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Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays101citations
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Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs2024 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Zhen Li, Xiaoling Wang, Josephine M. Janssen, Jin Liu, Francesca Tasca, Rob C. Hoeben, +1 more
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Current capacity and gaps in viral vector manufacturing: a survey of centers associated with CTIWP of EBMT, NXTGEN-hightech, DARE-NL, T2EVOLVE, and GoCART coalition2025 Bone Marrow Transplantation article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Zsolt Sebestyén, Anil K. Deshantri, Simone Punt, Jesús Fernandez Sojo, Sergio Querol, Michael Hudecek, +17 more
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Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment2020 Vaccine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 2 patents
Jerome H. H. V. Custers, Denny Kim, Maarten Leyssen, Marc Gurwith, Frank L. Tomaka, James S. Robertson, +10 more
84citations -
Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning2021 Molecular Therapy article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Adrian Schwarzer, Steven Roger Talbot, Anton Selich, Michael Alexander Morgan, Juliane Wilhelmine Schott, Oliver Dittrich‐Breiholz, +11 more
51citations -
Efficient Viral Transduction in Fetal and Adult Human Inner Ear Explants with AAV9-PHP.B Vectors2022 Biomolecules article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Edward S. A. van Beelen, Wouter H. van der Valk, Thijs O. Verhagen, John C.M.J. de Groot, Margot A. Madison, Wijs Shadmanfar, +5 more
12citations -
The Science is There: Key Considerations for Stabilizing Viral Vector-Based Covid-19 Vaccines2020 Journal of Pharmaceutical Sciences article Medicine SARS-CoV-2 and COVID-19 Research Open access cited by 2 patents
Daan J.A. Crommelin, David B. Volkin, Karin H. Hoogendoorn, Anthony S. Lubiniecki, Wim Jiskoot
61citations -
Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery2021 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Qian Wang, Jin Liu, Josephine M. Janssen, Francesca Tasca, Hailiang Mei, Manuel A.F.V. Gonçalves
44citations -
Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb12021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, C. Henrique Alves, Aat A. Mulder, Charlotte A. Andriessen, Thilo M. Buck, Peter M. J. Quinn, +4 more
14citations -
Administration of an adeno-associated viral vector expressing interferon-β in patients with inflammatory hand arthritis, results of a phase I/II study2021 Osteoarthritis and Cartilage article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Josephina P. M. Vrouwe, Janneke J. M. Meulenberg, Naomi B. Klarenbeek, A. Navas-Cañete, M. Reijnierse, G. Ruiterkamp, +6 more
22citations -
Impact of the Membrane Structure of the Stationary Phase on Steric Exclusion Chromatography (SXC) of Lentiviral Vectors2023 Membranes article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Jennifer J. Labisch, G. Philip Wiese, Karl B. Pflanz, John Linkhorst
2citations -
Poor in vivo transduction of myocardium by lentiviral vectors is likely caused by a post-entry block of transduction2024 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research
Richard G. F. Visser, AMD Vegh, Vincent Portero, J Wang, T Jonker, Max Medina Ramírez, +8 more
0citations -
Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective2022 Journal of Molecular Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Julian Tristan Schwartze, Menzo J E Havenga, Wilfried A.M. Bakker, Angela C. Bradshaw, Stuart A. Nicklin
39citations -
Sixteen capillary electrophoresis applications for viral vaccine analysis2021 Electrophoresis article Engineering Microfluidic and Capillary Electrophoresis Applications Open access cited by 1 patent
Lars Geurink, Ewoud van Tricht, Debbie van der Burg, Gerard Scheppink, Bojana Pajic, Justin Dudink, +1 more
24citations -
Conventional and Tropism-Modified High-Capacity Adenoviral Vectors Exhibit Similar Transduction Profiles in Human iPSC-Derived Retinal Organoids2024 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Andrew J. McDonald, Carmen Gallego, Charlotte A. Andriessen, M A Orlova, Manuel A.F.V. Gonçalves, Jan Wijnholds
8citations -
Phase 1 Safety and Immunogenicity Study of a Respiratory Syncytial Virus Vaccine With an Adenovirus 26 Vector Encoding Prefusion F (Ad26.RSV.preF) in Adults Aged ≥60 Years2020 The Journal of Infectious Diseases article Medicine Respiratory viral infections research cited by 9 patents
Kristi L. Williams, Arangassery Rosemary Bastian, Robert Feldman, Edmund V Ekoka Omoruyi, Els De Paepe, Jenny Hendriks, +6 more
111citations -
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 5 patents
Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Stefan Bernhard Thalhammer, David Manuel Mittas, Nina Karguth, Dina Yehia Otify, +15 more
83citations