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Complement system in diseases Sign in to save
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Papers 197
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COMPOSER Part 4: An Optimized Dosing Strategy for Crovalimab in the Treatment of Complement Inhibitor-Naïve or -Experienced Patients with Paroxysmal Nocturnal Hemoglobinuria
Régis Peffault de Latour, Simona Sica, Julia G. Ramos, Jules Hernández‐Sánchez, Jin Seok Kim, Anna Kiialainen, +11 more
3citations -
P774: SUBSTANTIAL INCREASES IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE WITH ORAL IPTACOPAN MONOTHERAPY CONFIRMS CONTROL OF HEMOLYSIS IN COMPLEMENT INHIBITOR-NAÏVE PNH PATIENTS
Régis Peffault de Latour, Bing Han, Jaroslaw Pawel Maciejewski, Yutaka Ueda, Rong Fu, Li Zhang, +15 more
3citations -
RESULTS OF THE PEGASUS PHASE 3 RANDOMIZED TRIAL DEMONSTRATING SUPERIORITY OF THE C3 INHIBITOR PEGCETACOPLAN COMPARED TO ECULIZUMAB IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA2020 Hematology Transfusion and Cell Therapy article Immunology and Microbiology Complement system in diseases Open access
Peter Hillmen, Jeff Szer, Britta Höchsmann, Jens Panse, Jean‐Jacques Kiladjian, Carlos M. DeCastro, +7 more
3citations -
S182: ORAL IPTACOPAN MONOTHERAPY INCREASES PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE VIA CONTROL OF INTRA- AND EXTRAVASCULAR HEMOLYSIS IN ANTI-C5-TREATED PNH PATIENTS WITH ANEMIA
Antonio Maria Risitano, Alexander Röth, Austin Gladston Kulasekararaj, Phillip Scheinberg, Yutaka Ueda, Eros Di Bona, +28 more
2citations -
MDS-273 Oral Iptacopan Monotherapy Increases Paroxysmal Nocturnal Hemoglobinuria (PNH) Red Blood Cell Clone Size Via Control of Intra- and Extravascular Hemolysis in Anti-C5-Treated PNH Patients With Anemia2023 Clinical Lymphoma Myeloma & Leukemia conference-abstract Immunology and Microbiology Complement system in diseases Open access
Antonio Maria Risitano, Alexander Röth, Austin Gladston Kulasekararaj, Phillip Scheinberg, Eros Di Bona, Morag Griffin, +27 more
2citations -
Danicopan As Add-on Therapy to Ravulizumab or Eculizumab in Patients with Paroxysmal Nocturnal Hemoglobinuria: Long-Term Patient-Reported Outcomes from the Phase 3 ALPHA Trial2024 Blood conference-abstract Immunology and Microbiology Complement system in diseases Open access
Caroline Irene Piatek, Jong Wook Lee, Morag Griffin, J Nishimura, Christopher Jordan Patriquin, Hubert Schrezenmeier, +9 more
2citations -
Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system2024 RSC Chemical Biology article Immunology and Microbiology Complement system in diseases Open access
Sebastiaan M. W. R. Hamers, Leoni Abendstein, Aimee L. Boyle, Seino A. K. Jongkees, Thomas Harry Sharp
2citations -
Oral Iptacopan Monotherapy Leads to Long-Term Improvements in Patient (Pt)-Reported Health-Related Quality of Life (HRQoL) and Investigator-Assessed Signs and Symptoms of Paroxysmal Nocturnal Hemoglobinuria (PNH): 48-Week (Wk) Results from the Phase III APPLY-PNH and APPOINT-PNH Trials
Antonio Maria Risitano, Bing Han, Austin Gladston Kulasekararaj, Yasutaka Ueda, Phillip Scheinberg, Jaroslaw Pawel Maciejewski, +7 more
2citations -
Patient-reported outcomes in patients with paroxysmal nocturnal hemoglobinuria treated with crovalimab and approved C5 inhibitors in the phase III COMMODORE 2 and 1 studies2025 Annals of Hematology article Immunology and Microbiology Complement system in diseases Open access
Jens Panse, Bing Han, Jaroslav Čermák, Fernando Ataúlfo González Fernández, Akihiko Gotoh, Austin Gladston Kulasekararaj, +10 more
1citations -
Association of Complement Factor D with Cardiovascular Mortality and Clot Lysis in CKD2025 Journal of the American Society of Nephrology article Immunology and Microbiology Complement system in diseases Open access
Martin Berger, Martin Reugels, Alexandra C.A. Heinzmann, Katharina Lysaja, Marta Rizk, Jaana‐Sophia Kern, +5 more
1citations -
Characteristics and Management of Patients With Immune Thrombotic Thrombocytopenic Purpura Admitted to the Intensive Care Unit: A Multicenter Retrospective Analysis2025 American Journal of Hematology article Immunology and Microbiology Complement system in diseases Open access
Lucas Kühne, Linus Alexander Völker, Ulf Schönermarck, Christian Pfrepper, Asterios Tzalavras, Ralph T. Wendt, +15 more
1citations -
Thrombotisch-thrombozytopenische Purpura – eine differenzialdiagnostische Herausforderung im Notfall2023 Medizinische Klinik - Intensivmedizin und Notfallmedizin article Immunology and Microbiology Complement system in diseases Open access
Fedai Özcan, Martin Köhrmann, Sirak Petros, Andreas Goette, Peter Bramlage, Martin Bommer, +1 more
1citations -
P781: EVALUATION OF PEGCETACOPLAN TREATMENT SUCCESS IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA WITH AND WITHOUT BONE MARROW FAILURE: A MOVE TOWARDS INDIVIDUALIZED PATIENT TREATMENT
Jeff Szer, Jens Panse, Austin Gladston Kulasekararaj, Monika Oliver, Bruno Fattizzo, Jun‐ichi Nishimura, +3 more
1citations
Most active Aachen authors
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Jens Panse 10,288 citations overall71 papers
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Régis Peffault de Latour 20,463 citations overall20 papers
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Leendert Adrianus Trouw 13,728 citations overall20 papers
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Antonio Maria Risitano 16,882 citations overall16 papers
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Mohamed R. Daha 31,961 citations overall10 papers
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Cees van Kooten 25,919 citations overall10 papers
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Austin Gladston Kulasekararaj 11,908 citations overall9 papers
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Flore Sicre de Fontbrune 6,345 citations overall8 papers
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Thomas Harry Sharp 3,049 citations overall8 papers
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Mieke F. van Essen 744 citations overall8 papers
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Anja Mühlfeld 2,409 citations overall7 papers
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Paul W.H.I. Parren 32,989 citations overall6 papers
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Haiyu Wang 1,710 citations overall6 papers
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Douwe J. Dijkstra 371 citations overall6 papers
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Leoni Abendstein 215 citations overall6 papers