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Pharmacogenetics and Drug Metabolism Sign in to save
Papers per year
Papers 256
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A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study2023 The Lancet article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jesse Joachim Swen, Cathelijne H. van der Wouden, Lisanne E. N. Manson, H. Abdullah-Koolmees, Kathrin Blagec, Tanja Blagus, +92 more
553citations -
The Concise Guide to PHARMACOLOGY 2023/24: Enzymes2023 British Journal of Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
S P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, +23 more
448citations -
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes2021 British Journal of Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
S P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, +27 more
389citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP3A4 and CYP1A2 and antipsychotics2023 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Lianne Beunk, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Henk‐Jan Guchelaar, +9 more
154citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs2021 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
J. Brouwer, Marga Nijenhuis, Bianca Soree, Henk‐Jan Guchelaar, Jesse Joachim Swen, Ron H. N. van Schaik, +9 more
135citations -
Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for Pharmacogenetics2020 Genes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Laura M. de Jong, Wim Jiskoot, Jesse Joachim Swen, Martijn L. Manson
122citations -
CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations—Implication for Drug Safety, Dosing, and Individualized Therapy2021 Frontiers in Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Immaculate Mbongo Langmia, Katja Susanne Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Mutowembwa Masimirembwa, Julia Stingl
95citations -
Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study2022 Annals of Oncology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Stefanie L. Groenland, Ruben A.G. van Eerden, Kim Westerdijk, Marinda Meertens, Stijn L.W. Koolen, Dirk Jan A. R. Moes, +12 more
82citations -
Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder2020 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sanne Maartje Kloosterboer, Brenda C. M. de Winter, Catrien G. Reichart, Mirjam E. J. Kouijzer, Matthias M. J. de Kroon, Emma van Daalen, +11 more
80citations -
Dutch pharmacogenetics working group (DPWG) guideline for the gene–drug interaction between UGT1A1 and irinotecan2022 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Emma C. Hulshof, Maarten J. Deenen, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, +10 more
80citations -
Toward predicting CYP2D6-mediated variable drug response from CYP2D6 gene sequencing data2021 Science Translational Medicine article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maaike van der Lee, William G. Allard, Rolf H. A. M. Vossen, Renée F. Baak-Pablo, Roberta Menafra, Birgit A. L. M. Deiman, +8 more
80citations -
Individualized Dosing of Fluoropyrimidine‐Based Chemotherapy to Prevent Severe Fluoropyrimidine‐Related Toxicity: What Are the Options?2020 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jonathan Emanuel Knikman, Hans A. J. Gelderblom, Jos H. Beijnen, Annemieke Cats, Henk‐Jan Guchelaar, Linda M. Henricks
78citations -
Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice2021 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Alireza Tafazoli, Henk‐Jan Guchelaar, Wojciech Miltyk, Adam Jacek Kretowski, Jesse Joachim Swen
65citations -
Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone)2021 European Journal of Human Genetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Maja Matić, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer‐Veger, Anne‐Marie Buunk, Elisa J. F. Houwink, +8 more
59citations -
Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study2022 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Mirjam de With, Jonathan Emanuel Knikman, Femke M. de Man, Carin A.T.C. Lunenburg, Linda M. Henricks, André B. P. Kuilenburg, +16 more
58citations -
UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients2022 European Journal of Cancer article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Emma C. Hulshof, Mirjam de With, Femke M. de Man, Geert‐Jan Creemers, Birgit A. L. M. Deiman, Jesse Joachim Swen, +15 more
57citations -
Therapeutic Drug Monitoring and Dosage Adjustments of Immunosuppressive Drugs When Combined With Nirmatrelvir/Ritonavir in Patients With COVID-192022 Therapeutic Drug Monitoring article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Klemens Budde, Teun van Gelder, Stein Bergan, Roland Lawson, Ofelia Noceti, Raman Venkataramanan, +10 more
56citations
Most active Aachen authors
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Jesse Joachim Swen 13,791 citations overall98 papers
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Henk‐Jan Guchelaar 27,269 citations overall81 papers
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Julia Stingl 27,542 citations overall42 papers
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Hans A. J. Gelderblom 55,175 citations overall36 papers
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Katja Susanne Just 1,432 citations overall24 papers
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Maaike van der Lee 573 citations overall23 papers
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Maarten J. Deenen 2,827 citations overall22 papers
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Dirk Jan A. R. Moes 4,889 citations overall21 papers
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Michael Paulzen 4,033 citations overall19 papers
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Stefan Böhringer 14,016 citations overall14 papers
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Teun van Gelder 22,761 citations overall13 papers
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Elisa J. F. Houwink 2,657 citations overall12 papers
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Julian Peter Müller 123 citations overall12 papers
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Arnim Johannes Gaebler 490 citations overall9 papers
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Emma C. Hulshof 228 citations overall9 papers