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PILOT-GM-VAE: Patient-Level Analysis of single cell Disease Atlas with Optimal Transport of Gaussian Mixture Variational Autoencoders2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Mehdi Joodaki, Mina Shaigan, James Shiniti Nagai, Tiago Maié, Christoph Kuppe, Ivan G. Costa
0citations -
An in-depth comparison of linear and non-linear joint embedding methods for bulk and single-cell multi-omics2023 Briefings in Bioinformatics article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Stavros Makrodimitris, Bram Pronk, Tamim Abdelaal, Marcel J. T. Reinders
12citations -
A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast2020 eLife article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Sara N. Mouton, David J. Thaller, Matthew M. Crane, Irina L. Rempel, Owen T Terpstra, Anton Steen, +4 more
52citations -
Data from "Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer"0citations
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Single Cell Analysis of Regions of Interest (SCARI) using a novel photoswitchable tag2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anne M. van der Leun, Mirjam E. Hoekstra, Luuk Reinalda, Colinda L. G. J. Scheele, Mireille Toebes, Michel J. van de Graaff, +10 more
1citations -
Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq data2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 1 patent
Daniel Dimitrov, Dénes Türei, Martín Garrido‐Rodríguez, Paul L Burmedi, James Shiniti Nagai, Charlotte Boys, +7 more
670citations -
Experimental and computational technologies to dissect the kidney at the single-cell level2020 Nephrology Dialysis Transplantation article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Christoph Kuppe, Javier Perales-Patón, Julio Sáez-Rodríguez, Rafael Kramann
12citations -
Defining the variety of cell types in developing and adult human kidneys by single-cell RNA sequencing2021 npj Regenerative Medicine article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anika Schumacher, Maarten B. Rookmaaker, Jaap A. Joles, Rafael Kramann, Tri Quang Nguyen, Martijn van Griensven, +1 more
60citations -
Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Daniel Osorio, Anna Capasso, S. Gail Eckhardt, Uma P. Giri, Alexander J. Somma, Todd M. Pitts, +8 more
2citations -
Single Cell Analysis of Reversibility of the Cell Death Program in Ethanol-Treated Neuronal PC12 Cells2022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Cell death mechanisms and regulation Open access
Wenting You, Tos T. J. M. Berendschot, Kèvin Knoops, Marc A. M. J. van Zandvoort, Carroll A.B. Webers, Chris P.M. Reutelingsperger
11citations -
scMEGA: Single-cell Multiomic Enhancer-based Gene Regulatory Network Inference2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Zhijian Li, James Shiniti Nagai, Christoph Kuppe, Rafael Kramann, Ivan G. Costa
0citations -
Data-based stochastic modeling reveals sources of activity bursts in single-cell TGF-β signaling2022 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Niklas Kolbe, Lorenz Hexemer, Lukas-Malte Bammert, Alexander Loewer, Mária Lukáčová-Medviďová, Stefan Legewie
9citations -
Fast model-free standardization and integration of single-cell transcriptomics data2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yang Xu, Rafael Kramann, Rachel Patton McCord, Sikander Hayat
0citations -
De-novoreconstruction and identification of transcriptional gene regulatory network modules differentiating single-cell clusters2023 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Mhaned Oubounyt, Maria L. Elkjaer, Tanja Laske, Alexander G. B. Grønning, Marcus Johannes Moeller, Jan Baumbach
8citations -
On the benchmarking of clustering algorithms and hyperparameter influence for cell type detection in single-cell RNA sequencing data2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Aleksandra Szmigiel, Ivan G. Costa, Ricardo J. G. B. Campello
2citations