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Identification of mitochondrial toxicants by combined in silico and in vitro studies – A structure-based view on the adverse outcome pathway2020 Computational Toxicology article Computer Science Computational Drug Discovery Methods Open access
Florentina Troger, Johannes Delp, Melina Funke, Wanda van der Stel, Claire Colas, Marcel Leist, +2 more
22citations -
OC 60.2 Population-Based Prevalence and Mutational Landscape of Von Willebrand Disease using Large-Scale Genetic Databases2023 Research and Practice in Thrombosis and Haemostasis article Medicine Platelet Disorders and Treatments Open access
Omid Seidizadeh, Andrea Cairo, Luciano Baronciani, Luca V. C. Valenti, Flora Peyvandi
0citations -
AlphaFold‐Guided Discovery of an Overlapping MYC/Miz‐1 Interface Enables Peptidomimetic Disruption of MYC/MAX2025 ChemMedChem article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Brecht D. Ellenbroek, Amardhiko S. S. Tirtosentono, Sebastian J. Pomplun
2citations -
The integrated Lei‐CNS PBPK‐PD model effectively predicts clozapine brain disposition and D 2 receptor occupancy in humans2026 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Mengxu Zhang, Thomas I.F.H. Cremers, Vivi Rottschäfer, Elizabeth C. M. de Lange
0citations -
Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia2026 Genome biology article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Lieke Michielsen, Justine Hsu, Anoushka Joglekar, Natan Belchikov, Marcel J. T. Reinders, Hagen Tilgner, +1 more
0citations -
Evaluating BindCraft for Generative Design of High-Affinity Peptides2025 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis Open access
Mike Filius, Thanasis Patsos, Hugo Minnee, Jingming Liu, Monika T. Gnatzy, Ramon S. M. Rooth, +5 more
18citations -
Concentration‐Dependent Reactivity Profiles of a Human Monoclonal Antibody Recognising HLA‐DQB1*04/05/06 and at Reduced Intensities to DQB1*03 Antigens2026 HLA article Biochemistry, Genetics and Molecular Biology vaccines and immunoinformatics approaches Open access
Shi‐Yuan Meng, Ujjwala Singh, Naiiry Petrosyan, Fred Quiroz, Xiaoliang Yao, Than Than Han, +12 more
0citations -
COMMBAT: a web platform for exploring expression control of biosynthetic gene clusters2026 Nucleic Acids Research article Medicine Microbial Natural Products and Biosynthesis Open access
Silvia Ribeiro Monteiro, Augustin Rigolet, Clément Jeunehomme, Julianne Gathot, Yasmine Kerdel, Hannah E. Augustijn, +3 more
2citations -
Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations2021 Journal of Pharmacokinetics and Pharmacodynamics article Neuroscience Barrier Structure and Function Studies Open access
Mohammed A. A. Saleh, Chi Fong Loo, Jeroen Elassaiss‐Schaap, Elizabeth C. M. de Lange
43citations -
Large-scale functional inference for skin-expressing lncRNAs using expression and sequence information2023 JCI Insight article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Matthew T. Patrick, Sutharzan Sreeskandarajan, Alanna Shefler, Rachael Wasikowski, Mrinal K. Sarkar, Jiahan Chen, +10 more
8citations -
Hydrophobic interaction chromatography (HIC) isotherm incorporating salt-dependent water activity enhances model-based analysis of protein elution profiles2025 Journal of Chromatography A article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Ronald Jäpel, Matthias Knödler, Eric von Lieres, Johannes F. Buyel
3citations