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Vascular niches are the primary hotspots for aging within the multicellular architecture of cardiac tissue2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cardiac Fibrosis and Remodeling Open access
David Rodríguez Morales, Veronica Larcher, Mariano Ruz Jurado, Lukas Stefan Tombor, Lukas Zanders, Julian U. G. Wagner, +5 more
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Local YB-1, Epo, and EpoR concentrations in fractured bones: results from a porcine model of multiple trauma2023 European journal of medical research article Medicine Erythropoietin and Anemia Treatment Open access
Felix Bläsius, Johannes Greven, Weijun Guo, Eftychios Bolierakis, Zhizhen He, Cavan Lübke, +3 more
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Pathway-centric visualization of cell-cell communication in single-cell transcriptomics data2026 npj Systems Biology and Applications article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Sidrah Maryam, Martin Manolov, Rafael Kramann, Sikander Hayat
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Spatial transcriptomics defines the mechanisms of hiPSC-derived stem cell-mediated repair in human articular cartilage2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Osteoarthritis Treatment and Mechanisms Open access
Y.F. Ramos, Sayedeh Sana Sayedipour, Georgina Shaw, Margo Tuerlings, Timo Schomann, H. Eka D. Suchiman, +7 more
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SRSF7 controls RNA splicing programs driving triple-negative breast cancer metastasis2026 Journal of Experimental & Clinical Cancer Research article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Nasi Liu, Jurjun J S van der Velde, Esmee Koedoot, Marcel Smid, Vanja de Weerd, John W.M. Martens, +2 more
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KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Lohr, Rossella Pellegrino, Mihael Vucur, Michael T. Singer, Veronika Buettner, +7 more
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Phylotranscriptomics Reveals the Reticulate Evolutionary History of a Widespread Diatom Species Complex2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protist diversity and phylogeny Open access
Ozan Çiftçi, Andrew James Alverson, Peter M. van Bodegom, Wade R. Roberts, Adrienne Mertens, Bart Van de Vijver, +5 more
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Multi‐omic profiling of isogenic ApoE3/3 and ApoE4/4 iPSC‐derived astrocytes uncovers altered lipid metabolism and mitochondrial function of ApoE4 astrocytes2023 Alzheimer s & Dementia article Medicine Alzheimer's disease research and treatments Open access
Sascha Koppes, Femke M. Feringa, Aiko Robert, Iris Daphne Kruijff, Damien Olivier‐Jimenez, Lena Erlebach, +6 more
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Fast model-free standardization and integration of single-cell transcriptomics data2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Yang Xu, Rafael Kramann, Rachel Patton McCord, Sikander Hayat
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161 Single-cell spatial in situ transcriptomics unravels vulvar HSIL composition associated with complete response to therapeutic vaccination2022 Regular and Young Investigator Award Abstracts conference-abstract Medicine Cervical Cancer and HPV Research Open access
Ziena Abdulrahman, Mariette I. van Poelgeest, Marij JP Welters, Sjoerd H. van der Burg
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Microbial Invasion and Immunosuppression Drives Adenoma Progression in Early Colorectal Cancer Development2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gut microbiota and health Open access
Wei Liang, Lisa Falk, Daniele Lucarelli, Philipp Putze, Amira Metwaly, Yiran Zheng, +13 more
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Timing matters: Exon skipping therapy is most effective when initiated early in a mouse model of Duchenne muscular dystrophy2026 Molecular Therapy — Nucleic Acids article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access
Sofia Stenler, Junyu Huang, Tirsa L.E. van Westering, Anna M. L. Coenen-Stass, Yahya E. Jad, Kaarel Krjutškov, +3 more
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EchoGO validation and reproducibility compendium2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Camilo Escobar-Sierra, Felix Langschied, Angelina Miller, Pedro A. Inostroza
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EchoGO validation and reproducibility compendium2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Camilo Escobar-Sierra, Felix Langschied, Angelina Miller, Pedro A. Inostroza
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SAHA increases chaperone expression and reduces Z-alpha-1-antitrypsin polymers in a patient specific iPSC-based liver model for alpha-1-antitrypsin deficiency2026 Stem Cell Research & Therapy article Biochemistry, Genetics and Molecular Biology Endoplasmic Reticulum Stress and Disease Open access
Nina Graffmann, Rabea Hokamp, C. Lorch, Malin Fromme, Wasco Wruck, Pavel Strnad, +1 more
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Image-guided alignment of consecutive multi-modal tissue slides2026 Cell Reports Methods article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Benedetta Manzato, Claudio Novella-Rausell, Gangqi Wang, Nina Ogrinc, Rosalie G. J. Rietjens, Marleen E Jacobs, +3 more
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Seed ripening and quinolizidine alkaloid dynamics in Lupinus mutabilis: from gene activity to metabolites2026 Frontiers in Natural Products article Agricultural and Biological Sciences Botanical Research and Chemistry Open access
Philipp Sowa, Marco Loehrer, Jochem Gätgens, Mansi Singh, Ashley Beers, Anika Wiese‐Klinkenberg, +5 more
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