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Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system

RSC Chemical Biology, vol. 5, pp. 787–799

Abstract

" - peptide-based activators of complement - and underscores the potential of macrocyclic peptides for complement modulation, offering potential advantages over traditional biologicals in terms of size, production, and administration.

Authors 5

  1. Leiden University · Leiden University Medical Center

    Affiliation as printed

    Department of Cell and Chemical Biology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands

  2. Leiden University · Leiden University Medical Center

    Affiliation as printed

    Department of Cell and Chemical Biology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands

  3. Leiden University · University of Bristol

    Affiliation as printed

    Leiden Institute of Chemistry, Leiden University, 2333 CC Leiden, The Netherlands

    School of Chemistry, University of Bristol, Bristol, BS8 1QU, UK

  4. Seino A. K. Jongkees corresponding

    Vrije Universiteit Amsterdam

    Affiliation as printed

    Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands

  5. Leiden University · Leiden University Medical Center · University of Bristol

    Affiliation as printed

    Department of Cell and Chemical Biology, Leiden University Medical Centre, 2300 RC Leiden, The Netherlands

    School of Biochemistry, University of Bristol, Bristol, BS8 1TD, UK

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References 60