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Perspectives-Observer-Transparency -- A Novel Paradigm for Modelling the Human in Human-To-Anything Interaction Based on a Structured Review of the Human Digital Twin2024 arXiv (Cornell University) preprint Computer Science Psychiatry, Mental Health, Neuroscience Open access
Nils Mandischer, Alexander Atanasyan, Michael Schluse, Jürgen Roßmann, Lars Mikelsons
0citations -
Comprehensive Analysis of Human Dendritic Spine Morphology and Density: Exploring Diversity of Human Dendritic Spines2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroscience and Neuropharmacology Research
Kerstin D Schünemann, Roxanne M Hattingh, Matthijs B Verhoog, Danqing Yang, Aniella Bak, Sabrina Peter, +14 more
0citations -
A cross-species spatial transcriptomic atlas of the human and non-human primate basal ganglia2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Madeleine N. Hewitt, Meghan A. Turner, Nelson Johansen, Delissa McMillen, Shu Dan, Mike DeBerardine, +45 more
8citations -
The Human Pancreas Cell Atlas defines a healthy reference framework for disease contextualization and translational benchmarking2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Shrey Parikh, Daniel C. Strobl, Sara Jiménez, Julia Beckmann, Lucas Arnoldt, Eljas Roellin, +18 more
0citations -
Cell Type-Specific and Diabetic Kidney Disease-Associated Expression of Long Non-Coding RNAs in Human Kidneys2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer-related molecular mechanisms research
Juliette A. de Klerk, Roderick C. Slieker, Hao Wu, Yoshiharu Muto, Rudmer J. Postma, Leen M. ‘t Hart, +14 more
0citations -
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR/Cas9 precision genome editing2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 15 patents
Benedetta Artegiani, Delilah F. G. Hendriks, Joep Beumer, Rutger N.U. Kok, Xuan Zheng, Indi P. Joore, +4 more
29citations -
Spatial multi-omic map of human myocardial infarction2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Christoph Kuppe, Ricardo O. Ramirez Flores, Zhijian Li, Monica Toft Hannani, Jovan Tanevski, Maurice Halder, +13 more
78citations -
Human Neocortical Glutamatergic Neurons Revealed Through Multimodal Profiling2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Rachel A. Dalley, Sarah Walling-Bell, Jeremy A. Miller, Femke Waleboer, Julian Thijssen, Audrey McCutcheon, +88 more
3citations -
Genome-wide multi-layered epigenomic profiling across human aging2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access
Mara Steiger, René Krüger, Mina Shaigan, Deepika Puri, Giulia Fornero, Hannes Klump, +4 more
0citations -
Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Atherosclerosis and Cardiovascular Diseases Open access
Tore Bleckwehl, Sidrah Maryam, Anne Babler, Michael Nyberg, Markus Høybye Bosteen, Maurice Halder, +8 more
5citations -
Comparative human embryo-mapping reveals neural bias of neuromesodermal progenitors in stem cell axial elongation models2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Developmental Biology and Gene Regulation Open access
Yuting Wang, Rafaella Buzatu, Cecile Herbermann, Micha Drukker, Christian J. Schröter
0citations -
GRAND: A database of gene regulatory network models across human conditions2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Gene Regulatory Network Analysis Open access
Marouen Ben Guebila, Camila M. Lopes‐Ramos, Deborah A. Weighill, Abhijeet R. Sonawane, Rebekka Burkholz, Behrouz Shamsaei, +4 more
8citations -
Latent plasticity of the human pancreas across development, health, and disease2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Pancreatic function and diabetes Open access
Elisabetta Mereu, Diego Balboa, Johannes Liebig, A. Herrero, Anna Martinez Casals, Mariya Mardamshina, +37 more
5citations -
Survey of the human proteostasis network: the ubiquitin-proteasome system2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ubiquitin and proteasome pathways Open access
Suzanne Elsasser, Evan T. Powers, Thomas Stoeger, Xiaojing Sui, Roy Kurtzbard, Patricia Martínez-Botía, +14 more
6citations -
Lineage-specific microbial protein prediction enables large-scale exploration of protein ecology within the human gut2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genomics and Phylogenetic Studies Open access
Matthias A. Schmitz, Nicholas J Dimonaco, Thomas Clavel, Thomas C. A. Hitch
1citations -
STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 2 patents
Catarina Grandela, Albert Blanch-Asensio, Karina O. Brandão, Tessa de Korte, Loukia Yiangou, Mervyn P.H. Mol, +3 more
1citations -
Post-transcriptional regulatory mechanisms in human islets inferred from cell type-specific eQTLs detected by single-cell RNA-seq2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Twan J. J. de Winter, Miha Sovrovic, Han Sun, James D. Johnson, Patrick Edward MacDonald, Anna L. Gloyn, +3 more
0citations -
Transport-Related Effects on Intrinsic and Synaptic Properties of Human Cortical Neurons: A Comparative Study2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Neuroscience Neuroscience and Neuropharmacology Research Open access
Guanxiao Qi, Danqing Yang, Aniella Bak, Werner Hucko, Daniel Delev, Hussam Aldin Hamou, +2 more
0citations -
KIF23 regulation by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology MicroRNA in disease regulation Open access
Sanchari Roy, Carolin Lohr, Rossella Pellegrino, Mihael Vucur, Michael T. Singer, Veronika Buettner, +7 more
0citations -
A Novel Human Distal Tubuloid-on-a-Chip Model for Investigating Sodium and Water Transport Mechanisms2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Ion Transport and Channel Regulation Open access
M Bernardi, Emre Dilmen, Dorota Kurek, Henriëtte L. Lanz, Jos Joore, Joost G.J. Hoenderop, +2 more
1citations