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Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis2023 EMBO Molecular Medicine article Medicine Endometrial and Cervical Cancer Treatments Open access
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, C. Moore, Hayley L. Belnoue-Davis, Susanne Flach, +6 more
5citations -
Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice2023 Science Advances article Biochemistry, Genetics and Molecular Biology Genetics and Neurodevelopmental Disorders Open access
Sarah E. Sheppard, Laura M. Bryant, Rochelle N. Wickramasekara, Courtney Vaccaro, Brynn Robertson, Jodi Hallgren, +93 more
17citations -
SCON—a Short Conditional intrON for conditional knockout with one-step zygote injection2022 Experimental & Molecular Medicine article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Szu-Hsien Sam Wu, Heetak Lee, Réka Szép-Bakonyi, Gabriele Colozza, Ayse Boese, Krista R. Gert, +10 more
8citations -
Pilot study: transduction of primary paraganglioma chromaffin tumour cells with inducible c-MYC drives cell proliferation2026 Experimental and Clinical Endocrinology & Diabetes article Medicine Adrenal and Paraganglionic Tumors Open access
Juan Zhang, Heggert G Rebel, Dominique Duesman, Charlotte J. Dommering, Abbey Schepers, Peter Devilee, +1 more
0citations -
A novel genetic strategy to interrogate an unknown phenotypic modifier: Sdhc KO-Robertsonian mice develop frequent thyroid abnormalities with papillary thyroid carcinoma-like features0citations
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Deciphering the signaling network of breast cancer improves drug sensitivity prediction2021 Cell Systems article Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Marco Tognetti, Attila Gábor, Mi Yang, Valentina Cappelletti, Jonas Windhager, Oscar M. Rueda, +9 more
45citations -
Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody2022 International Journal of Molecular Sciences article Immunology and Microbiology T-cell and B-cell Immunology Open access
Marit J van Elsas, Johan M. S. van der Schoot, Alexander Bartels, Kas Steuten, Duco van Dalen, Zacharias Wijfjes, +5 more
5citations -
A hepatocellular carcinoma model with and without parenchymal liver damage that integrates technical and pathophysiological advantages for therapy testing2024 Pharmacological Research article Medicine Hepatocellular Carcinoma Treatment and Prognosis Open access
Karina Benderski, Paul M. Schneider, Panayiotis Kordeves, Michael Fichter, Jenny Schunke, Federica De Lorenzi, +11 more
4citations -
A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma2021 European Journal of Cancer article Medicine Bladder and Urothelial Cancer Treatments Open access cited by 4 patents
Victor M. Baart, Geertje van der Horst, Marion M. Deken, Shadhvi S. Bhairosingh, Timo Schomann, Vincent Q. Sier, +10 more
16citations -
Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants2025 GeroScience article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Maarouf Baghdadi, Helena M. Hinterding, Thies Gehrmann, Pasquale C. Putter, Mara Neuerburg, Nico Lakenberg, +4 more
2citations -
Functional characterisation of rare variants in genes encoding the MAPK/ERK signalling pathway identified in long-lived Leiden Longevity Study participants2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Helena M. Hinterding, Maarouf Baghdadi, Thies Gehrmann, Pasquale C. Putter, Mara Neuerburg, Nico Lakenberg, +4 more
0citations -
Additional file 1 of Epigenetic priming of mammalian embryonic enhancer elements coordinates developmental gene networks2025 Figshare article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access
Christopher D Todd, Jannat Ijaz, Fereshteh Torabi, Oleksandr Dovgusha, Olivia Cracknell, Tim Lohoff, +10 more
0citations -
Rare genetic variants in the IIS/mTOR signalling pathway identified in exceptionally long-lived individuals show shared in vitro effects associated with lifespan across species2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access
Mara Neuerburg, Larissa Smulders, Erik B. van den Akker, Daniel Kolbe, Filippo Artoni, Isabell Brusius, +10 more
0citations -
The interplay of DNA repair context with target sequence predictably biases Cas9-generated mutations2024 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Ananth Pallaseni, Elin Madli Peets, Gareth Girling, Ivan Kuzmin, Marilin Moor, Núria Muñoz-Subirana, +7 more
18citations -
Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease2022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Genetic and Kidney Cyst Diseases Open access
Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman David Bülow, Tiffany Migeon, Sandrine Placier, +3 more
9citations -
Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family2025 Nature Communications article Medicine Clostridium difficile and Clostridium perfringens research Open access
Elma Mons, Jannie G. E. Henderickx, Ingrid M. J. G. Sanders, Anusca G. Rader, Caroline E. Perkins, Florence M. Stel, +4 more
3citations