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Structural analyses and substrate profiling of PPEP-3 provide new insights into the molecular basis of Pro-Pro endopeptidase specificity2025 iScience article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Bart Claushuis, Fabian Wojtalla, Lisa Papenhagen, Robert A. Cordfunke, Arnoud H. de Ru, Hans C. van Leeuwen, +3 more
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A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the β-lactamase BlaC7citations
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Corrigendum to “A low-barrier proton shared between two aspartates acts as a conformational switch that changes the substrate specificity of the β-lactamase BlaC” [Int. J. Biol. Macromol. 278 (2024) 134665]0citations
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Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Inger Johansson, Emmanouella M. Xanthopoulou, Yitian Zhou, Anabel Sanchez‐Spitman, Maaike van der Lee, Birgit Malene Wollmann, +6 more
8citations -
Complementary chemical probes and substrates reveal split subsite specificity in a fungal GH12 glucanase2026 ChemRxiv preprint Agricultural and Biological Sciences Polysaccharides and Plant Cell Walls Open access
Thamy L R Corrêa, Nicholas G. S. McGregor, Casper de Boer, Sybrin P. Schröder, Quentin P. O. Foucart, Lianne I. Willems, +4 more
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Structural Basis of Substrate Selectivity and Catalysis in the Mycobacterial Long-Chain Acyl-CoA Carboxylase2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Lipid metabolism and biosynthesis Open access
Ajit Yadav, Nicole Rizzetto, Bogdan I. Florea, Sebastian Geibel
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Exceptional Substrate Diversity in Oxygenation Reactions Catalyzed by a Bis(μ‐oxo) Copper Complex2020 Chemistry - A European Journal article Chemistry Metal-Catalyzed Oxygenation Mechanisms Open access
Melanie Paul, Melissa Teubner, Benjamin Grimm‐Lebsanft, Christiane Golchert, Yannick Meiners, Laura Senft, +13 more
31citations -
Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes2026 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology DNA and Nucleic Acid Chemistry
Li Liu, Yang Lu, Zongxing Yu, Li Tang, Y N Wu, Jim Voorneveld, +4 more
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Protease Specificity Profiling Using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry2025 Methods in molecular biology book-chapter Biochemistry, Genetics and Molecular Biology Chemical Synthesis and Analysis
Bart Claushuis, Robert A. Cordfunke, Arnoud H. de Ru, Peter A. van Veelen, Jeroen Corver, Jan Wouter Drijfhout, +1 more
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Structure and Cooperativity in Substrate–Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design2022 ACS Chemical Biology article Biochemistry, Genetics and Molecular Biology Enzyme Catalysis and Immobilization
Eerappa Rajakumara, Suman Abhishek, Kulhar Nitin, Dubey Saniya, Priyanka Bajaj, Ulrich Schwaneberg, +1 more
47citations -
Non‐prime‐ and prime‐side profiling of P ro‐ P ro endopeptidase specificity using synthetic combinatorial peptide libraries and mass spectrometry2024 FEBS Journal article Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization Open access
Bart Claushuis, Robert A. Cordfunke, Arnoud H. de Ru, Jordy van Angeren, Ulrich Baumann, Peter A. van Veelen, +4 more
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Non-prime- and Prime-side Profiling of Pro-Pro Endopeptidase Specificity Using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Enzyme Production and Characterization Open access
Bart Claushuis, Robert A. Cordfunke, Arnoud H. de Ru, Jordy van Angeren, Ulrich Baumann, Peter A. van Veelen, +4 more
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Assessing substrate quality and contamination of thin film coatings for x-ray optics2024 Space Telescopes and Instrumentation: Ultraviolet to Gamma Ray conference-paper Materials Science Optical Coatings and Gratings
Diego Paredes-Sanz, Sonny Massahi, Sara Svendsen, Desirée Della Monica Ferreira, Ricardo Martins, Nis C. Gellert, +6 more
2citations -
Revealing cell-substrate adhesion at subcellular resolution with ultra-flat field-effect transistor arrays2025 Biosensors and Bioelectronics article Engineering Microfluidic and Bio-sensing Technologies Open access
Ziyu Gao, Susanne Schäfer, Regina Stockmann, Bernd Hoffmann, Rudolf Merkel, Andreas Offenhäusser, +1 more
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Proteome-wide ubiquitinome profiling reveals substrate-specific dynamics within the USP7 network2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Joyce Wolf van der Meer, Jan A. VAN DER KNAAP, Ayestha Sijm, Karel Bezstarosti, Dick H. W. Dekkers, Wouter A. S. Doff, +2 more
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Effect of substrate temperature on in-situ precipitation during laser powder bed fusion of Fe-TiB 2 high modulus steel2023 Virtual and Physical Prototyping article Engineering Additive Manufacturing Materials and Processes Open access
Shahid Hussain, Nicklas Tönnißen, Erika Soares Barreto, Eric Gärtner, Aleksander Kostka, Hauke Springer, +2 more
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Protein degrons and degradation: Exploring substrate recognition and pathway selection in plants2024 The Plant Cell article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Erika Isono, Jianming Li, Pablo Pulido, Wei Siao, Steven H. Spoel, Zhishuo Wang, +2 more
26citations