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Mining a human transcriptome database for chemical modulators of NRF22020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
John P. Rooney, Brian N. Chorley, Steven W. Hiemstra, Steven Wink, Xuting Wang, Douglas A. Bell, +2 more
54citations -
Luteolin Induces Nrf2 Activity in C2C12 Cells: Implications for Muscle Health2025 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Frank Suhr, Thomas Pufe, Christoph Jan Wruck, Athanassios Fragoulis
9citations -
Platelet‐Released Growth Factors (PRGFs) Activate NRF2‐ARE and Modulate Inflammatory Response in an NRF2‐Dependent Manner in Primary Human Keratinocytes2025 Journal of Cosmetic Dermatology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Mersedeh Tohidnezhad, Athanassios Fragoulis, Andreas U. Bayer, Hannes Klump, Jens Malte Baron, Thomas Pufe
2citations -
Die KEAP1/NRF2 Achse in Hepatozyten kontrolliert die Fibro- und Karzinogenese bei chronischen Leberkrankungen2020 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Antje Mohs, Tim Otto, KM Schneider, Mona Peltzer, Mark V. Boekschoten, CH Holland, +6 more
0citations -
Mapping the dynamics of Nrf2 antioxidant and NFκB inflammatory responses by soft electrophilic chemicals in human liver cells defines the transition from adaptive to adverse responses2022 Toxicology in Vitro article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Bas ter Braak, Janna E. Klip, Steven Wink, Steven W. Hiemstra, Sarah Lucy Cooper, A. Middleton, +2 more
8citations -
Deciphering the quantitative relationship between NRF2 and SRXN1 through semi-mechanistic computational modeling2025 Toxicology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Raju Prasad Sharma, Liesanne Wolters, Bas ter Braak, Marije Niemeijer, Andrew White, Bob van de Water, +2 more
1citations -
Keap1 Deletion Rescues Cell Death Associated With Gpx4 Loss in Hepatocytes During Acute Liver Injury2025 Liver International article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Leticia Colyn, Julia Grube, Chaochao Wang, Mark Kühnel, Jörg Reinders, Karolina Edlund, +4 more
6citations -
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models2022 Archives of Toxicology article Biochemistry, Genetics and Molecular Biology Carcinogens and Genotoxicity Assessment Open access
Liliana Capinha, Yaran Zhang, Anna‐Katharina Holzer, Anna‐Katharina Ückert, Melinda Zana, Giada Carta, +8 more
12citations -
Itaconate enhances oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Naziia Kurmasheva, Aida Said, Boaz Wong, Alena Kress, Zhenlong Liu, Chen Wang, +34 more
0citations -
Effect of Methysticin on osteoblast function under oxidative stress through Nrf2/HO-1 signaling pathway: in vitro study2021 Osteologie/Osteology conference-paper Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases
Yusuke Kubo, H. Burkhard Dick, Mersedeh Tohidnezhad, Athanassios Fragoulis, Holger Jahr, CJ Wruck, +1 more
0citations -
NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA2022 Antioxidants article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Anandhi Rajendiran, Sudheendra Hebbar Subramanyam, Patricia Klemm, Vera Jankowski, Jorg van Loosdregt, Sebastiaan J. Vastert, +4 more
16citations -
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Dorotée Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke S. van Bergen, +26 more
106citations -
Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts2021 International Journal of Molecular Sciences article Medicine Liver Disease Diagnosis and Treatment Open access
Sreepradha Eswaran, Anshu Babbar, Hannah K. Drescher, Thomas C. A. Hitch, Thomas Clavel, Moritz Muschaweck, +5 more
2citations -
The NRF2/KEAP1 pathway in hepatocytes controls fibro- and carcinogenesis in chronic liver disease2020 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Antje Mohs, Tobias Otto, KM Schneider, MT Peltzer, Mark V. Boekschoten, Christian Trautwein
0citations -
Pharmacological effects of methysticin and L-sulforaphane through the Nrf2/ARE signaling pathway in MLO-Y4 osteocytes: in vitro study2024 Annals of Anatomy - Anatomischer Anzeiger article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Maja Charlotte Dittmar, Mersedeh Tohidnezhad, Athanassios Fragoulis, Annette Bücker, M. Stein, Thomas Pufe, +1 more
3citations -
Hydrogen sulfide as a therapeutic gas: challenges and opportunities in precision medicine2026 Medical Gas Research article Biochemistry, Genetics and Molecular Biology Sulfur Compounds in Biology Open access
Okechukwu Paul-Chima Ugwu, Esther Ugo Alum, Val Hyginus Udoka Eze, Mariam Basajja
0citations
20 results