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Perspective: Implications of Ligand–Receptor Binding Kinetics for Therapeutic Targeting of G Protein-Coupled Receptors2020 ACS Pharmacology & Translational Science article Biochemistry, Genetics and Molecular Biology Receptor Mechanisms and Signaling Open access
Wijnand J. C. van der Velden, Laura H. Heitman, METTE MARIE ROSENKILDE
67citations -
AAV-mediated gene augmentation therapy of CRB1 patient-derived retinal organoids restores the histological and transcriptional retinal phenotype2023 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, Xuefei Lu, Charlotte A. Andriessen, Ioannis Moustakas, Thilo M. Buck, Christiaan H. Arendzen, +4 more
46citations -
Targeting Cholesterol Metabolism as Efficient Antiviral Strategy Against the Hepatitis E Virus2021 Cellular and Molecular Gastroenterology and Hepatology article Medicine Hepatitis Viruses Studies and Epidemiology Open access
Mirco Glitscher, Kathrin Woytinek, Denna Tabari, Catharina Scholl, Julia Stingl, Evelyn Seelow, +2 more
46citations -
Together is Better: mRNA Co‐Encapsulation in Lipoplexes is Required to Obtain Ratiometric Co‐Delivery and Protein Expression on the Single Cell Level2021 Advanced Science article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Heyang Zhang, Jeroen Bussmann, Florian Hendric Huhnke, Joke Devoldere, An‐Katrien Minnaert, Wim Jiskoot, +6 more
37citations -
Multicompartment Polyion Complex Micelles Based on Triblock Polypept(o)ides Mediate Efficient siRNA Delivery to Cancer‐Associated Fibroblasts for Antistromal Therapy of Hepatocellular Carcinoma2024 Advanced Materials article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Paul M. Schneider, Heyang Zhang, Leon Simić, Barbara Schrörs, Özlem Akilli‐Öztürk, Lin Jian, +14 more
33citations -
Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients2020 Antiviral Research article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Yingying Dou, Diahann T. S. L. Jansen, Aniek van den Bosch, Robert Auke de Man, Nadine van Montfoort, Can Araman, +6 more
21citations -
Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells2023 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, +1 more
19citations -
Cell-penetrating peptide-conjugated copper complexes for redox-mediated anticancer therapy2022 Frontiers in Pharmacology article Medicine Metal complexes synthesis and properties Open access
Quim Peña, Sergi Rodríguez-Calado, Ariane Jalila Simaan, Mercè Capdevila, Pau Bayón, Òscar Palacios, +2 more
17citations -
Impact of Stimuli-Responsiveness on the mRNA Delivery Efficiency of Low-Generation Dendrimer Nanogels2025 Biomacromolecules article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery
Xianghao Xiao, Yue Gao, Yiyang Jia, Mingwu Shen, Andrij Pich, Xiangyang Shi
10citations -
Cationic pH-sensitive liposomes as tuberculosis subunit vaccine delivery systems: Effect of liposome composition on cellular innate immune responses2024 International Immunopharmacology article Medicine Tuberculosis Research and Epidemiology Open access
M.M. Szachniewicz, Krista E. van Meijgaarden, E Kavrik, Wim Jiskoot, Joke A. Bouwstra, Mariëlle C. Haks, +2 more
5citations -
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review2026 Frontiers in Drug Delivery review Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Okechukwu Paul-Chima Ugwu, Fabian Chukwudi Ogenyi, Mariam Basajja, Chinyere Nneoma Ugwu, Mundu M. Mustafa, Michael Ben Okon
5citations -
Complex structural variation and nonsense variant in trans cause VPS50-related disorder2024 Journal of Medical Genetics article Biochemistry, Genetics and Molecular Biology Genomics and Rare Diseases
Laura Hecher, Esther Gorski-Alberts, Matthias Begemann, J. Herwig, Eva Lausberg, Georg Hillebrand, +4 more
5citations -
Dendrimer-based nanoplatforms for enhanced mRNA delivery: From rational structural design to formulation strategies2025 Advanced Interventional Materials article Materials Science Dendrimers and Hyperbranched Polymers Open access
Xianghao Xiao, Yiyang Jia, Mingwu Shen, Andrij Pich, Xiangyang Shi
4citations -
Molecular Tuning of Cyanine 5 Dyes to Improve the Pharmacokinetic Profile of Nanobody-Based Fluorescent Tracers2025 ACS Pharmacology & Translational Science article Medicine Radiopharmaceutical Chemistry and Applications Open access
Łukasz Mateusiak, Dora Mugoli Chigoho, Sam Floru, Sofie Pollenus, Pieterjan Debie, Danny M. van Willigen, +2 more
3citations -
1-Phosphatidylinositol 3-Phosphate 5-Kinase Inhibition by Apilimod Promotes an Adipocyte-Like Vascular Smooth Muscle Cell Phenotype and Prevents Arterial Calcification2026 Circulation Research article Biochemistry, Genetics and Molecular Biology Dermatological and Skeletal Disorders
Nicolas Hense, Andrea Gorgels, Bilal Mir, Emiel P. C. van der Vorst, Guillaume Falgayrac, Mara Terliesner, +16 more
2citations -
Virotrap Reveals Salmonella SopB as A Ubiquitinated Cargo for Host ESCRT-02025 bioRxiv (Cold Spring Harbor Laboratory) preprint Agricultural and Biological Sciences Salmonella and Campylobacter epidemiology Open access
Margaux De Meyer, Annick Verhee, Hanna Grzesik, Delphine De Sutter, Jon Huyghe, Louis Delhaye, +8 more
1citations