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Nutrimetric Validation of Solanidine as Dietary‐Derived CYP2D6 Activity Marker In Vivo2023 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Julian Peter Müller, Jens Andreas Sarömba, Patrick Ziegler, Roman Tremmel, Jens Rengelshausen, Elke Schaeffeler, +4 more
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A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Dominik Selzer, +9 more
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Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Fatima Zahra Marok, Jan‐Georg Wojtyniak, Dominik Selzer, Robert Dallmann, Jesse Joachim Swen, Henk‐Jan Guchelaar, +2 more
14citations -
Clinical, Cellular, and Molecular Effects of Corticosteroids on the Response to Intradermal Lipopolysaccharide Administration in Healthy Volunteers2021 Clinical Pharmacology & Therapeutics article Medicine Dermatology and Skin Diseases Open access
Thomas P. Buters, Pieter W. Hameeteman, Iris M. E. Jansen, Floris C. van Hindevoort, Wouter ten Voorde, Hendrika W. Grievink, +8 more
12citations -
Population Pharmacokinetics of Trimethoprim/Sulfamethoxazole: Dosage Optimization for Patients with Renal Insufficiency or Receiving Continuous Renal Replacement Therapy2024 Clinical Pharmacology & Therapeutics article Medicine Antibiotics Pharmacokinetics and Efficacy Open access
Emiel Leegwater, Lauren Baidjoe, Erik B. Wilms, Leo G. Visser, Daan Johannes Touw, Brenda C. M. de Winter, +6 more
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A Clinical Pharmacology and Therapeutics Teacher's Guide to Race‐Based Medicine, Inclusivity, and Diversity2022 Clinical Pharmacology & Therapeutics article Biochemistry, Genetics and Molecular Biology Race, Genetics, and Society Open access
Michiel J. Bakkum, Petra Verdonk, Gwen Thomas, Floor van Rosse, Michael Okorie, Paraskevi Papaioannidou, +10 more
12citations -
The Effect of Ibuprofen Exposure and Patient Characteristics on the Closure of the Patent Ductus Arteriosus in Preterm Infants2022 Clinical Pharmacology & Therapeutics article Medicine Cardiovascular Conditions and Treatments Open access
Aline G. J. Engbers, Swantje Völler, Robert B. Flint, Sebastiaan Camiel Goulooze, Johan de Klerk, Elke H. J. Krekels, +5 more
12citations -
Pharmacogenetic Implementation Studies—Lessons Learned From the PREPARE Study2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Henk‐Jan Guchelaar, Cathelijne H. van der Wouden, Lisanne E. N. Manson, H. Abdullah-Koolmees, Kathrin Blagec, Tanja Blagus, +30 more
11citations -
Implementing Pre‐Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Emma C. Bernsen, Eugène T.P. Verwiel, Maaike van der Lee, Jesse Joachim Swen, Marcel Santoso, Leiah J. Brigitha, +7 more
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Getting the Dosage Right: A Vital Role for Clinical Pharmacology in the Era of Precision Medicine2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Iris K. Minichmayr, Mohamad Shebley, Piet H. van der Graaf, Karthik Venkatakrishnan
11citations -
A Genome‐Wide Association Study of Endoxifen Serum Concentrations and Adjuvant Tamoxifen Efficacy in Early‐Stage Breast Cancer Patients2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Anabel Sanchez‐Spitman, Stefan Böhringer, Vincent Olaf Dezentjé, Hans A. J. Gelderblom, Jesse Joachim Swen, Henk‐Jan Guchelaar
11citations -
Mitigating Drug–Target–Drug Complexes in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Switch C5 Inhibitors2023 Clinical Pharmacology & Therapeutics article Immunology and Microbiology Complement system in diseases Open access
Jun‐ichi Nishimura, Antoine Soubret, Noriko Arase, Simon Buatois, Masaki Hotta, Jean‐Eric Charoin, +23 more
10citations -
Mycophenolic Acid Exposure Determines Antibody Formation Following SARS‐CoV ‐2 Vaccination in Kidney Transplant Recipients: A Nested Cohort Study2023 Clinical Pharmacology & Therapeutics article Medicine SARS-CoV-2 and COVID-19 Research Open access
Soufian Meziyerh, Pim Bouwmans, Teun van Gelder, Danny van der Helm, A. Lianne Messchendorp, Paul J. M. van der Boog, +3 more
10citations -
Real‐World Evidence to Inform Regulatory Decision Making: A Scoping Review2024 Clinical Pharmacology & Therapeutics article Economics, Econometrics and Finance Pharmaceutical Economics and Policy Open access
Marieke S. Jansen, Olaf M. Dekkers, Saskia le Cessie, Lotty Hooft, Helga Gardarsdóttir, Anthonius de Boer, +1 more
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ISABELA Studies: Plasma Exposure and Target Engagement Do Not Explain the Lack of Efficacy of Ziritaxestat in Patients with Idiopathic Pulmonary Fibrosis2023 Clinical Pharmacology & Therapeutics article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access
Garrit Jentsch, Stéphane Delage, Matthew J. Randall, Bernt van den Blink, Yasmina Bauer, Florence Namour
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A Nomogram to Predict Severe Toxicity in DPYD Wild‐Type Patients Treated With Capecitabine‐Based Anticancer Regimens2023 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jonathan Emanuel Knikman, Marta López‐Yurda, Didier Meulendijks, Maarten J. Deenen, Jan H.M. Schellens, Jos H. Beijnen, +2 more
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Genome‐wide Association Study of Methotrexate‐Induced Liver Injury in Rheumatoid Arthritis Patients2023 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Frank Eektimmerman, Jesse Joachim Swen, Alfons A den Broeder, Johanna M W Hazes, Fina Kurreeman, Suzanne M. M. Verstappen, +6 more
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Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population2024 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Sumudu Rangika Samarasinghe, Seung‐been Lee, Manuel Corpas, Segun Fatumo, Henk‐Jan Guchelaar, Shivashankar Hiriyur Nagaraj
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Novel Explanted Human Liver Model to Assess Hepatic Extraction, Biliary Excretion and Transporter Function2023 Clinical Pharmacology & Therapeutics article Medicine Organ Transplantation Techniques and Outcomes Open access
Lianne J. Stevens, Jeroen Dubbeld, Jason B. Doppenberg, Bart van Hoek, Aswin L. Menke, Joanne M. Donkers, +6 more
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Oral Oxycodone‐Induced Respiratory Depression During Normocapnia and Hypercapnia: A Pharmacokinetic‐Pharmacodynamic Modeling Study2023 Clinical Pharmacology & Therapeutics article Medicine Pain Management and Opioid Use Open access
Marieke D. Hellinga, Marijke Hyke Algera, Erik Olofsen, Rutger M. van der Schrier, Elise Y. Sarton, Monique van Velzen, +2 more
8citations