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Complement system in diseases Sign in to save
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Papers 197
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Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria2021 New England Journal of Medicine article Immunology and Microbiology Complement system in diseases Open access cited by 1 patent
Peter Hillmen, Jeff Szer, Ilene Ceil Weitz, Alexander Röth, Britta Höchsmann, Jens Panse, +11 more
407citations -
Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial2022 The Lancet Haematology article Immunology and Microbiology Complement system in diseases Open access
Régis Peffault de Latour, Jeff Szer, Ilene Ceil Weitz, Alexander Röth, Britta Höchsmann, Jens Panse, +12 more
74citations -
Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies2022 American Journal of Nephrology article Immunology and Microbiology Complement system in diseases Open access
Carla Nester, Gerald B. Appel, Andrew S. Bomback, Koenraad Peter Bouman, H. Terence Cook, Erica Daina, +14 more
70citations -
C1q binding to surface-bound IgG is stabilized by C1r 2 s 2 proteases2021 Proceedings of the National Academy of Sciences article Immunology and Microbiology Complement system in diseases Open access
Seline A. Zwarthoff, Kevin Widmer, Annemarie Kuipers, Jürgen Strasser, Maartje Ruyken, Piet C. Aerts, +13 more
62citations -
Impact of first-line use of caplacizumab on treatment outcomes in immune thrombotic thrombocytopenic purpura2023 Journal of Thrombosis and Haemostasis article Immunology and Microbiology Complement system in diseases Open access
Linus Alexander Völker, Jessica Katharina Kaufeld, Gesa Balduin, Lena Merkel, Lucas Kühne, Dennis Alexander Eichenauer, +53 more
55citations -
2021 update of the 2012 ICSH Recommendations for identification, diagnostic value, and quantitation of schistocytes: Impact and revisions2021 International Journal of Laboratory Hematology article Immunology and Microbiology Complement system in diseases Open access
Gina Zini, Giuseppe d’Onofrio, Wendy N. Erber, Szu‐Hee Lee, Yutaka Nagai, Grzegorz Władysław Basak, +1 more
55citations -
Phase 3 randomized COMMODORE 1 trial: Crovalimab versus eculizumab in complement inhibitor‐experienced patients with paroxysmal nocturnal hemoglobinuria2024 American Journal of Hematology article Immunology and Microbiology Complement system in diseases Open access
Phillip Scheinberg, Diego V. Clé, Jin Seok Kim, Erfan Nur, Mustafa Nuri Yenerel, Wilma Barcellini, +15 more
52citations -
The complement alternative pathway in paroxysmal nocturnal hemoglobinuria: From a pathogenic mechanism to a therapeutic target2022 Immunological Reviews review Immunology and Microbiology Complement system in diseases Open access
Antonio Maria Risitano, Camilla Frieri, Eleonora Urciuoli, Luana Marano
52citations -
The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?2021 Journal of Clinical Medicine article Immunology and Microbiology Complement system in diseases Open access
Felix Poppelaars, Bernardo Faria, Wilhelm Schwaeble, Mohamed R. Daha
50citations -
Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains2023 Nature Communications article Immunology and Microbiology Complement system in diseases Open access
Leoni Abendstein, Douwe J. Dijkstra, Rayman T.N. Tjokrodirijo, Peter A. van Veelen, Leendert Adrianus Trouw, Paul J. Hensbergen, +1 more
50citations -
Early Eculizumab Withdrawal in Patients With Atypical Hemolytic Uremic Syndrome in Native Kidneys Is Safe and Cost-Effective: Results of the CUREiHUS Study2022 Kidney International Reports article Immunology and Microbiology Complement system in diseases Open access
Romy N. Bouwmeester, Caroline Duineveld, Kioa Lente Wijnsma, Fréderike J. Bemelman, Joost W van der Heijden, Joanna A.E. van Wijk, +20 more
50citations
Most active Aachen authors
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Jens Panse 10,288 citations overall71 papers
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Régis Peffault de Latour 20,463 citations overall20 papers
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Leendert Adrianus Trouw 13,728 citations overall20 papers
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Antonio Maria Risitano 16,882 citations overall16 papers
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Mohamed R. Daha 31,961 citations overall10 papers
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Cees van Kooten 25,919 citations overall10 papers
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Austin Gladston Kulasekararaj 11,908 citations overall9 papers
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Flore Sicre de Fontbrune 6,345 citations overall8 papers
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Thomas Harry Sharp 3,049 citations overall8 papers
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Mieke F. van Essen 744 citations overall8 papers
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Anja Mühlfeld 2,409 citations overall7 papers
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Paul W.H.I. Parren 32,989 citations overall6 papers
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Haiyu Wang 1,710 citations overall6 papers
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Douwe J. Dijkstra 371 citations overall6 papers
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Leoni Abendstein 215 citations overall6 papers