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Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease2020 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 2 patents
Marius Maximilian Woitok, Miguel Eugenio Zoubek, Dennis Doleschel, Matthias Bartneck, Mohamed Ramadan Mohamed, Fabian M. Kiessling, +3 more
53citations -
The application of M12L24 nanocages as cell-specific siRNA delivery agents in vitro2023 Chem article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Eduard O. Bobylev, Ye Zeng, Kevin Weijgertse, Emma Koelman, Bas de Bruin, Alexander Kros, +1 more
16citations -
Local release of siRNA using polyplex-loaded thermosensitive hydrogels2020 Nanoscale article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Lies A. L. Fliervoet, Heyang Zhang, Emma van Groesen, Kyra Fortuin, Naut J. C. B. Duin, Katrien Remaut, +3 more
43citations -
siRNA-based identification of IBD-related targets in human monocyte-derived dendritic cells2021 Journal of Immunological Methods article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Diane Bosman-Schluep, Remko de Pril, Banu Verbaken, Anaïs Legent, Jan Stallen, Esther C. de Jong, +1 more
1citations -
Development of a Combined Lipid-Based Nanoparticle Formulation for Enhanced siRNA Delivery to Vascular Endothelial Cells2022 Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 3 patents
Yutong He, Dongdong Bi, Josée A. Plantinga, Grietje Molema, Jeroen Bussmann, Jan A. A. M. Kamps
23citations -
Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery2022 Macromolecular Rapid Communications article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Leon Capelôa, Mina Yazdi, Heyang Zhang, Xiaobing Chen, Ernst Wagner, Ulrich Lächelt, +1 more
5citations -
Targeting liver angiotensinogen with siRNA enhances podocyte regeneration through renin lineage cells in experimental kidney disease2026 Molecular Therapy — Nucleic Acids article Medicine Renin-Angiotensin System Studies Open access
Loïs A.K. van der Pluijm, Angela Koudijs, A.H. Jan Danser, Joris I. Rotmans, Roel Bijkerk
0citations -
Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery2021 Macromolecular Rapid Communications article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Leon Capelôa, Mina Yazdi, Heyang Zhang, Xiaobing Chen, Yu Nie, Ernst Wagner, +2 more
12citations -
Culture medium used during small interfering RNA (siRNA) transfection determines the maturation status of dendritic cells2020 Journal of Immunological Methods article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Mieke F. van Essen, Nicole Schlagwein, Daniëlle J. van Gijlswijk‐Janssen, Jacqueline D.H. Anholts, Michael Eikmans, Jurjen M. Ruben, +1 more
11citations -
Multicompartment Polyion Complex Micelles Based on Triblock Polypept(o)ides Mediate Efficient siRNA Delivery to Cancer‐Associated Fibroblasts for Antistromal Therapy of Hepatocellular Carcinoma (Adv. Mater. 41/2024)2024 Advanced Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Paul M. Schneider, Heyang Zhang, Leon Simić, Barbara Schrörs, Özlem Akilli‐Öztürk, Lin Jian, +14 more
0citations -
Targeting Activated Hepatic Stellate Cells Using Collagen-Binding Chitosan Nanoparticles for siRNA Delivery to Fibrotic Livers2020 Pharmaceutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Menna Azzam, Sara Elsafy, Sarah A. Abdelgelil, Ralf Weiskirchen, Anastasia Asimakopoulou, Federica De Lorenzi, +3 more
40citations -
Multicompartment Polyion Complex Micelles Based on Triblock Polypept(o)ides Mediate Efficient siRNA Delivery to Cancer‐Associated Fibroblasts for Antistromal Therapy of Hepatocellular Carcinoma2024 Advanced Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Paul M. Schneider, Heyang Zhang, Leon Simić, Barbara Schrörs, Özlem Akilli‐Öztürk, Lin Jian, +14 more
33citations -
Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection2024 Nature Communications article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Roy Pattipeiluhu, Ye Zeng, Marco M. R. M. Hendrix, Ilja Karina Voets, Alexander Kros, Thomas Harry Sharp
120citations -
Targeting Ligand Independent Tropism of siRNA‐LNP by Small Molecules for Directed Therapy of Liver or Myeloid Immune Cells2023 Advanced Healthcare Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 1 patent
Cheng Lin, Alexander Jans, Justina Clarinda Wolters, Mohamed Ramadan Mohamed, Emiel P. C. van der Vorst, Christian Trautwein, +1 more
24citations -
Immunotherapeutic hydrogel for co-delivery of STAT3 siRNA liposomes and lidocaine hydrochloride for postoperative comprehensive management of NSCLC in a single application2024 Asian Journal of Pharmaceutical Sciences article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Xianglei Fu, Yanbin Shi, Zili Gu, Hengchang Zang, Lian Li, Qingjie Wang, +9 more
8citations -
Efficient Downregulation of Alk4 in Skeletal Muscle After Systemic Treatment with Conjugated siRNAs in a Mouse Model for Duchenne Muscular Dystrophy2022 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Sarah Engelbeen, Svetlana Pasteuning-Vuhman, Rubina Giare Parmar, Klaus Charissé, Laura Sepp‐Lorenzino, Muthiah A. Manoharan, +2 more
14citations -
Small interfering RNA–mediated allele-selective silencing of von Willebrand factor in vitro and in vivo2023 Blood Advances article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Yvonne K. Jongejan, Elisa Schrader Echeverri, Richard J. Dirven, Kalina Paunovska, Noa A. Linthorst, Annika de Jong, +5 more
20citations -
Targeting transthyretin ‐ Mechanism‐based treatment approaches and future perspectives in hereditary amyloidosis2020 Journal of Neurochemistry article Biochemistry, Genetics and Molecular Biology Amyloidosis: Diagnosis, Treatment, Outcomes Open access cited by 1 patent
Maike Franziska Dohrn, Sandra Michaela Ihne-Schubert, Ute Hegenbart, Jessica Medina, Stephan L. Zuchner, Teresa Coelho, +1 more
39citations