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Overexpression of the miR-17-92 cluster in colorectal adenoma organoids causes a carcinoma-like gene expression signature2022 Neoplasia article Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanne R. Martens‐de Kemp, Malgorzata A. Komor, Rosa Hegi, Anne S. Bolijn, Marianne Tijssen, Florence L. M. de Groen, +5 more
15citations -
An integrated automated pipeline for cloning, transient expression, and purification augmenting the plant cell pack platform for biopharmaceutical screening2026 New Biotechnology article Biochemistry, Genetics and Molecular Biology Transgenic Plants and Applications Open access
Monique Schulze, Patrick Opdensteinen, Sándor Albert, Niklas Gabriel, Csaba Matyas Demeter, Johannes F. Buyel, +1 more
0citations -
Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb12021 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology Retinal Development and Disorders Open access
Nanda Boon, C. Henrique Alves, Aat A. Mulder, Charlotte A. Andriessen, Thilo M. Buck, Peter M. J. Quinn, +4 more
14citations -
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells2020 Journal of Cellular and Molecular Medicine article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Tanzeela Awan, Aaron Babendreyer, Abid Mahmood Alvi, Stefan Düsterhöft, Daniela Lambertz, Jörg Walter Bartsch, +2 more
37citations -
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner2024 Journal of Innate Immunity article Immunology and Microbiology Immune Response and Inflammation Open access
Mareike D. Maler, Sophie Zwick, Carsten Kallfass, Peggy Engelhard, Hexin Shi, Laura Hellig, +14 more
2citations -
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy2023 Nature Communications article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 5 patents
Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Stefan Bernhard Thalhammer, David Manuel Mittas, Nina Karguth, Dina Yehia Otify, +15 more
83citations -
Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components2020 Gene Therapy article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Ignazio Maggio, Hidde A. Zittersteijn, Qian Wang, Jin Liu, Josephine M. Janssen, Ivan Toral Ojeda, +4 more
66citations -
Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutations2023 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 1 patent
Maria Carmina Castiello, Martina Di Verniere, Elena Fontana, Sara Penna, Lucia Piceni Sereni, Alessandra Zecchillo, +12 more
4citations -
Donor insertion into CX3CR1 allows epigenetic modulation of a constitutive promoter on hematopoietic stem cells and its activation upon myeloid differentiation2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Iris Ramos-Hernández, Carla Fuster‐García, Araceli Aguilar-González, María L Lozano-Vinagre, Guillermo Guenechea-Amurrio, Francisco Jose Sanchez-Luque, +5 more
3citations -
Functional Intercellular Transmission of miHTT via Extracellular Vesicles: An In Vitro Proof-of-Mechanism Study2022 Cells article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
Roberto D.V.S. Morais, Marina Sogorb-González, Citlali Bar, Nikki C Timmer, M. Leontien van der Bent, Morgane Wartel, +1 more
10citations -
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Tumour-educated platelets for breast cancer detection: biological and technical insights2023 British Journal of Cancer article Biochemistry, Genetics and Molecular Biology Gene expression and cancer classification Open access
Marte C. Liefaard, Kat S Moore, Lennart Mulder, Daan van den Broek, Jelle Wesseling, Gabe S. Sonke, +3 more
27citations -
Truncated FOS impairs osteogenic differentiation and induces prostaglandin and NFκB signalling in an in vitro cell‐of‐origin model for osteoid osteoma and osteoblastoma
Suk Wai Lam, Tatiana Belova, Natasja Franceschini, Brendy E. van den Akker, David G.P. van IJzendoorn, Harald M. M. Mikkers, +5 more
3citations -
Genome-enabled insights into the biology of thrips as crop pests2020 BMC Biology article Biochemistry, Genetics and Molecular Biology Insect Resistance and Genetics Open access
Dorith Rotenberg, Aaron A. Baumann, Sulley K. Ben-Mahmoud, Olivier Christiaens, Wannes Dermauw, Panagiotis Ioannidis, +51 more
106citations