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Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains2023 Nature Communications article Immunology and Microbiology Complement system in diseases Open access cited by 2 patents
Leoni Abendstein, Douwe J. Dijkstra, Rayman T.N. Tjokrodirijo, Peter A. van Veelen, Leendert Adrianus Trouw, Paul J. Hensbergen, +1 more
50citations -
Probing immune signatures of conjugated pattern recognition receptor ligands identifies chimeras with adjuvant and antitumor activity2025 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immunotherapy and Immune Responses Open access
Špela Janež, Samo Guzelj, Marcela Šišić, Ruža Frkanec, Stane Pajk, Lenny Burgmeijer, +2 more
1citations -
Formulation development of a live attenuated human rotavirus (RV3-BB) vaccine candidate for use in low- and middle-income countries2021 Human Vaccines & Immunotherapeutics article Medicine Viral gastroenteritis research and epidemiology Open access
Prashant Kumar, Ashaben Patel, Swathi R. Pullagurla, Oluwadara Ogun, Ozan S. Kumru, Ahd Hamidi, +5 more
13citations -
Lot-to-lot consistency, immunogenicity, and safety of the Ad26.ZEBOV, MVA-BN-Filo Ebola virus vaccine regimen: A phase 3, randomized, double-blind, placebo-controlled trial2024 Human Vaccines & Immunotherapeutics article Medicine Viral Infections and Outbreaks Research Open access cited by 2 patents
Neil H. Goldstein, Chelsea M. McLean, Auguste Gaddah, Joachim Doua, Babajide Keshinro, Linda Bus-Jacobs, +4 more
8citations -
Safety and immunogenicity of a new Sabin inactivated poliovirus vaccine candidate produced on the PER.C6® cell-line: a phase 1 randomized controlled trial in adults2020 Human Vaccines & Immunotherapeutics article Medicine Viral Infections and Immunology Research Open access
Isabel Leroux‐Roels, Geert G Leroux-Roels, Georgi Shukarev, Hanneke Schuitemaker, Conor P. Cahill, Richard de Rooij, +3 more
8citations -
Immunogenicity and safety of Ad26.RSV.preF/RSV preF protein vaccine at predicted intermediate- and end-of-shelf-life as an evaluation of potency throughout shelf life2024 Human Vaccines & Immunotherapeutics article Medicine Respiratory viral infections research Open access
Tessa Hosman, Roy van Heesbeen, Arangassery Rosemary Bastian, Christy A. Comeaux, Nynke Ligtenberg, Bart van Montfort, +2 more
4citations -
Safety and immunogenicity of 3 formulations of a Sabin inactivated poliovirus vaccine produced on the PER.C6® cell line: A phase 2, double-blind, randomized, controlled study in infants vaccinated at 6, 10 and 14 weeks of age2022 Human Vaccines & Immunotherapeutics article Medicine Viral Infections and Immunology Research Open access
Anna Lisa Ong‐Lim, Georgi Shukarev, Mitzi Trinidad‐Aseron, Delia Caparas-Yu, Astrid E. Greijer, Michel Duchêne, +7 more
4citations -
Safety and immunogenicity of Ad26.COV2.S in adolescents: Phase 2 randomized clinical trial2025 Human Vaccines & Immunotherapeutics article Medicine SARS-CoV-2 and COVID-19 Research Open access
Jelena Tica, Veronica V. Rezelj, Benoît Baron, Vitalija van Paassen, Javier Zaidman, Lee Fairlie, +16 more
3citations -
T-cell responses to SARS-CoV-2 vaccinations in adults with Down syndrome – a prospective cohort study2025 Human Vaccines & Immunotherapeutics article Medicine SARS-CoV-2 and COVID-19 Research Open access
Lobke C.M. Hensen, Bianca M. M. Streng, Femke van Wijk, Stefan Nierkens, Rob S. van Binnendijk, Anne‐Marie Buisman, +14 more
3citations -
Immunogenicity, safety and reactogenicity of Ad26.RSV.preF/RSV preF protein vaccine in adults aged 60 to 75 years: A comparison of phase 2b and phase 3 clinical trial material2024 Human Vaccines & Immunotherapeutics article Medicine Respiratory viral infections research Open access
