Papers matching “hepatic gene expression” 139
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A hierarchical dynamic model used for investigating feed efficiency and its relationship with hepatic gene expression in APOE*3‐Leiden.CETP mice2021 Physiological Reports article Biochemistry, Genetics and Molecular Biology Nutrition, Genetics, and Disease Open access
Xiang Zhang, Yared Paalvast, Yanan Wang, Patrick C.N. Rensen, Albert Kornelis Groen
4citations -
Mendelian randomization while jointly modeling cis genetics identifies causal relationships between gene expression and lipids2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Adriaan van der Graaf, Annique Claringbould, Antoine Rimbert, Bastiaan T. Heijmans, Peter A.C. ’t Hoen, Joyce B. J. van Meurs, +6 more
61citations -
Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl82024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Steven J. Kunnen, Emma Arnesdotter, Christian Tobias Willenbockel, Mathieu Vinken, Bob van de Water
0citations -
Qualitative and quantitative concentration-response modelling of gene co-expression networks to unlock hepatotoxic mechanisms for next generation chemical safety assessment_Suppl22024 ALTEX article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Steven J. Kunnen, Emma Arnesdotter, Christian Tobias Willenbockel, Mathieu Vinken, Bob van de Water
0citations -
Systematic comparison of temporal transcriptional responses to hepatotoxicants in primary human hepatocytes and HepaRG cells using concentration-response modelling of gene co-expression networks2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Steven J. Kunnen, Emma Arnesdotter, Christian Tobias Willenbockel, Mathieu Vinken, Bob van de Water
0citations -
Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Lea Berger, Cyrill Géraud, +18 more
0citations -
Seed- and leaf-based expression of FGF21-transferrin fusion proteins for oral delivery and treatment of non-alcoholic steatohepatitis2022 Frontiers in Plant Science article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access
Hsuan-Wu Hou, Christopher A. Bishop, Jana Huckauf, Inge Broer, Susanne Klaus, Henrik Nausch, +1 more
5citations -
Exceptional Uptake, Limited Protein Expression: Liver Macrophages Lost in Translation of Synthetic mRNA2025 Advanced Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Cheng Lin, Adrian Kuzmanović, Nan Wang, Liangliang Liao, Sabrina Ernst, Christian Penners, +16 more
6citations -
Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes2021 Toxicology in Vitro article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Bas ter Braak, Marije Niemeijer, Ruben Boon, Celine Parmentier, Audrey Baze, Lysiane Richert, +4 more
14citations -
SAHA increases chaperone expression and reduces Z-alpha-1-antitrypsin polymers in a patient specific iPSC-based liver model for alpha-1-antitrypsin deficiency2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Nina Graffmann, Rabea Hokamp, Christiane Loerch, Malin Fromme, Wasco Wruck, Pavel Strnad, +1 more
0citations -
PRMT5 inhibition induces pro‐inflammatory macrophage polarization and increased hepatic triglyceride levels without affecting atherosclerosis in mice2023 Journal of Cellular and Molecular Medicine article Biochemistry, Genetics and Molecular Biology Cancer-related gene regulation Open access
Yiheng Zhang, Robin A.F. Verwilligen, Miranda Van Eck, Menno Hoekstra
15citations