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Engineering and application of a biosensor with focused ligand specificity2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Dennis Della Corte, Hugo L. van Beek, Falk Syberg, Marcus Schallmey, Felix Tobola, Kai U. Cormann, +9 more
110citations -
Directed evolution of VanR biosensor specificity in yeast2020 Biotechnology Notes article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Vasil D’Ambrosio, Subrata Pramanik, Kati Goroncy, Tadas Jakočiūnas, David Schönauer, Mehdi D. Davari, +3 more
29citations -
Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells2020 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access cited by 3 patents
Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, +51 more
51citations -
Enhanced Sampling Approach to the Induced-Fit Docking Problem in Protein–Ligand Binding: The Case of Mono-ADP-Ribosylation Hydrolase Inhibitors2021 Journal of Chemical Theory and Computation article Computer Science Computational Drug Discovery Methods Open access
Qianqian Zhao, Riccardo Capelli, Paolo Carloni, Bernhard Lüscher, Jinyu Li, Giulia Rossetti
28citations -
Development of a Biosensor Platform for Phenolic Compounds Using a Transition Ligand Strategy2021 ACS Synthetic Biology article Biochemistry, Genetics and Molecular Biology Microbial Metabolic Engineering and Bioproduction Open access
Lion Konstantin Flachbart, Christoph G. W. Gertzen, Holger Gohlke, Jan Marienhagen
23citations -
Complementary chemical probes and substrates reveal split subsite specificity in a fungal GH12 glucanase2026 ChemRxiv preprint Agricultural and Biological Sciences Polysaccharides and Plant Cell Walls Open access
Thamy L R Corrêa, Nicholas G. S. McGregor, Casper de Boer, Sybrin P. Schröder, Quentin P. O. Foucart, Lianne I. Willems, +4 more
0citations -
Spatial transcriptomics reveals molecular cues underlying the site specificity of the adult mouse oral mucosa and its stem cell niches2024 Stem Cell Reports article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Anna C. Seubert, Marion Krafft, Moutaz Helal, Pranjali Bhandare, Elmar Wolf, Anna Alemany, +2 more
11citations -
Accurate Prediction of GPCR Ligand Binding Affinity with Free Energy Perturbation2020 Journal of Chemical Information and Modeling article Computer Science Computational Drug Discovery Methods cited by 4 patents
Francesca Deflorian, Laura Pérez‐Benito, Eelke Bart Lenselink, Miles Congreve, Herman van Vlijmen, Jonathan S. Mason, +2 more
88citations -
Ligand–Receptor Interactions Elucidate Sex-Specific Pathways in the Trajectory From Primordial Germ Cells to Gonia During Human Development2021 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Open access cited by 1 patent
Arend W. Overeem, Yolanda W. Chang, Jeroen Spruit, Celine M. Roelse, Susana M. Chuva de Sousa Lopes
23citations -
The Versatility of the Dicyanamide Anion (Dca) as a Bridging Ligand: Synthesis, Structure and Theory of a Unique Ladder Chain Consisting of 2 µ1,5-dca Bridged Dinuclear Cu2(dca)2 Units with Additional µ1,3-dca Bridges Along the Chain2024 Journal of Chemical Crystallography article Chemistry Crystal structures of chemical compounds Open access
Yaakoub Saadallah, Zouaoui Setifi, Hela Ferjani, Christopher Glidewell, Christian Jelsch, Fatima Setifi, +3 more
1citations -
CrossTalkeR: analysis and visualization of ligand–receptorne tworks2021 Bioinformatics article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
James Shiniti Nagai, Nils B. Leimkühler, Michael T. Schaub, Rebekka K. Schneider, Ivan G. Costa
58citations -
CrossTalkeR: Analysis and Visualisation of Ligand Receptor Networks2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
James Shiniti Nagai, Nils B. Leimkühler, Michael T. Schaub, Rebekka K. Schneider, Ivan G. Costa
9citations -
Localization and discrimination of GG mismatch in duplex DNA by synthetic ligand-enhanced protein nanopore analysis2024 Nucleic Acids Research article Engineering Nanopore and Nanochannel Transport Studies Open access
Wenping Lyu, Jianji Zhu, Xiaoqin Huang, Mauro Chinappi, Denis Garoli, Cenglin Gui, +1 more
6citations -
Functional analysis of ligand-gated chloride channels in a cnidarian sheds light on the evolution of inhibitory signalling2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroscience and Neuropharmacology Research Open access
Alison G. Cole, Audrey Ortega-Ramírez, Juan D. Montenegro, Mihaela Raycheva, Sabrina Kaul, Michèle Bachmann, +5 more
0citations -
A new model of Notch signaling: Control of Notch receptor cis-inhibition via Notch ligand dimers2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Daipeng Chen, Zary Forghany, Xinxin Liu, Haijiang Wang, Roeland M. H. Merks, David A. Baker
0citations -
Imaging and photodynamic therapy of prostate cancer using a theranostic PSMA-targeting ligand2023 European Journal of Nuclear Medicine and Molecular Imaging article Medicine Photodynamic Therapy Research Studies Open access
Yvonne H. W. Derks, Melline G.M. Schilham, Mark Rijpkema, E. Smeets, Helene I. V. Amatdjais‐Groenen, Annemarie Kip, +10 more
16citations -
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions2022 Journal for ImmunoTherapy of Cancer article Immunology and Microbiology Immunotherapy and Immune Responses Open access
Frank M. Speetjens, Marij J.P. Welters, Marije Slingerland, Mariëtte I.E. van Poelgeest, Peggy J. de Vos van Steenwijk, Inge C.F.M. Roozen, +13 more
39citations -
Phase I trial to determine safety and immunogenicity of amplivant, a synthetic toll-like receptor 2 ligand, conjugated to two HPV16 E6 synthetic long peptides.2021 Journal of Clinical Oncology conference-abstract Immunology and Microbiology Immunotherapy and Immune Responses
Frank M. Speetjens, Marij J.P. Welters, Marije Slingerland, Peggy de Vos van Steenwijk, Inge C.F.M. Roozen, Sanne Boekestijn, +9 more
3citations