Papers matching “predictive toxicity models” 126
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National indication protocol for proton radiotherapy in esophageal cancer patients in the Netherlands2025 Radiotherapy and Oncology article Medicine Esophageal Cancer Research and Treatment Open access
Christina T. Muijs, Yvonne L.B. Klaver, Joost J.M.E. Nuyttens, Irene M. Lips, Karin Müller, G. Ebrahimi, +4 more
4citations -
Review and Prospects on the Ecotoxicity of Mixtures of Nanoparticles and Hybrid Nanomaterials2022 Environmental Science & Technology article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Fan Zhang, Zhuang Wang, Willie J.G.M. Peijnenburg, Martina G. Vijver
120citations -
Addressing the Data Scarcity Problem in Ecotoxicology via Small Data Machine Learning Methods2025 Environmental Science & Technology article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Ying Wang, Yunchi Zhou, Yinghao Cheng, Xiaoli Zhao, Willie J.G.M. Peijnenburg, Martina G. Vijver, +3 more
55citations -
Integration of in vitro and in silico approaches enables prediction of drug-induced liver injury2026 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
René Geci, Ahenk Zeynep Sayin, Stephan Schaller, Lars Kuepfer
5citations -
What is the ecotoxicity of a given chemical for a given aquatic species? Predicting interactions between species and chemicals using recommender system techniques2023 SAR and QSAR in environmental research article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Jordi Minnema, Pim N.H. Wassenaar, Emiel Rorije, Willie J.G.M. Peijnenburg
15citations -
A novel approach for pharmacological substantiation of safety signals using plasma concentrations of medication and administrative/healthcare databases: A case study using Danish registries for an FDA warning on lamotrigine2023 Pharmacological Research article Pharmacology, Toxicology and Pharmaceutics Pharmacovigilance and Adverse Drug Reactions Open access
Wenyi Wang, Vera Battini, Carla Carnovale, Raymond Noordam, Ko Willems van Dijk, Kristian Hay Kragholm, +3 more
9citations -
Identification of mitochondrial toxicants by combined in silico and in vitro studies – A structure-based view on the adverse outcome pathway2020 Computational Toxicology article Computer Science Computational Drug Discovery Methods Open access
Florentina Troger, Johannes Delp, Melina Funke, Wanda van der Stel, Claire Colas, Marcel Leist, +2 more
22citations -
Wisdom of Crowds for Supporting the Safety Evaluation of Nanomaterials2025 Environmental Science & Technology article Materials Science Nanoparticles: synthesis and applications Open access
Laura Aliisa Saarimäki, Michele Fratello, Giusy del Giudice, Emanuele Di Lieto, Antreas Afantitis, Harri Tapio Alenius, +21 more
3citations -
AI-aided chronic mixture risk assessment along a small European river reveals multiple sites at risk and pharmaceuticals being the main risk drivers2025 Environment International article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Fabian G. Weichert, Pedro A. Inostroza, Jörg Ahlheim, Thomas Backhaus, Werner Brack, Mario Brauns, +4 more
15citations -
Computational modelling identifies primary mediators of crosstalk between DNA damage and oxidative stress responses2025 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Elsje J Burgers, Raju P. Sharma, Carl Joshua Eugenio, Muriel M. Heldring, Lukas S. Wijaya, Bob van de Water, +1 more
3citations -
Double trouble: The synergistic threat of environmental stressors and pesticide mixtures2025 Journal of Hazardous Materials article Environmental Science Environmental Toxicology and Ecotoxicology Open access
Naeem Shahid, Ayesha Siddique, Martin Krayer Von Krauss, Alexander Böhme, Werner Brack, Annika Jahnke, +1 more
9citations -
Automated image analysis system for studying cardiotoxicity in human pluripotent stem cell-Derived cardiomyocytes2020 BMC Bioinformatics article Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Lu Cao, Andries D. van der Meer, Fons J. Verbeek, Robert C. J. J. Passier
14citations -
Revisiting Acyclovir Dosing for Adult Viral Encephalitis Using a Full Bayesian LeiCNS PBPK Modeling Approach2025 Clinical Pharmacokinetics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Tingjie Guo, Martijn L. Manson, Anne‐Grete Märtson, Jacob Bodilsen, Elizabeth C. M. de Lange
3citations -
Prediction of dose reductions and impact of reduced starting doses of CDK4 /6i on effectiveness in HR ‐positive/ HER2 ‐negative metastatic breast cancer: Real‐world data from the OPAL registry
Patrick Marschner, Kai G. Ringwald, Marc Thill, Mark‐Oliver Zahn, Anja Welt, Arnd Nusch, +14 more
4citations -
In Search of Beautiful Molecules: A Perspective on Generative Modeling for Drug Design2025 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Remco L. van den Broek, Shivam Patel, Gerard J. P. van Westen, Willem Jespers, Woody Sherman
38citations -
Breast Cancer Index Predicts Extended Endocrine Benefit to Individualize Selection of Patients with HR+ Early-stage Breast Cancer for 10 Years of Endocrine Therapy2020 Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access cited by 1 patent
Iris Noordhoek, Kai Treuner, Hein Putter, Yi Zhang, Jenna Wong, Elma Meershoek‐Klein Kranenbarg, +4 more
133citations -
Population Pharmacokinetic and Pharmacogenetic Analysis of Mitotane in Patients with Adrenocortical Carcinoma: Towards Individualized Dosing2020 Clinical Pharmacokinetics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anyue Yin, Madeleine H. T. Ettaieb, Jesse Joachim Swen, Liselotte van Deun, Thomas M. A. Kerkhofs, R.J.H.M. van der Straaten, +11 more
13citations -
Implementation of a Human Renal Proximal Tubule on a Chip for Nephrotoxicity and Drug Interaction Studies2021 Journal of Pharmaceutical Sciences article Engineering 3D Printing in Biomedical Research Open access
Marianne K. Vormann, Jelle Vriend, Henriëtte L. Lanz, Linda Gijzen, Angelique van den Heuvel, Simon Hutter, +17 more
88citations