Clinical Epigenetics

• Trans-acting genetic variants causing multilocus imprinting disturbance (MLID): common mechanisms and consequences

  2022 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Thomas Eggermann, Elzem Yapici, Jet Bliek, Arrate Pereda, Matthias Begemann, Silvia Russo, +13 more

  61

  citations
• Physical activity specifically evokes release of cell-free DNA from granulocytes thereby affecting liquid biopsy

  2022 Clinical Epigenetics article Medicine Lymphoma Diagnosis and Treatment Open access cited by 3 patents

  Elmo W. I. Neuberger, Stephanie Sontag, Alexandra Brahmer, Keito F A Philippi, Markus Philipp Radsak, Wolfgang Wagner, +1 more

  36

  citations
• First step towards a consensus strategy for multi-locus diagnostic testing of imprinting disorders

  2022 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Deborah Mackay, Jet Bliek, Masayo Kagami, Jair Antonio Tenorio, Arrate Pereda, Frédéric Brioude, +23 more

  36

  citations
• PRDM8 reveals aberrant DNA methylation in aging syndromes and is relevant for hematopoietic and neuronal differentiation

  2020 Clinical Epigenetics article Medicine Telomeres, Telomerase, and Senescence Open access cited by 2 patents

  Olivia Cypris, Monika Eipel, Julia Franzen, Corinna Rösseler, Vithurithra Tharmapalan, Chao‐Chung Kuo, +8 more

  31

  citations
• Multi-locus imprinting disturbance (MLID): interim joint statement for clinical and molecular diagnosis

  2024 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Deborah Mackay, Gabriella E. Gazdagh, David Monk, Frédéric Brioude, Éloïse Giabicani, Izabela M. Krzyzewska, +26 more

  24

  citations
• Novel mutation points to a hot spot in CDKN1C causing Silver–Russell syndrome

  2020 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Gerhard Binder, Julian Ziegler, Roland Schweizer, Wisam Habhab, Tobias B. Haack, T. Heinrich, +1 more

  21

  citations
• Frequency of KCNQ1 variants causing loss of methylation of Imprinting Centre 2 in Beckwith-Wiedemann syndrome

  2020 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Carla Eßinger, Stephanie Karch, Ute Moog, György Fekete, Anna Lengyel, Éva Pinti, +2 more

  17

  citations
• Molecular characterisation of 36 multilocus imprinting disturbance (MLID) patients: a comprehensive approach

  2023 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Larissa Bilo, Eguzkine Ochoa, Sunwoo Liv Lee, Daniela Dey, Ingo Kurth, Florian Kraft, +10 more

  15

  citations
• The applications of DNA methylation as a biomarker in kidney transplantation: a systematic review

  2022 Clinical Epigenetics review Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  Iacopo Cristoferi, Tommaso Antonio Giacon, Karin Boer, Myrthe van Baardwijk, Flavia Neri, Manuela Campisi, +5 more

  15

  citations
• Unusual deletion of the maternal 11p15 allele in Beckwith–Wiedemann syndrome with an impact on both imprinting domains

  2021 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Thomas Eggermann, Matthias Begemann, Lutz Pfeiffer

  10

  citations
• Cancer-associated fibroblasts reveal aberrant DNA methylation across different types of cancer

  2024 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  Marco F. Schmidt, Tiago Maié, Thorsten Cramer, Ivan G. Costa, Wolfgang Wagner

  9

  citations
• Maternal uniparental disomy of chromosome 7: how chromosome 7-encoded imprinted genes contribute to the Silver–Russell phenotype

  2025 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Matthias Begemann, Anna Lengyel, Éva Pinti, Árpád Ferenc Kovács, György Fekete, Svea Stratmann, +4 more

  5

  citations
• DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

  2021 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Breast Cancer Treatment Studies Open access

  Philipp Sebastian Jurmeister, Karsten Ernst Weber, Sonia Lorena Villegas, Thomas Karn, Michael Untch, Anne Thieme, +14 more

  5

  citations
• Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

  2023 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access cited by 2 patents

  Ledio Bocova, Wouter H. G. Hubens, Cordula Engel, Steffen Koschmieder, Edgar Jost, Wolfgang Wagner

  4

  citations
• DNA methylation in primary myelofibrosis is partly associated with driver mutations and distinct from other myeloid malignancies

  2025 Clinical Epigenetics article Medicine Myeloproliferative Neoplasms: Diagnosis and Treatment Open access

  Esra Dursun Torlak, Vithurithra Tharmapalan, Kim Kricheldorf, Joelle Schifflers, Madeline J. Caduc, Martin Zenke, +1 more

  3

  citations
• Hypomethylation of the MEG8:Int2-DMR in patients with pathogenic PLAG1 variants suggests new role of the chr14q32 imprinting cluster in Silver-Russell syndrome

  2025 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Genetic Syndromes and Imprinting Open access

  Emilia D’Angelo, Laura Pignata, Francesco Cecere, Alessandro Vimercati, Maria Vittoria Cubellis, Abu Saadat, +9 more

  2

  citations
• Correction: Quantification of hematopoietic stem and progenitor cells by targeted DNA methylation analysis

  2023 Clinical Epigenetics erratum Immunology and Microbiology Immune responses and vaccinations Open access

  Ledio Bocova, Wouter H. G. Hubens, Cordula Engel, Steffen Koschmieder, Edgar Jost, Wolfgang Wagner

  0

  citations
• NSD1 governs H3K36me2-mediated DNA methylation and drives endo-mesodermal differentiation of human iPSCs

  2026 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  Anna Hansknecht, Martina Mankarious, Monica Varona Baranda, Esra Dursun Torlak, Wolfgang Wagner, Kira Zeevaert, +1 more

  0

  citations
• NSD1 governs H3K36me2-mediated DNA methylation and drives endo-mesodermal differentiation of human iPSCs

  2026 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  Anna Hansknecht, Martina Mankarious, Monica Varona Baranda, Esra Dursun Torlak, Wolfgang Wagner, Kira Zeevaert, +1 more

  0

  citations
• Exploring a targeted epigenetic clock based on mortality-associated CpGs as a potential biomarker for frailty

  2026 Clinical Epigenetics article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  Jonathan Awuah, Dhayana Dallmeier, Felix Boehm, Laura Herdtle, Dietrich Rothenbacher, Juan-Felipe Perez-Correa, +1 more

  0

  citations

20 results