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Estimating the potential impact of implementing pre‐emptive pharmacogenetic testing in primary care across the UK2021 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Essra Youssef, Charlotte L. Kirkdale, David John Wright, Henk‐Jan Guchelaar, Tracey Thornley
46citations -
Pharmacogenetic Panel Testing: A Review of Current Practice and Potential for Clinical Implementation2024 The Annual Review of Pharmacology and Toxicology review Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Romy Mosch, Maaike van der Lee, Henk‐Jan Guchelaar, Jesse Joachim Swen
21citations -
The PREPARE study: benefits of pharmacogenetic testing are unclear – Authors' reply2023 The Lancet letter Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Jesse Joachim Swen, Lisanne E. N. Manson, Stefan Böhringer, Munir Pirmohamed, Henk‐Jan Guchelaar
16citations -
Evaluation of stabilizing additives to protect activities of cytochrome P450 enzymes for in vitro drug testing and pharmacogenetic studies: Focus on CYP2D62025 Biochimica et Biophysica Acta (BBA) - General Subjects article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Sabrina Yamoune, Henner Koch, Daniel Delev, Yvonne G. Weber, Julia Stingl
3citations -
The influence of age, gender and pharmacogenetic profiles on the perspective on medicines in the German EMPAR study2024 PLoS ONE article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Veronica Atemnkeng Ntam, Tatjana Huebner, Michael Steffens, Christoph Roethlein, Britta Haenisch, Julia Stingl, +2 more
1citations -
Pharmacogenetic Implementation Studies—Lessons Learned From the PREPARE Study2025 Clinical Pharmacology & Therapeutics article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Henk‐Jan Guchelaar, Cathelijne H. van der Wouden, Lisanne E. N. Manson, H. Abdullah-Koolmees, Kathrin Blagec, Tanja Blagus, +30 more
10citations -
Clinical Benefits and Utility of Pretherapeutic DPYD and UGT1A1 Testing in Gastrointestinal Cancer2024 JAMA Network Open article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Rossana Roncato, Alessia Bignucolo, Elena Peruzzi, Marcella Montico, Elena De Mattia, Luisa Foltran, +8 more
25citations -
Applying Next-Generation Sequencing Platforms for Pharmacogenomic Testing in Clinical Practice2021 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Alireza Tafazoli, Henk‐Jan Guchelaar, Wojciech Miltyk, Adam Jacek Kretowski, Jesse Joachim Swen
65citations -
Pharmacogenetic CYP2B6 variants affect steroid hormone metabolism in human breast cancer cells2026 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Marco Hoffmann, Julian Peter Müller, Stefan Düsterhöft, Sabrina Yamoune, Katja Susanne Just, Julia Carolin Stingl
0citations -
Implementation of pre‐emptive testing of a pharmacogenomic panel in clinical practice: Where do we stand?2023 British Journal of Clinical Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Elena Peruzzi, Rossana Roncato, Elena De Mattia, Alessia Bignucolo, Jesse Joachim Swen, Henk‐Jan Guchelaar, +2 more
29citations -
Assessing the Implementation of Pharmacogenomic Panel-Testing in Primary Care in the Netherlands Utilizing a Theoretical Framework2020 Journal of Clinical Medicine article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Cathelijne H. van der Wouden, Ellen Paasman, Martina Teichert, Mathilde R. Crone, Henk‐Jan Guchelaar, Jesse Joachim Swen
39citations -
Optimisation of pharmacotherapy in psychiatry through therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests: Focus on antipsychotics2024 The World Journal of Biological Psychiatry article Medicine Schizophrenia research and treatment Open access
Xenia Marlene Hart, Gerhard Gründer, Nicolas Ansermot, Andreas Conca, Emmanuelle Corruble, Séverine Crettol, +28 more
38citations -
Feasibility of Community Pharmacist-Initiated and Point-of-Care CYP2C19 Genotype-Guided De-Escalation of Oral P2Y12 Inhibitors2023 Genes article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Amar D. Levens, Melina C. den Haan, J. Wouter Jukema, Mette Heringa, Wilbert B. van den Hout, Dirk Jan A. R. Moes, +1 more
11citations -
Influence of metabolic profiles on the safety of drug therapy in routine care in Germany: protocol of the cohort study EMPAR2020 BMJ Open article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Tatjana Huebner, Michael Steffens, Roland Linder, Jochen Fracowiak, Daria Langner, Marco Garling, +5 more
2citations -
The Effect of Genotyping on the Number of Pharmacotherapeutic Gene–Drug Interventions in Chronic Kidney Disease Patients2023 Pharmacy article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Marieke Kerskes, Carien J. M. E. van den Eijnde, Albert‐Jan L.H.J. Aarnoudse, Rene J. E. Grouls, Birgit A. L. M. Deiman, Maarten J. Deenen
6citations -
Cost-Effectiveness of Pharmacogenomics-Guided Prescribing to Prevent Gene-Drug-Related Deaths: A Decision-Analytic Model2022 Frontiers in Pharmacology article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism Open access
Cathelijne H. van der Wouden, Heiralde Marck, Henk‐Jan Guchelaar, Jesse Joachim Swen, Wilbert B. van den Hout
31citations -
Pharmacogenomics: A primer for the military mental health provider2020 Journal of Military Veteran and Family Health article Pharmacology, Toxicology and Pharmaceutics Pharmacogenetics and Drug Metabolism
Gary H. Wynn, Rakesh Jetly, Eric H. G. J. M. Vermetten, Shawn G. Rhind, Wayne Willmott
3citations