drug safety testing using innovative in vitro liver models: from DILI prediction to idiosyncratic DILI liability assessment2025 Expert Opinion on Drug Metabolism & Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Sibel Bahtiri, Tessa M. S. Hagens, Bob van de Water, Marije Niemeijer
3citations -
Integration of in vitro and in silico approaches enables prediction of drug-induced liver injury2026 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
René Geci, Ahenk Zeynep Sayin, Stephan Schaller, Lars Kuepfer
5citations -
The Development of Practice Recommendations for Drug-Disease Interactions by Literature Review and Expert Opinion2020 Frontiers in Pharmacology article Medicine Pharmaceutical Practices and Patient Outcomes Open access
Justine M. Z. van Tongeren, S. Froukje Harkes‐Idzinga, Heleen van der Sijs, Roya Atiqi, Bart J. F. van den Bemt, L.W. Draijer, +10 more
36citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 Journal of Biomolecular Structure and Dynamics article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
3citations -
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis2020 Respiratory Research article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access cited by 1 patent
Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki Barrett, Robert B. Good, +7 more
48citations