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Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence2022 Journal of Medicinal Chemistry article Medicine Clostridium difficile and Clostridium perfringens research Open access
Jujun Zhou, John R. Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Taraneh Hajian, +10 more
7citations -
Alterations in DNA methylation associate with reduced migraine and headache days after medication withdrawal treatment in chronic migraine patients: a longitudinal study
Divya Mehta, Irene de Boer, Heidi G. E. Sutherland, Judith A. Pijpers, Charlene Bron, Charlotte K. Bainomugisa, +5 more
22citations -
Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities2026 Angewandte Chemie International Edition article Medicine Microbial Natural Products and Biosynthesis Open access
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa V. Ponomareva, Isaline Fagon, Leslie Fève, +10 more
0citations -
Optimization of 2,3-dihydrophthalazine-1,4-dione PARP inhibitor scaffold for nanomolar potency and specificity towards human PARP102025 European Journal of Medicinal Chemistry article Medicine PARP inhibition in cancer therapy Open access
Juho Alaviuhkola, Maria Giulia Nizi, Chiara Vagaggini, Chiara Sarnari, Barbara E. Lippok, Mirko M. Maksimainen, +8 more
1citations -
A biophysical study of the interactions of palladium( ii ), platinum( ii ) and gold( iii ) complexes of aminopyridyl-2,2′-bipyridine ligands with RNAs and other nucleic acid structures
Francesca Binacchi, Cassandra Elia, Damiano Cirri, Corjan van de Griend, Xue‐Quan Zhou, Luigi Messori, +3 more
5citations -
Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Glioma Diagnosis and Treatment Open access
Hannah Voß, Shweta Godbole, Simon Schlumbohm, Yannis Schumann, Martin Mynarek, Stefan Rutkowski, +14 more
1citations