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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids2020 Cell Systems article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Jeremy J. Velazquez, Ryan LeGraw, Farzaneh Moghadam, Yuqi Tan, Jacquelyn A. Kilbourne, Joseph C. Maggiore, +8 more
110citations -
Rethinking organoid technology through bioengineering2020 Nature Materials article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 2 patents
Elena Garreta, Roger Dale Kamm, Susana M. Chuva de Sousa Lopes, Madeline A. Lancaster, Ron Weiss, Xavier Trepat, +2 more
337citations -
Engineering multicellular living systems—a Keystone Symposia report2022 Annals of the New York Academy of Sciences article Engineering 3D Printing in Biomedical Research Open access
Jennifer Cable, Paola Arlotta, Kevin Kit Parker, Alex J. Hughes, Katharine Goodwin, Christine L. Mummery, +19 more
6citations -
Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Jeremy J. Velazquez, Ryan LeGraw, Farzaneh Moghadam, Yuqi Tan, Jacquelyn A. Kilbourne, Joshua Hislop, +7 more
4citations -
Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss2023 Nature Communications article Medicine Hepatocellular Carcinoma Treatment and Prognosis Open access
Laura Rüland, Francesco Andreatta, Simone Massalini, Susana M. Chuva de Sousa Lopes, Hans C. Clevers, Delilah F. G. Hendriks, +1 more
34citations -
Biomaterials in organoid research: current state and future directions2026 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Hydrogels: synthesis, properties, applications Open access
Laura Klasen, Ramin Nasehi, Lennart Selzener, Laura De Laporte
0citations -
Large-scale engineering of hiPSC-derived nephron sheets and cryopreservation of their progenitors2022 Stem Cell Research & Therapy article Biochemistry, Genetics and Molecular Biology Pluripotent Stem Cells Research Open access cited by 1 patent
Loes E. Wiersma, M. Cristina Avramut, Ellen Lievers, Ton J. Rabelink, Cathelijne W. van den Berg
14citations -
An engineered tumor organoid model reveals cellular identity and signaling trajectories underlying translocation RCC2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Renal cell carcinoma treatment Open access
Maroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung TT Pham, Philip Lijnzaad, Terezinha Maria de Souza, Sepide Derakshan, +10 more
0citations -
Cellulose Nanofibril Hydrogel Promotes Hepatic Differentiation of Human Liver Organoids2020 Advanced Healthcare Materials article Materials Science Advanced Cellulose Research Studies Open access cited by 2 patents
Melanie Krüger, Loes A. Oosterhoff, Monique E. van Wolferen, Simon Schiele, Andreas Walther, Niels Geijsen, +4 more
92citations -
Dynamic suspension culture enhances scalable maturation of hiPSC-derived cartilage organoids for regenerative medicine2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tissue Engineering and Regenerative Medicine Open access
Giorgia Mazzini, Evelyn Houtman, Marcella van Hoolwerff, Merel L. Janssen, Sayedeh Sana Sayedipour, Ghazaleh Hajmousa, +4 more
0citations -
High level of polarized engraftment of porcine intrahepatic cholangiocyte organoids in decellularized liver scaffolds2022 Journal of Cellular and Molecular Medicine article Medicine Tissue Engineering and Regenerative Medicine Open access
Melanie Krüger, Roos‐Anne Samsom, Loes A. Oosterhoff, Monique E. van Wolferen, H.S. Kooistra, Niels Geijsen, +5 more
11citations -
Mini-hearts for disease modeling and drug testing – process optimization versus biological functionality2026 Frontiers in Bioengineering and Biotechnology article Medicine Tissue Engineering and Regenerative Medicine Open access
Jana Hecking, Mariel Cano-Jorge, R. C. Passier, José M. Rivera‐Arbeláez
0citations -
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids2023 Nature Communications article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Maarten H. Geurts, Shashank Gandhi, Matteo Boretto, Ninouk Akkerman, Lucca L. M. Derks, Gijs J. F. van Son, +10 more
65citations -
Editorial: Extracellular matrix-like microenvironments for in vitro models and regenerative medicine2024 Frontiers in Bioengineering and Biotechnology editorial Medicine Tissue Engineering and Regenerative Medicine Open access
Arturo Ibáñez‐Fonseca, Alicia Fernández‐Colino, Bárbara Blanco‐Fernandez, Dorela D. Shuboni‐Mulligan
1citations -
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 15 patents
Benedetta Artegiani, Delilah F. G. Hendriks, Joep Beumer, Rutger N.U. Kok, Xuan Zheng, Indi P. Joore, +4 more
29citations