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Protease and Inhibitor Mechanisms Sign in to save
Papers per year
Papers 72
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Fazirsiran for Liver Disease Associated with Alpha 1 -Antitrypsin Deficiency2022 New England Journal of Medicine article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access cited by 3 patents
Pavel Strnad, Mattias Mandorfer, Gourab Choudhury, William J. Griffiths, Christian Trautwein, Rohit Seth Loomba, +7 more
120citations -
Liver Phenotypes of European Adults Heterozygous or Homozygous for Pi∗Z Variant of AAT (Pi∗MZ vs Pi∗ZZ genotype) and Noncarriers2020 Gastroenterology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Carolin Victoria Schneider, Karim Hamesch, Annika Groß, Mattias Mandorfer, Linda S. Moeller, Vítor Magno Pereira, +46 more
102citations -
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency2021 Gut article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Malin Fromme, Carolin Victoria Schneider, Vítor Magno Pereira, Karim Hamesch, Mònica Pons, Matthias Reichert, +38 more
80citations -
The metalloproteinase ADAM10 requires its activity to sustain surface expression2020 Cellular and Molecular Life Sciences article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Anke Seifert, Stefan Düsterhöft, Justyna Wozniak, Chek Ziu Koo, Michael G. Tomlinson, Elisa Nuti, +4 more
53citations -
Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA)2024 Gastroenterology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Virginia Clark, Charlie Strange, Pavel Strnad, Antonio J. Sanchez, Paul Yien Kwo, Vítor Magno Pereira, +18 more
31citations -
Proteolysis of the pericellular matrix: Pinpointing the role and involvement of matrix metalloproteinases in early osteoarthritic remodeling2024 Acta Biomaterialia article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Marina Danalache, Felix Umrath, Rosa Riester, Maik Schwitalle, Farshid Guilak, Ulf Krister Hofmann
29citations -
Circulating levels of soluble urokinase plasminogen activator receptor predict outcome after resection of biliary tract cancer2020 JHEP Reports article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Sven Heiko Loosen, Annemarie Breuer, Frank Tacke, Jakob Nikolas Kather, Joao Gorgulho, Patrick H. Alizai, +15 more
25citations -
The Relationship between Plasma Alpha-1-Antitrypsin Polymers and Lung or Liver Function in ZZ Alpha-1-Antitrypsin-Deficient Patients2022 Biomolecules article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Annelot D. Sark, Malin Fromme, Beata T. Olejnicka, Tobias Welte, Pavel Strnad, Sabina M Janciauskiene, +1 more
18citations -
Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Predict Tumor Response and Outcome to Immune Checkpoint Inhibitor Therapy2021 Frontiers in Oncology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access cited by 1 patent
Sven Heiko Loosen, Joao Gorgulho, Markus Sebastian Jördens, Maximilian Franz Schulze-Hagen, Fabian Beier, Mihael Vucur, +9 more
16citations -
Highly Selective Sub-Nanomolar Cathepsin S Inhibitors by Merging Fragment Binders with Nitrile Inhibitors2020 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms cited by 10 patents
Markus Schade, Beatrix Merla, Bernhard Lesch, Markus Wagener, Simone Timmermanns, Katrien Pletinckx, +1 more
15citations -
Alpha-1 Antitrypsin Augmentation and the Liver Phenotype of Adults With Alpha-1 Antitrypsin Deficiency (Genotype Pi∗ZZ)2023 Clinical Gastroenterology and Hepatology article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Malin Fromme, Karim Hamesch, Carolin Victoria Schneider, Mattias Mandorfer, Mònica Pons, Katrine Holtz Thorhauge, +36 more
12citations -
Review article: New developments in biomarkers and clinical drug development in alpha‐1 antitrypsin deficiency‐related liver disease2024 Alimentary Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Rohit Seth Loomba, Ginger Clark, Jeffrey H. Teckman, Veeral H. Ajmera, Cynthia A. Behling, Mark Brantly, +12 more
11citations
Most active Aachen authors
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Pavel Strnad 10,595 citations overall44 papers
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Malin Fromme 765 citations overall36 papers
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Christian Trautwein 60,353 citations overall21 papers
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Carolin Victoria Schneider 3,130 citations overall13 papers
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Karim Hamesch 1,577 citations overall11 papers
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Nurdan Güldiken 990 citations overall8 papers
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V Woditsch 480 citations overall8 papers
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C Schneider 2,457 citations overall7 papers
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Barbara Burbaum 213 citations overall7 papers
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Katharina Remih 158 citations overall6 papers
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Samira Amzou 79 citations overall6 papers
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Kai Markus Schneider 4,060 citations overall5 papers
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Nadine Therese Gaisa 3,965 citations overall5 papers
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Lisa Bewersdorf 172 citations overall5 papers
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Pavel Strnad 7,245 citations overall4 papers