Predictable and precise template-free CRISPR editing of pathogenic variants

• A mutational scar-based genome-wide map of DNA double-strand break repair

  2026 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  2

  citations
• MUSICiAn: genome-wide identification of genes involved in DNA repair via control-free mutational spectra analysis

  2026 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  3

  citations
• Signatures in CRISPR Mutational Spectra Reveal Role and Interplay of Genes in DNA Repair

  2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  0

  citations
• Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer

  2025 The Breast article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access

  2

  citations
• Mutated DNMT3A creates a public HLADQ- binding neoantigen on acute myeloid leukemia

  2025 Frontiers in Immunology article Immunology and Microbiology Immunotherapy and Immune Responses Open access

  3

  citations
• MUSICiAn: Genome-wide Identification of Genes Involved in DNA Repair via Control-Free Mutational Spectra Analysis

  2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  3

  citations
• Analyzing the functional effects of DNA variants with gene editing

  2024 Cell Reports Methods article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 2 patents

  13

  citations
• Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 1 patent

  69

  citations
• CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies

  2022 WIREs Mechanisms of Disease article Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access cited by 1 patent

  23

  citations
• SIQ: easy quantitative measurement of mutation profiles in sequencing data

  2022 NAR Genomics and Bioinformatics article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access

  32

  citations
• Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks

  2022 Frontiers in Genetics article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  15

  citations
• Multi-Pathway DNA Double-Strand Break Repair Reporters Reveal Extensive Cross-Talk Between End-Joining, Single Strand Annealing, and Homologous Recombination

  2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  1

  citations
• Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR-Based Functional Screening of Osteoporosis Candidate Genes

  2020 Journal of Bone and Mineral Research article Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access

  44

  citations
• Comprehensive Mapping of Key Regulatory Networks that Drive Oncogene Expression

  2020 Cell Reports article Biochemistry, Genetics and Molecular Biology Genomics and Chromatin Dynamics Open access

  18

  citations
• A genome-wide CRISPR/Cas phenotypic screen for modulators of DUX4 cytotoxicity reveals screen complications

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Muscle Physiology and Disorders Open access

  2

  citations
• Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny

  2020 Cells article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access

  34

  citations

16 results