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Utilizing rat kidney gene co-expression networks to enhance safety assessment biomarker identification and human translation2025 iScience article Biochemistry, Genetics and Molecular Biology Bioinformatics and Genomic Networks Open access
Steven J. Kunnen, Giulia Callegaro, Jeffrey J. Sutherland, Panuwat Trairatphisan, Hugo W van Kessel, Lukas S. Wijaya, +11 more
7citations -
An adaptive phase II/III safety and efficacy randomized controlled trial of single day or three-day fixed-dose albendazole-ivermectin co-formulation versus albendazole for the treatment of Trichuris trichiura and other STH infections. ALIVE trial protocol2022 Gates Open Research article Immunology and Microbiology Parasites and Host Interactions Open access
Alejandro Javier Krolewiecki, Wendemagegn Enbiale, Javier Gandasegui, Lisette van Lieshout, Stella Kepha, Augusto Messa, +15 more
16citations -
Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study2020 The Lancet HIV article Immunology and Microbiology HIV Research and Treatment Open access cited by 3 patents
Lindsey Robert Baden, Daniel J Stieh, Michal Sarnecki, Stephen R. Walsh, Georgia D. Tomaras, James G. Kublin, +35 more
88citations -
A phase I, randomized, double‐blind, placebo‐controlled, single‐ and multiple dose escalation study evaluating the safety, pharmacokinetics and pharmacodynamics of VX‐128, a highly selective Nav1.8 inhibitor, in healthy adults
Hemme J. Hijma, Emilie M.J. van Brummelen, Pieter S. Siebenga, Geert Jan Groeneveld
19citations -
Mosaic HIV-1 vaccine regimen in southern African women (Imbokodo/HVTN 705/HPX2008): a randomised, double-blind, placebo-controlled, phase 2b trial2024 The Lancet Infectious Diseases article Immunology and Microbiology HIV Research and Treatment Open access
Glenda Gray, Kathryn Therese Mngadi, Ludo Lavreys, Steven Nijs, Peter B. Gilbert, John Hural, +58 more
46citations -
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment2021 Archives of Toxicology article Pharmacology, Toxicology and Pharmaceutics Drug-Induced Hepatotoxicity and Protection Open access
Giulia Callegaro, Steven J. Kunnen, Panuwat Trairatphisan, Solène Grosdidier, Marije Niemeijer, Wouter den Hollander, +9 more
43citations -
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial2020 Journal of Psychopharmacology article Biochemistry, Genetics and Molecular Biology Adenosine and Purinergic Signaling
Kasper Recourt, Jasper van der Aart, Gabriël E. Jacobs, Marieke de Kam, Wayne Curtis Drevets, Luc Van Nueten, +7 more
61citations -
Life cycle assessment-guided cleaner production of amikacin: Sustainability analysis among eight synthesis routes2026 Journal of Cleaner Production article Environmental Science Environmental Impact and Sustainability Open access
Ruixing Li, Justin Z. Lian, Ziyue Han, Lynda Thubelihle Kanye, Yiru Yan, Kaixin Ma, +3 more
0citations -
Discovery and Optimization of Potent and Subtype-Selective Urea-Derived Na V 1.8 Inhibitors2026 ACS Medicinal Chemistry Letters article Biochemistry, Genetics and Molecular Biology Ion channel regulation and function Open access
Clemens Dialer, Sebastian Krüger, Markus Wagener, Marcel Mülbaier, Sebastian Peil, Mauro Marigo, +18 more
1citations
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