Archana M. Jastorff, Arangassery Rosemary Bastian, Nynke Ligtenberg, V. G. Klyashtorny, Benoît Callendret, Esther Heijnen
3citations -
Pneumococcal vaccine hyporesponsiveness in people living with HIV: A narrative review of immunological mechanisms and insights from minimally invasive lymph node sampling2025 Human Vaccines & Immunotherapeutics review Medicine Pneumonia and Respiratory Infections Open access
Giovanni E. Loe-Sack-Sioe, Leo G. Visser, Simon P. Jochems, Anna H.E. Roukens
1citations -
T-cell responses to primary SARS-CoV-2 vaccination in Down syndrome – From childhood to adulthood2026 Human Vaccines & Immunotherapeutics article Medicine SARS-CoV-2 and COVID-19 Research Open access
Lobke C.M. Hensen, Bianca M. M. Streng, Femke van Wijk, Stefan Nierkens, Joanne Wildenbeest, Louis Bont, +16 more
0citations -
Repurposing licensed viral vaccines as anti-cancer therapeutics: Turning cold tumors hot2026 Human Vaccines & Immunotherapeutics article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Dorine A. De Bont, Maud Reugebrink, Nadine van Montfoort, Vera Kemp
0citations -
A Bispecific Single-Domain Antibody Boosts Autologous Vγ9Vδ2-T Cell Responses Toward CD1d in Chronic Lymphocytic Leukemia2021 Clinical Cancer Research article Medicine Chronic Lymphocytic Leukemia Research Open access cited by 20 patents
Iris de Weerdt, Roeland Lameris, Jurjen M. Ruben, Renate de Boer, Jan Kloosterman, Lisa A. King, +5 more
62citations -
Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy2025 Journal for ImmunoTherapy of Cancer article Medicine Cancer Immunotherapy and Biomarkers Open access
Ziena Abdulrahman, Roderick C. Slieker, Daniel McGuire, Marij J.P. Welters, Mariëtte I.E. van Poelgeest, Sjoerd H. van der Burg
23citations -
Healthcare Costs of Metastatic Cutaneous Melanoma in the Era of Immunotherapeutic and Targeted Drugs2020 Cancers article Economics, Econometrics and Finance Economic and Financial Impacts of Cancer Open access
Brenda Leeneman, Carin A. Uyl‐de Groot, Maureen J.B. Aarts, Alexander C. J. van Akkooi, Franchette W.P.J. van den Berkmortel, Alfons J.M. van den Eertwegh, +14 more
21citations -
Targeting of the C-Type Lectin Receptor Langerin Using Bifunctional Mannosylated Antigens2020 Frontiers in Cell and Developmental Biology article Immunology and Microbiology Immunotherapy and Immune Responses Open access
R. J. Eveline Li, Tim P. Hogervorst, Silvia Achilli, Sven C. M. Bruijns, Sander W. Spiekstra, Corinne Vivès, +7 more
17citations -
Neutralizing Antibodies Impair the Oncolytic Efficacy of Reovirus but Permit Effective Combination with T cell–Based Immunotherapies2024 Cancer Immunology Research article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Christianne Groeneveldt, Priscilla Kinderman, Lisa Griffioen, Olivia Rensing, Camilla Labrie, Diana J.M. van den Wollenberg, +8 more
8citations -
590 Pre-conditioning of the tumor microenvironment with oncolytic reovirus converts CD3-bispecific antibody treatment into effective immunotherapy2020 Regular and Young Investigator Award Abstracts conference-paper Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Christianne Groeneveldt, Priscilla Kinderman, Diana J.M. van den Wollenberg, Ruben L van den Oever, Jim Middelburg, Dana AM Mustafa, +4 more
3citations -
794 CD163+ macrophages are an effective target for antitumor therapy2025 Regular and Young Investigator Award Abstracts conference-abstract Immunology and Microbiology Immune cells in cancer Open access
Pieter J. Schol, Maarten K. Nijen Twilhaar, Camilla Labrie, Roderick C. Slieker, Jonas Heilskov Graversen, Anders Etzerodt, +2 more
0citations