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Adverse Effects of Oxidative Stress on Bone and Vasculature in Corticosteroid-Associated Osteonecrosis: Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 in Cytoprotection
Yusuke Kubo, Wolf Drescher, Athanassios Fragoulis, Mersedeh Tohidnezhad, Holger Jahr, Matthias Gatz, +5 more
38citations -
Betaine ameliorates doxorubicin‐induced cardiomyopathy by inhibiting oxidative stress, inflammation, and fibrosis through the modulation of AMPK /Nrf2/ TGF ‐β expression
Sumeet Kumar Singh, Poonam Yadav, Sampat Singh Tanwar, Abhishek Sherawat, Amit Khurana, Jasvinder Singh Bhatti, +1 more
24citations -
Upregulation of CCL7, CCL20, CXCL2, IL-1β, IL-6 and MMP-9 in Skin Samples of PCB Exposed Individuals—A Preliminary Study2021 International Journal of Environmental Research and Public Health article Environmental Science Toxic Organic Pollutants Impact Open access
Marike M. Leijs, Katharina Fietkau, Hans Friedrich Merk, Thomas Schettgen, Thomas Kraus, André Esser
6citations -
Computational modelling identifies primary mediators of crosstalk between DNA damage and oxidative stress responses2025 PLoS Computational Biology article Biochemistry, Genetics and Molecular Biology Genomics, phytochemicals, and oxidative stress Open access
Elsje J Burgers, Raju P. Sharma, Carl Joshua Eugenio, Muriel M. Heldring, Lukas S. Wijaya, Bob van de Water, +1 more
3citations -
Balance Between EGF/STAT1 and IFNγ/NRF2 Signaling Controls ECM1 Expression and Determines Hepatic Homeostasis versus Chronic Liver Disease2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Liver physiology and pathology Open access
Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Lea Berger, Cyrill Géraud, +18 more
0citations -
Possible Association of Nrf2/ARE and NFκB Response to Osteoblast Function in Spheroid Culture Induced by Low-Intensity Pulsed Ultrasound (LIPUS)2025 Ultrasound in Medicine & Biology article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases Open access
Yusuke Kubo, Anna Theresa Tangarife Bodensiek, Sebastian Lippross, Marek Weiler, Nina Reinhardt, Matias de la Fuente, +11 more
0citations -
Itaconate enhances oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways2023 Research Square preprint Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Naziia Kurmasheva, Aida Said, Boaz Wong, Alena Kress, Zhenlong Liu, Chen Wang, +34 more
0citations -
Iron accumulation induces oxidative stress, while depressing inflammatory polarization in human iPSC-derived microglia2022 Stem Cell Reports article Neuroscience Neuroinflammation and Neurodegeneration Mechanisms Open access
Boyd Kenkhuis, Michelle van Eekeren, David A. Parfitt, Yavuz Ariyürek, Poulomi Banerjee, Josef Priller, +2 more
70citations -
Biophysical Modulation of the Mitochondrial Metabolism and Redox in Bone Homeostasis and Osteoporosis: How Biophysics Converts into Bioenergetics2021 Antioxidants article Biochemistry, Genetics and Molecular Biology Bone Metabolism and Diseases Open access
Feng‐Sheng Wang, Re‐Wen Wu, Yushan Chen, Jih‐Yang Ko, Holger Jahr, Wei‐Shiung Lian
62citations -
The interplay between tauopathy and aging through interruption of UPR/Nrf2/autophagy crosstalk in the Alzheimer’s disease transgenic experimental models2023 International Journal of Neuroscience article Medicine Alzheimer's disease research and treatments
Javad Amini, Naser Sanchooli, Mohammad-Hossein Milajerdi, Maryam Baeeri, Mohammad Haddadi, Nima Sanadgol
19citations -
The integrated stress response‐related expression of CHOP due to mitochondrial toxicity is a warning sign for DILI liability2024 Liver International article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Matthijs Vlasveld, Giulia Callegaro, Ciaran P. Fisher, Julie A. Eakins, PAUL A. WALKER, Samantha Lok, +6 more
7citations -
Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models2025 Toxicology in Vitro article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Tamara Meijer, Bas ter Braak, Liesanne Wolters, Steven J. Kunnen, Barira Islam, Ilinca Suciu, +8 more
3citations -
Collaborative SAR Modeling and Prospective In Vitro Validation of Oxidative Stress Activation in Human HepG2 Cells2023 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods Open access
Olivier J. M. Béquignon, José Carlos Gómez-Tamayo, Eelke Bart Lenselink, Steven Wink, Steven W. Hiemstra, Chi Chung Lam, +6 more
3citations -
Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts2021 International Journal of Molecular Sciences article Medicine Liver Disease Diagnosis and Treatment Open access
Sreepradha Eswaran, Anshu Babbar, Hannah K. Drescher, Thomas C. A. Hitch, Thomas Clavel, Moritz Muschaweck, +5 more
2citations -
Postbiotics as Next Generation Biotherapeutics Targeting the Gut–Immune–Metabolic Axis: An Integrative Review2026 Pharmaceuticals article Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Asad Abbas, Ralf Weiskirchen, Muhammad Bilal, Muhammad Khurram Afzal, Abdul Malik, Suhail Akhtar, +6 more
1citations -
Systematic comparison of temporal hepatotoxicant-induced gene network responses across 3 liver test systems2026 Toxicological Sciences article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Tamara Y Danilyuk, Marou Schouten, Elsje J Burgers, Barira Islam, Joost B. Beltman, Peter Bouwman, +2 more
0citations -
Sechium edule: Phytochemistry, Biological Activities, Potential Health Effects, Food-Industry Applications, and Future Perspectives2026 Foods article Biochemistry, Genetics and Molecular Biology Advances in Cucurbitaceae Research Open access
Muhammad Bilal, Asad Abbas, Ralf Weiskirchen, Hammad Hafeez, Andleeb Zahra, Arooj Fatima, +2 more
0citations -
Effects of resveratrol on aortic growth in patients with Marfan syndrome: a single-arm open-label multicentre trial2024 Heart article Biochemistry, Genetics and Molecular Biology Connective tissue disorders research Open access
Daan Bosshardt, Eric Mathew Schrauben, Renske Merton, Roland R L van Kimmenade, Arthur J.H.A. Scholte, Michael G. Dickinson, +7 more
10citations