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Complement system in diseases Sign in to save
Papers per year
Papers 197
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Fatigue and health‐related quality of life in paroxysmal nocturnal haemoglobinuria: A post hoc analysis of the pegcetacoplan PEGASUS trial data2023 European Journal Of Haematology article Immunology and Microbiology Complement system in diseases Open access
Jens Panse, Koo Wilson, Jesse Fishman, Piotr Wojciechowski, Marlena Wdowiak, Regina Horneff, +3 more
6citations -
Post-translationally modified proteins bind and activate complement with implications for cellular uptake and autoantibody formation2025 Journal of Autoimmunity article Immunology and Microbiology Complement system in diseases Open access
Michelle D van den Beukel, Lu Zhang, Stef van der Meulen, Nicole V. Borggreven, Sandrine Nugteren, Matthijs C. Brouwer, +8 more
6citations -
Development of an in vitro system and model-based translational framework to assess haemolysis risk following intravenous abuse of medications containing polyethylene oxide2020 Toxicology in Vitro article Immunology and Microbiology Complement system in diseases Open access
Peter Persich, Gerwin Erik Engels, Willem van Oeveren, Eric Galia, Stephan Benay, Susanne Thun
5citations -
S183: PHASE III RANDOMIZED, MULTICENTER, OPEN-LABEL COMMODORE 1 TRIAL: COMPARISON OF CROVALIMAB VS ECULIZUMAB IN COMPLEMENT INHIBITOR-EXPERIENCED PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH)
Phillip Scheinberg, Diego V. Clé, Valentina Giai, Marek Hus, Jin Seok Kim, Cristina Barrenetxea Lekue, +11 more
5citations -
Engineering Agonistic Bispecifics to Investigate the Influence of Distance on Surface-Mediated Complement Activation2024 The Journal of Immunology article Immunology and Microbiology Complement system in diseases Open access
Sebastiaan M. W. R. Hamers, Aimee L. Boyle, Thomas Harry Sharp
5citations -
Structural Insights Into Complement Inhibition: Visualizing Distinct Binding Modes of C4b-Binding Protein Complexes With C4b and SAP2025 Molecular & Cellular Proteomics article Immunology and Microbiology Complement system in diseases Open access
Tereza Kadavá, Jürgen Strasser, Maryam Marefat, Victor C. Yin, Johannes Preiner, Leendert Adrianus Trouw, +1 more
5citations -
Monotherapy Treatment with Zaltenibart (OMS906), an Alternative Pathway Masp-3 Inhibitor, Improved Key Hematologic Parameters in Patients with PNH with a Suboptimal Response to Ravulizumab: Interim Results from a Phase 2 Proof-of-Concept Study
Morag Griffin, Richard J. Kelly, Mathilde Gavillet, Petra Muus, Britta Hoechsmann, W. Jason Cummings, +4 more
4citations -
Efficacy, Safety, and Quality of Life of Pegcetacoplan in Japanese Patients with Paroxysmal Nocturnal Hemoglobinuria Treated within the Phase 3 PEGASUS Trial2024 Acta Haematologica article Immunology and Microbiology Complement system in diseases Open access
Hisakazu Nishimori, Hideyuki Nakazawa, Shinobu Tamura, Toshiki Uchida, Kensuke Usuki, Johan Szamosi, +3 more
4citations -
Moving toward Individual Treatment Goals with Pegcetacoplan in Patients with PNH and Impaired Bone Marrow Function2024 International Journal of Molecular Sciences article Immunology and Microbiology Complement system in diseases Open access
Jeff Szer, Jens Panse, Austin Gladston Kulasekararaj, Monika Oliver, Bruno Fattizzo, J Nishimura, +3 more
4citations -
Patient-Reported Outcomes (PROs) in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Crovalimab and Eculizumab: Results from the Phase III Randomized COMMODORE 2 and COMMODORE 1 Trials
Jens Panse, Jaroslav Čermák, Olena Kyselova, Akihiko Gotoh, Fahri Şahin, Hubert Schrezenmeier, +3 more
4citations -
Characterising Prognostic Complement Biomarkers during Clinical Normothermic Machine Perfusion for Renal Transplantation2025 American Journal of Transplantation article Immunology and Microbiology Complement system in diseases Open access
John T. Fallon, Richard Dumbill, Mieke F. van Essen, Constantin C. Coussios, R J Ploeg, Peter John Friend, +1 more
4citations -
Alternative pathway–mediated tubular complement activation in human proteinuric kidney diseases: a proof-of-concept study2025 Clinical Kidney Journal article Immunology and Microbiology Complement system in diseases Open access
Firas Farisi Alkaff, Rosa G. M. Lammerts, Gesa Tiller, Marius Christianus van den Heuvel, Ingeborg M. Bajema, Mohamed R. Daha, +2 more
4citations -
Improvements in hematologic markers and decreases in fatigue with pegcetacoplan for patients with paroxysmal nocturnal hemoglobinuria and mild or moderate anemia (hemoglobin ≥10 g/dL) who had received eculizumab or were naive to complement inhibitors
Jens Panse, Nicolas Daguindau, Sonia Okuyama, Régis Peffault de Latour, Philippe Schafhausen, Nicole Straetmans, +3 more
3citations -
An Optimized Crovalimab Dose and Regimen Reduced the Formation of Drug-Target-Drug Complexes in Patients with Paroxysmal Nocturnal Hemoglobinuria from the Phase I/II COMPOSER Trial
Jun‐ichi Nishimura, Antoine Soubret, Simon Buatois, Jean‐Eric Charoin, Sasha Sreckovic, Christoph Marcus Bucher, +21 more
3citations
Most active Aachen authors
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Jens Panse 10,288 citations overall71 papers
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Régis Peffault de Latour 20,463 citations overall20 papers
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Leendert Adrianus Trouw 13,728 citations overall20 papers
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Antonio Maria Risitano 16,882 citations overall16 papers
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Mohamed R. Daha 31,961 citations overall10 papers
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Cees van Kooten 25,919 citations overall10 papers
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Austin Gladston Kulasekararaj 11,908 citations overall9 papers
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Flore Sicre de Fontbrune 6,345 citations overall8 papers
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Thomas Harry Sharp 3,049 citations overall8 papers
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Mieke F. van Essen 744 citations overall8 papers
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Anja Mühlfeld 2,409 citations overall7 papers
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Paul W.H.I. Parren 32,989 citations overall6 papers
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Haiyu Wang 1,710 citations overall6 papers
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Douwe J. Dijkstra 371 citations overall6 papers
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Leoni Abendstein 215 citations overall6 papers