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Comparing robotic and manual injection methods in zebrafish embryos for high-throughput RNA silencing using CRISPR-RfxCas13d2024 BioTechniques article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Joaquín Abugattas-Núñez del Prado, Yi Ding, Jan de Sonneville, Kees-Jan van der Kolk, Miguel A. Moreno-Mateos, Edward Málaga‐Trillo, +1 more
5citations -
Silencing of the von Willebrand factor gene in proatherothrombotic APOE∗3-Leiden.CETP transgenic mice2025 Research and Practice in Thrombosis and Haemostasis article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Yvonne K. Jongejan, Richard J. Dirven, Elisa Schrader Echeverri, Amanda C. M. Pronk, Sander Kooijman, Patrick C.N. Rensen, +3 more
1citations -
An antisense noncoding RNA enhances translation via localized structural rearrangements of its cognate mRNA2021 The Plant Cell article Biochemistry, Genetics and Molecular Biology RNA Research and Splicing Open access
Rodrigo Siqueira Reis, Jules Deforges, Romy Schmidt, Jos H. M. Schippers, Yves Poirier
33citations -
Are we creating a new phenotype? Physiological barriers and ethical considerations in the treatment of hereditary transthyretin-amyloidosis2021 Neurological Research and Practice article Biochemistry, Genetics and Molecular Biology Amyloidosis: Diagnosis, Treatment, Outcomes Open access
Maike Franziska Dohrn, Jessica Medina, Karmele Olaciregui Dague, Ernst Hund
25citations -
The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival2021 Oncogene article Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research Open access
Shanna Dewaele, Louis Delhaye, Boél De Paepe, Eric James de Bony, Jilke De Wilde, Katrien Vanderheyden, +18 more
30citations -
Enhancing stability of recombinant CHO cells by CRISPR/Cas9-mediated site-specific integration into regions with distinct histone modifications2022 Frontiers in Bioengineering and Biotechnology article Biochemistry, Genetics and Molecular Biology Viral Infectious Diseases and Gene Expression in Insects Open access cited by 4 patents
Oliver Hertel, Anne Neuß, Tobias Busche, David Brandt, Jörn Kalinowski, Janina Bahnemann, +1 more
20citations -
Priming for enhanced ARGONAUTE2 activation accompanies induced resistance to cucumber mosaic virus in Arabidopsis thaliana2020 Molecular Plant Pathology article Agricultural and Biological Sciences Plant-Microbe Interactions and Immunity Open access
Sugihiro Ando, Michal R. Jaskiewicz, Sei Mochizuki, Saeko Koseki, Shuhei Miyashita, Hideki Takahashi, +1 more
39citations -
Efficient Downregulation of Alk4 in Skeletal Muscle After Systemic Treatment with Conjugated siRNAs in a Mouse Model for Duchenne Muscular Dystrophy2022 Nucleic Acid Therapeutics article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access
Sarah Engelbeen, Svetlana Pasteuning-Vuhman, Rubina Giare Parmar, Klaus Charissé, Laura Sepp‐Lorenzino, Muthiah A. Manoharan, +2 more
14citations -
N-6-Methyladenosine in Vasoactive microRNAs during Hypoxia; A Novel Role for METTL42022 International Journal of Molecular Sciences article Biochemistry, Genetics and Molecular Biology RNA modifications and cancer Open access
Daphne A. L. van den Homberg, Reginald V.C.T. van der Kwast, Paul H.A. Quax, Anne Yaël Nossent
40citations -
Opportunities and challenges for antisense oligonucleotide therapies2020 Journal of Inherited Metabolic Disease article Biochemistry, Genetics and Molecular Biology RNA Interference and Gene Delivery Open access cited by 1 patent
Elsa C. Kuijper, Atze J. Bergsma, W.W.M. Pim Pijnappel, Annemieke M Aartsma-Rus
155citations -
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling2021 Cardiovascular Research article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Kim van Kuijk, Jasper A. F. Demandt, Javier Perales-Patón, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, +13 more
40citations -
Human atherosclerotic plaque transcriptomics reveals endothelial beta-2 spectrin as a potential regulator a leaky plaque microvasculature phenotype2024 Angiogenesis article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Timo Rademakers, Marco Manca, Han Young Jin, Tanguy Orban, Ljubica Perisic Matic, Hubertus J. M. Frissen, +16 more
11citations -
Deficiency of myeloid prolyl hydroxylase domain proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signaling2021 European Heart Journal article Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases
Judith C. Sluimer, Kim van Kuijk, Jasper A. F. Demandt, Javier Perales-Patón, Christoph Kuppe, Han Young Jin, +9 more
0citations -
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling2020 Circulation Research article Biochemistry, Genetics and Molecular Biology Protease and Inhibitor Mechanisms Open access
Urszula Rykaczewska, Bianca E Suur, Samuel Röhl, Anton Razuvaev, Mariette Lengquist, Maria Sabater‐Lleal, +23 more
66citations -
Surface engineering Salmonella with pH‐responsive polyserotonin and self‐activated DNAzyme for better microbial therapy of tumor2023 Exploration article Biochemistry, Genetics and Molecular Biology Cancer Research and Treatments Open access
Lina Guo, Hao Lan Chen, Jinsong Ding, Pengfei Rong, Ming Sun, Wenhu Zhou
36citations -
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation2021 Archives of Toxicology article Biochemistry, Genetics and Molecular Biology Mitochondrial Function and Pathology Open access
Wanda van der Stel, Huan Yang, Nanette G. Vrijenhoek, Johannes P. Schimming, Giulia Callegaro, Giada Carta, +10 more
18citations