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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids2020 Cell Systems article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Jeremy J. Velazquez, Ryan LeGraw, Farzaneh Moghadam, Yuqi Tan, Jacquelyn A. Kilbourne, Joseph C. Maggiore, +8 more
110citations -
Rethinking organoid technology through bioengineering2020 Nature Materials article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 2 patents
Elena Garreta, Roger Dale Kamm, Susana M. Chuva de Sousa Lopes, Madeline A. Lancaster, Ron Weiss, Xavier Trepat, +2 more
337citations -
Engineering multicellular living systems—a Keystone Symposia report2022 Annals of the New York Academy of Sciences article Engineering 3D Printing in Biomedical Research Open access
Jennifer Cable, Paola Arlotta, Kevin Kit Parker, Alex J. Hughes, Katharine Goodwin, Christine L. Mummery, +19 more
6citations -
Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss2023 Nature Communications article Medicine Hepatocellular Carcinoma Treatment and Prognosis Open access
Laura Rüland, Francesco Andreatta, Simone Massalini, Susana M. Chuva de Sousa Lopes, Hans C. Clevers, Delilah F. G. Hendriks, +1 more
34citations -
Biomaterials in organoid research: current state and future directions2026 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Hydrogels: synthesis, properties, applications Open access
Laura Klasen, Ramin Nasehi, Lennart Selzener, Laura De Laporte
0citations -
Large-scale engineering of hiPSC-derived nephron sheets and cryopreservation of their progenitors2022 Stem Cell Research & Therapy article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Loes E. Wiersma, M. Cristina Avramut, Ellen Lievers, Ton J. Rabelink, Cathelijne W. van den Berg
14citations -
Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids2020 Advanced Healthcare Materials article Materials Science Advanced Cellulose Research Studies Open access cited by 2 patents
Melanie Krüger, Loes A. Oosterhoff, Monique E. van Wolferen, Simon Schiele, Andreas Walther, Niels Geijsen, +4 more
92citations -
High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds2022 Journal of Cellular and Molecular Medicine article Medicine Tissue Engineering and Regenerative Medicine Open access
Melanie Krüger, Roos‐Anne Samsom, Loes A. Oosterhoff, Monique E. van Wolferen, H.S. Kooistra, Niels Geijsen, +5 more
11citations -
Mini-hearts for disease modeling and drug testing – process optimization versus biological functionality2026 Frontiers in Bioengineering and Biotechnology article Medicine Tissue Engineering and Regenerative Medicine Open access
Jana Hecking, Mariel Cano-Jorge, R. C. Passier, José M. Rivera‐Arbeláez
0citations -
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids2023 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Maarten H. Geurts, Shashank Gandhi, Matteo Boretto, Ninouk Akkerman, Lucca L. M. Derks, Gijs J. F. van Son, +10 more
65citations -
Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model2021 ACS Biomaterials Science & Engineering article Medicine Lymphatic System and Diseases Open access
Nicola C. Frenkel, Susanna Poghosyan, Carmen Rubio Alarcon, Silvia Bonilla García, Karla C. S. Queiroz, Lotte van den Bent, +5 more
38citations -
A gastruloid model of the interaction between embryonic and extra-embryonic cell types2022 Journal of Tissue Engineering article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access
Noémie M. L. P. Bérenger-Currias, Maria Mircea, Esmée Adegeest, Patrick R. van den Berg, Marleen Feliksik, Mazène Hochane, +3 more
26citations -
Supra- and sub-threshold intracellular-like recording of 2D and 3D neuronal networks using nanopillar electrode arrays2024 Microsystems & Nanoengineering article Neuroscience Neuroscience and Neural Engineering Open access
Shivani Shukla, Joshua L. Schwartz, Wen Mai Wong, Vrund Patel, Chichi Onwuasoanya, S.-Y. Chen, +7 more
14citations -
Scalable production of tissue-like vascularized liver organoids from human PSCs2023 Experimental & Molecular Medicine article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 5 patents
Sean Philip Harrison, Richard Siller, Yoshiaki Tanaka, María Eugenia Chollet, María Eugenia de la Morena‐Barrio, Yangfei Xiang, +29 more
120citations -
Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Josse A. Depla, Marina Sogorb-González, Lance Mulder, Vivi Majella Heine, Pavlina S. Konstantinova, Sander J. van Deventer, +4 more
53citations -
Macrophage-augmented intestinal organoids model virus-host interactions in enteric viral diseases and facilitate therapeutic development2025 Nature Communications article Medicine Viral gastroenteritis research and epidemiology Open access
Guige Xu, Yining Wang, Theano Tsikari, Qin Fang, Francijna E. van den Hil, Patrick P.C. Boor, +13 more
20citations -
Vascularized 3D Human Skin Models in the Forefront of Dermatological Research2024 Advanced Healthcare Materials article Engineering 3D Printing in Biomedical Research Open access
Rahul Rimal, Saradaprasan Muduli, Prachi Bharat Desai, Andrea Bonnin Márquez, Martin Möller, Ilia Platzman, +2 more
46citations