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Drug-Induced Hepatotoxicity and Protection Sign in to save
Papers per year
Papers 76
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Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury2020 Cellular and Molecular Gastroenterology and Hepatology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Kai Markus Schneider, Carsten Elfers, Ahmed Ghallab, Carolin Victoria Schneider, Eric J. C. Gálvez, Antje Mohs, +18 more
108citations -
Comparing in vitro human liver models to in vivo human liver using RNA-Seq2020 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access cited by 1 patent
Yannick Schrooders, Duncan A. Hauser, Marcel van Herwijnen, Wiebke Albrecht, Bas ter Braak, Tim Brecklinghaus, +17 more
100citations -
Alpha-1 antitrypsin deficiency: A re-surfacing adult liver disorder2021 Journal of Hepatology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection
Malin Fromme, Carolin Victoria Schneider, Christian Trautwein, Nicola Brunetti‐Pierri, Pavel Strnad
89citations -
Histological and serological features of acute liver injury after SARS-CoV-2 vaccination2022 JHEP Reports article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Greta Codoni, Theresa Kirchner, Bastian Engel, Alejandra Villamil, Cumali Efe, Albert Friedrich Stättermayer, +33 more
52citations -
Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy2022 Cell Death and Disease article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access cited by 1 patent
Hui Ye, Chaobo Chen, Hanghang Wu, Kang Zheng, Beatriz Martín-Adrados, Esther Caparrós, +17 more
43citations -
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment2021 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulia Callegaro, Steven J. Kunnen, Panuwat Trairatphisan, Solène Grosdidier, Marije Niemeijer, Wouter den Hollander, +9 more
43citations -
Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury2021 Biochemical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Lukas S. Wijaya, Panuwat Trairatphisan, Attila Gábor, Marije Niemeijer, Jason Keet, Ariadna Alcalà Morera, +13 more
27citations -
Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds2022 Scientific Data data-paper Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marcha C. T. Verheijen, Uğis Sarkans, Witold Wolski, Danyel G. J. Jennen, Florian Caiment, Jos C. S. Kleinjans, +49 more
16citations -
A systems approach reveals species differences in hepatic stress response capacity2023 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giusy Russomanno, Rowena L. C. Sison-Young, Lucia A Livoti, Hannah Coghlan, Rosalind E. Jenkins, Steven J. Kunnen, +14 more
16citations -
Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors2024 Environmental Health Perspectives article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marije Niemeijer, Witold Więcek, Shuai Fu, Suzanna Huppelschoten, Peter Bouwman, Audrey Baze, +5 more
16citations -
The hepatotoxic fluoroquinolone trovafloxacin disturbs TNF- and LPS-induced p65 nuclear translocation in vivo and in vitro2020 Toxicology and Applied Pharmacology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulio Giustarini, Suzanna Huppelschoten, Angela Oppelt, Laura Wagenaar, Richard John Weaver, Marianne Bol‐Schoenmakers, +4 more
14citations -
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes2021 Toxicology in Vitro article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Bas ter Braak, Marije Niemeijer, Ruben Boon, Celine Parmentier, Audrey Baze, Lysiane Richert, +4 more
14citations -
Identifying multiscale translational safety biomarkers using a network-based systems approach2023 iScience article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulia Callegaro, Johannes P. Schimming, Janet Piñero, Steven J. Kunnen, Lukas S. Wijaya, Panuwat Trairatphisan, +7 more
14citations -
A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury2023 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Lukas S. Wijaya, Attila Gábor, Iris Pot, Luca van de Have, Julio Sáez-Rodríguez, James L. Stevens, +3 more
13citations -
C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8+ T cell homeostasis and response to acute liver injury2024 Hepatology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection
Patricia Maria Niemietz, Moritz Peiseler, Marlene Sophia Kohlhepp, Paul M. Horn, Kylie P. Matchett, Yuting Wang, +13 more
12citations -
Identification of proteome markers for drug-induced liver injury in zebrafish embryos2022 Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Marja Driessen, Suzanne J. van der Plas-Duivesteijn, Anne S. Kienhuis, Evert‐Jan van den Brandhof, Marianne Roodbergen, Bob van de Water, +4 more
10citations -
Genome‐wide Association Study of Methotrexate‐Induced Liver Injury in Rheumatoid Arthritis Patients2023 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Frank Eektimmerman, Jesse Joachim Swen, Alfons A den Broeder, Johanna M W Hazes, Fina Kurreeman, Suzanne M. M. Verstappen, +6 more
9citations
Most active Aachen authors
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Bob van de Water 13,491 citations overall34 papers
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Steven J. Kunnen 617 citations overall16 papers
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Giulia Callegaro 349 citations overall11 papers
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James L. Stevens 20,965 citations overall9 papers
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Joost B. Beltman 4,098 citations overall9 papers
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Marije Niemeijer 612 citations overall9 papers
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Lukas S. Wijaya 305 citations overall9 papers
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Pavel Strnad 10,595 citations overall7 papers
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Peter Bouwman 7,097 citations overall6 papers
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Steven Wink 881 citations overall6 papers
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Christian Trautwein 60,353 citations overall5 papers
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Katharina Remih 158 citations overall5 papers
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Lars Kuepfer 4,363 citations overall4 papers
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Wouter den Hollander 3,195 citations overall4 papers
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Sylvia E. Le Dévédec 3,049 citations overall4 papers