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Revealing charge heterogeneity of stressed trastuzumab at the subunit level2023 Analytical and Bioanalytical Chemistry article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Baubek Spanov, Bas Baartmans, Oladapo Olaleye, Simone Nicolardi, Natalia I. Govorukhina, Manfred Wuhrer, +2 more
3citations -
OC 57.1 Peptidomics Reveals Expected and Unexpected Proteolytic Events in Plasma Upon Activation of the Coagulation Cascade2023 Research and Practice in Thrombosis and Haemostasis article Medicine Blood Coagulation and Thrombosis Mechanisms Open access
Jessica Del Castillo Alferez, Floris P. J. van Alphen, Carmen van der Zwaan, Marleen G. Zuurveld, Kamran Bakhtiari, Arie Johan Hoogendijk, +3 more
0citations -
PredLyP: A computational tool for predicting tissue-specific (phago-)lysosomal post-digestion peptides2025 Computational and Structural Biotechnology Journal article Biochemistry, Genetics and Molecular Biology Machine Learning in Bioinformatics Open access
Mattijn Wagt, Cristina Teodósio, Anniek L. de Jager, Jacques J. M. van Dongen, Marcel J. T. Reinders, Paula Díez, +1 more
0citations -
Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1–associated membranous nephropathy2020 Journal of Clinical Investigation article Medicine Renal Diseases and Glomerulopathies Open access cited by 2 patents
George Haddad, Johan M. Lorenzen, Hong Ma, Noortje de Haan, Harald Seeger, Christelle Zaghrini, +11 more
180citations -
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra2021 BMC Biology article Biochemistry, Genetics and Molecular Biology Wnt/β-catenin signaling in development and cancer Open access
Berenice Ziegler, Irene Yiallouros, Benjamin Trageser, Sumit Kumar, Moritz Mercker, Svenja Kling, +9 more
27citations -
Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes2023 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access cited by 3 patents
Ingo Volker Hartung, Joachim Rudolph, Mary M. Mader, Monique P. C. Mulder, Paul Workman
100citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Miriam Kretschmer, Iryna Ivanova, +15 more
22citations -
Interactions between the Parasite Philasterides dicentrarchi and the Immune System of the Turbot Scophthalmus maximus. A Transcriptomic Analysis2020 Biology article Immunology and Microbiology Aquaculture disease management and microbiota Open access
A. Valle, José Manuel Leiro, Patricia Pereiro, Antonio J. Figueras, Beatriz Novoa, Ron P. Dirks, +1 more
17citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland E. Smith, +13 more
17citations -
The iRhom2/ADAM17 Axis Attenuates Bacterial Uptake by Phagocytes in a Cell Autonomous Manner2020 International Journal of Molecular Sciences article Immunology and Microbiology Phagocytosis and Immune Regulation Open access
Anke Seifert, Justyna Wozniak, Stefan Düsterhöft, Petr Kašpárek, Radislav Sedláček, Stephan Dreschers, +3 more
13citations -
Improved N- and C-Terminal Sequencing of Proteins by Combining Positive and Negative Ion MALDI In-Source Decay Mass Spectrometry2020 Analytical Chemistry article Chemistry Mass Spectrometry Techniques and Applications Open access
Simone Nicolardi, David P. A. Kilgour, Yuri E. M. van der Burgt, Manfred Wuhrer
12citations -
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Yuqing Jia, Merve Oyken, Robbert Q. Kim, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Antonius P. A. Janssen, +4 more
7citations -
Profiling of intact blood proteins by matrix‐assisted laser desorption/ionization mass spectrometry without the need for freezing – Dried serum spots as future clinical tools for patient screening2021 Rapid Communications in Mass Spectrometry article Chemistry Mass Spectrometry Techniques and Applications
Charles A. Okai, Manja Wölter, Manuela Ruß, Cornelia Koy, Brîndușa Alina Petre, Werner H. Rath, +2 more
5citations -
Acute liver injury following acetaminophen administration does not activate atrophic pathways in the mouse diaphragm2021 Scientific Reports article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Christian Simon Bruells, P. Duschner, Gernot Marx, Ghislaine Gayan‐Ramirez, Nadine Frank, Thomas Breuer, +3 more
4citations -
In‐Plate Chemical Synthesis of Isopeptide‐Linked SUMOylated Peptide Fluorescence Polarization Reagents for High‐Throughput Screening of SENP Preferences2022 ChemBioChem article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Yara Huppelschoten, Rishov Mukhopadhyay, Jens Buchardt, Thomas E. Nielsen, Alfred C.O. Vertegaal, Huib Ovaa, +1 more
3citations