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Multiscale relaxation dynamics and diffusion of myelin basic protein in solution studied by quasielastic neutron scattering2021 The Journal of Chemical Physics article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics
Abir N. Hassani, Luman Haris, Markus Appel, Tilo Seydel, Andreas Maximilian Stadler, Gerald Reinhard Kneller
16citations -
Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design2022 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Eerappa Rajakumara, Suman Abhishek, Kulhar Nitin, Dubey Saniya, Priyanka Bajaj, Ulrich Schwaneberg, +1 more
47citations -
PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation2022 Proceedings of the National Academy of Sciences article Immunology and Microbiology Biomarkers in Disease Mechanisms Open access
Dylan P. Noone, Douwe J. Dijkstra, Teun T. van der Klugt, Peter A. van Veelen, Arnoud H. de Ru, Paul J. Hensbergen, +2 more
45citations -
Fi-score: a novel approach to characterise protein topology and aid in drug discovery studies2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Austė Kanapeckaitė, Claudia Beaurivage, MATTHEW J. HANCOCK, Erik Verschueren
2citations -
Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein19citations
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Transition between protein-like and polymer-like dynamic behavior: Internal friction in unfolded apomyoglobin depends on denaturing conditions2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
Livia Balacescu, Tobias E. Schrader, Aurel Rădulescu, Piotr A. Zolnierczuk, Olaf Holderer, Stefano Pasini, +2 more
14citations -
Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Biomarkers in Disease Mechanisms Open access cited by 2 patents
Dylan P. Noone, Marjolein M. E. Isendoorn, Sebastiaan M. W. R. Hamers, Mariska E. Keizer, Jip Wulffelé, Tijn T. van der Velden, +4 more
3citations -
Data and Computational Outputs Supporting Structural Filtering Identifies Candidate Rheostat Positions Across Protein Systems2026 Zenodo (CERN European Organization for Nuclear Research) dataset Biochemistry, Genetics and Molecular Biology Protein Structure and Dynamics Open access
J Chander, Alexander Julian, S Lee, Andrew Howard, Rosan C.M. Kuin
0citations -
Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions2022 Proceedings of the National Academy of Sciences article Medicine Influenza Virus Research Studies Open access cited by 9 patents
Fin Milder, Mandy A. C. Jongeneelen, Tina Ritschel, Pascale Bouchier, Ilona J. M. Bisschop, Martijn de Man, +7 more
61citations -
Effects of different ultrasound frequencies on the structure, rheological and functional properties of myosin: Significance of quorum sensing2020 Ultrasonics Sonochemistry article Agricultural and Biological Sciences Meat and Animal Product Quality Open access
Jiahui Chen, Xing Zhang, Chen Yan, Xue Zhao, Anthony Pius Bassey, Xinglian Xu
59citations -
Pan-cancer in silico analysis of somatic mutations in G-protein coupled receptors: The effect of evolutionary conservation and natural variance2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer Genomics and Diagnostics Open access
Brandon J. Bongers, Marina Gorostiola González, X. Wang, Herman van Vlijmen, Willem Jespers, Hugo Gutiérrez‐de‐Terán, +4 more
3citations -
In vitro and in vivo immunogenicity assessment of protein aggregate characteristics2022 International Journal of Pharmaceutics article Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Camilla Thorlaksen, Heidi Schiøler Schultz, Simon K. Gammelgaard, Wim Jiskoot, Nikos S. Hatzakis, Flemming Seier Nielsen, +4 more
27citations -
In vitro and in vivo immunogenicity assessment of protein aggregate characteristics2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein purification and stability Open access
Camilla Thorlaksen, Heidi Schiøler Schultz, Simon K. Gammelgaard, Wim Jiskoot, Nikos S. Hatzakis, Flemming Seier Nielsen, +4 more
0citations -
A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Computer Science Computational Drug Discovery Methods Open access
Jonas Goßen, Simone Albani, Anton Hanke, Benjamin Philipp Joseph, Cathrine C. Bergh, Maria Kuzikov, +14 more
5citations -
Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers2020 Cell Reports article Medicine Viral Infections and Outbreaks Research Open access cited by 15 patents
Lucy Rutten, Morgan S. A. Gilman, Sven Blokland, Jarek Juraszek, Jason S. McLellan, Johannes P. M. Langedijk
80citations