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Protein Degradation and Inhibitors Sign in to save
Papers per year
Papers 23
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Expanding Chemical Probe Space: Quality Criteria for Covalent and Degrader Probes2023 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access cited by 3 patents
Ingo Volker Hartung, Joachim Rudolph, Mary M. Mader, Monique P. C. Mulder, Paul Workman
100citations -
Chiral Analogues of PFI-1 as BET Inhibitors and Their Functional Role in Myeloid Malignancies2020 ACS Medicinal Chemistry Letters article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access cited by 2 patents
Bianca Altenburg, Marcus Frings, Jan‐Hendrik Schöbel, Jonas Goßen, Kristina Pannen, Kim Vanderliek, +4 more
44citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Miriam Kretschmer, Iryna Ivanova, +15 more
22citations -
Discovery and Functional Characterization of a Potent, Selective, and Metabolically Stable PROTAC of the Protein Kinases DYRK1A and DYRK1B2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Gerrit Wilms, Kevin Schofield, Shayna Maddern, Christopher Foley, Yeng Shaw, Breland E. Smith, +13 more
17citations -
The 17 th EFMC Short Course on Medicinal Chemistry on Small Molecule Protein Degraders2023 ChemMedChem article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Alessio Ciulli, Suzanne O’Connor, Chun‐wa Chung, Ingo Volker Hartung, Andrea Testa, Danette L. Daniels, +1 more
8citations -
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of ARV-102, a PROTAC LRRK2 degrader, in healthy volunteers2025 Parkinsonism & Related Disorders article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors
Sergey Aksenov, Ana LC Zaninotto, Thomas Storz, Y. Folami, C. Lubeski, Marsha MacDougall, +4 more
8citations -
Development of Inhibitors, Probes, and PROTAC Provides a Complete Toolbox to Study PARK7 in the Living Cell2024 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Yuqing Jia, Merve Oyken, Robbert Q. Kim, Rayman T.N. Tjokrodirijo, Arnoud H. de Ru, Antonius P. A. Janssen, +4 more
7citations -
Inducing Receptor Degradation as a Novel Approach to Target CC Chemokine Receptor 2 (CCR2)2024 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Natalia V. Ortiz Zacarı́as, Sascha Röth, Jeremy D. Broekhuis, Daan van der Es, Kévin Moreau, Laura H. Heitman
5citations -
Leveraging Targeted Protein Degradation for G Protein-Coupled Receptors: The Development of CCR2 Molecular Degraders2025 Journal of Medicinal Chemistry article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Khaled Essa, Natalia V. Ortiz Zacarı́as, Sascha Röth, Bo‐Tao Xin, Sabine de Winter, Cas van der Horst, +10 more
2citations -
Reversing PROTAC-induced ASH2L degradation reactivates proliferation in senescent cells2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Janina Müller, Mirna Barsoum, Philip Bussmann, Mohamed H. Elsafi Mabrouk, Roksaneh Sayadi-Boroujeni, Anna-Maria Vllaho, +6 more
0citations -
Engineering brain-penetrant PROTACs: Bridging molecular design and CNS delivery2026 Advanced Drug Delivery Reviews article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Xinuo Li, Jinran Li, Yuan Sun, Tingting Yao, Sai Liu, Haotian Li, +14 more
0citations -
Harnessing PROTAC technology to combat stress hormone receptor activation2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Kei Matthis, Remo Rudolf, +11 more
0citations -
99 Targeted complement inhibition using engineered bispecific antibodies that bind local antigens and endogenous complement regulators as a novel therapeutic approach2023 Immunobiology article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors
Leendert Adrianus Trouw, Leoni Abendstein, Kyra A. Gelderman, Paul W.H.I. Parren, Thomas Harry Sharp, Fleur S. van de Bovenkamp
0citations -
44 Bi-specific antibodies targeting C1q and a tumor antigen activate the complement system independent of C1q-Fc interactions2023 Immunobiology article Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors
Els van der Meijden, Frank J M Beurskens, Leendert Adrianus Trouw
0citations
Most active Aachen authors
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Zheng Zhou 232 citations overall4 papers
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