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Keap1 Deletion Rescues Cell Death Associated With Gpx4 Loss in Hepatocytes During Acute Liver Injury2025 Liver International article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Leticia Colyn, Julia Grube, Chaochao Wang, Mark Kühnel, Jörg Reinders, Karolina Edlund, +4 more
6citations -
p62/SQSTM1-KEAP1 complex prevents clearance of ubiquitinated Z alpha-1 antitrypsin and aggravates liver proteotoxicity2026 Journal of Biological Chemistry article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Nunzia Pastore, Sergio Attanasio, Francesco Annunziata, Claudia D’Agostino, Veronica Maffia, Teresa Giuliano, +12 more
0citations -
Dynamic modeling of Nrf2 pathway activation in liver cells after toxicant exposure2022 Scientific Reports article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Steven W. Hiemstra, Mirjam Fehling-Kaschek, Isoude A. Kuijper, Luc J. M. Bischoff, Lukas S. Wijaya, Marcus Rosenblatt, +7 more
31citations -
Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts2021 International Journal of Molecular Sciences article Medicine Liver Disease Diagnosis and Treatment Open access
Sreepradha Eswaran, Anshu Babbar, Hannah K. Drescher, Thomas C. A. Hitch, Thomas Clavel, Moritz Muschaweck, +5 more
2citations -
Mining a human transcriptome database for chemical modulators of NRF22020 PLoS ONE article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
John P. Rooney, Brian N. Chorley, Steven W. Hiemstra, Steven Wink, Xuting Wang, Douglas A. Bell, +2 more
54citations -
Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis2020 Journal of Hepatology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Antje Mohs, Tobias Otto, Kai Markus Schneider, Mona Peltzer, Mark V. Boekschoten, Christian H. Holland, +7 more
142citations -
The role of Nrf2/Keap1 in chondral ossification and bone growth.2025 Annals of Anatomy - Anatomischer Anzeiger article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases
Mersedeh Tohidnezhad, Yusuke Kubo, Naiem Alwafai, Athanassios Fragoulis, Alexander Slowik, Christoph Jan Wruck, +1 more
0citations -
Effect of Prooxidative Natural Products: Comparison of the OSI1 (YKL071w) Promoter Luciferase Construct from Yeast with an Nrf2/Keap Reporter System2020 Applied Sciences article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Ivan Schlembach, Andreas Uebachs, Tim Caspers, Athanassios Fragoulis, Alan John Slusarenko, Martin C. H. Gruhlke
1citations -
Luteolin Induces Nrf2 Activity in C2C12 Cells: Implications for Muscle Health2025 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Frank Suhr, Thomas Pufe, Christoph Jan Wruck, Athanassios Fragoulis
9citations -
Hydrogen sulfide as a therapeutic gas: challenges and opportunities in precision medicine2026 Medical Gas Research article Biochemistry, Genetics and Molecular Biology Sulfur Compounds in Biology Open access
Okechukwu Paul-Chima Ugwu, Esther Ugo Alum, Val Hyginus Udoka Eze, Mariam Basajja
0citations -
Plant-Derived Protein Hydrolysates and Bioactive Peptides for Restoring Gut Health in Undernutrition: A Scoping Review of Intestinal Barrier Protection, Inflammatory Signaling, and Oxidative Stress Regulation2026 Nutrients article Biochemistry, Genetics and Molecular Biology Protein Hydrolysis and Bioactive Peptides Open access
Asad Abbas, Muhammad Khurram Afzal, Fahid Nazir, Ralf Weiskirchen, Muhammad Bilal, Ghalia Arshad, +5 more
0citations
23 results