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Highly Loaded Reactive Oxygen Species–Responsive Theranostic Lenvatinib‐Prodrug Nanoparticles Produced by Dispersion Polymerization2025 Advanced NanoBiomed Research article Materials Science Nanoparticle-Based Drug Delivery Open access
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Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles2020 Journal of the American Chemical Society article Immunology and Microbiology Immunotherapy and Immune Responses Open access cited by 5 patents
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Highly Loaded Reactive Oxygen Species–Responsive Theranostic Lenvatinib-Prodrug Nanoparticles Produced by Dispersion Polymerization2025 Advanced NanoBiomed Research article Materials Science Nanoparticle-Based Drug Delivery Open access
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Esterase-Sensitive Prodrugs of a Potent Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT) Display Cellular Activity2021 Biomolecules article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
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Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance2020 Chemistry - A European Journal article Biochemistry, Genetics and Molecular Biology Antibiotic Resistance in Bacteria Open access
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Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate2025 Advanced Healthcare Materials article Medicine Photodynamic Therapy Research Studies Open access
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Safety, pharmacokinetics, and pharmacodynamics of Gln‐1062, a prodrug of galantamine2020 Alzheimer s & Dementia Translational Research & Clinical Interventions article Chemistry Chemical synthesis and alkaloids Open access cited by 6 patents
C. J. G. Bakker, Jasper van der Aart, Ellen P. Hart, Erica Surya Klaassen, Kirsten Riber Bergmann, Michiel Joost van Esdonk, +2 more
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Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors2023 Journal of the American Chemical Society article Medicine Metal complexes synthesis and properties Open access
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Synthesis and Evaluation of Benzylic 18F-Labeled N-Biphenylalkynyl Nipecotic Acid Derivatives for PET Imaging of GABA Transporter 12025 ACS Chemical Neuroscience article Medicine Radiopharmaceutical Chemistry and Applications Open access
Niels Knippenberg, Matthias Bauwens, Alexandru Florea, Soma Rudi, Olaf E. M. G. Schijns, Govert Hoogland, +8 more
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Immunoproteasome Inhibitor–Doxorubicin Conjugates Target Multiple Myeloma Cells and Release Doxorubicin upon Low-Dose Photon Irradiation2020 Journal of the American Chemical Society article Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Elmer Maurits, Michel J. van de Graaff, Santina Maiorana, Dennis P. A. Wander, Patrick M. Dekker, Sabina Y. van der Zanden, +4 more
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A phase I first-in-man study to investigate the pharmacokinetics and safety of liposomal dexamethasone in patients with progressive multiple myeloma2023 Drug Delivery and Translational Research article Medicine Multiple Myeloma Research and Treatments Open access
Josbert M. Metselaar, Twan Lammers, Amelie Boquoi, Roland R. Fenk, Fabio J. Testaquadra, Mirle Schemionek, +4 more
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SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species2022 eLife article Pharmacology, Toxicology and Pharmaceutics Bioactive Compounds and Antitumor Agents Open access
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Engineering brain-penetrant PROTACs: Bridging molecular design and CNS delivery2026 Advanced Drug Delivery Reviews review Biochemistry, Genetics and Molecular Biology Protein Degradation and Inhibitors Open access
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