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Integration of mass cytometry and mass spectrometry imaging for spatially resolved single-cell metabolic profiling2024 Nature Methods article Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Joana B. Nunes, Marieke E. Ijsselsteijn, Tamim Abdelaal, Rick Ursem, Manon van der Ploeg, Martin A. Giera, +4 more
92citations -
Integration of Mass Cytometry and Mass Spectrometry Imaging for Spatially Resolved Single Cell Metabolic Profiling2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Metabolomics and Mass Spectrometry Studies Open access
Joana B. Nunes, Marieke E. Ijsselsteijn, Tamim Abdelaal, Rick Ursem, Manon van der Ploeg, Bart Everts, +3 more
3citations -
An imaging mass cytometry immunophenotyping panel for non-human primate tissues2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Paula Niewold, Marieke E. Ijsselsteijn, Frank A. W. Verreck, Tom H. M. Ottenhoff, Simone A. Joosten
7citations -
Abstract 7196: Detection of radiopharmaceuticals and their cold surrogates by Imaging Mass Cytometry enables assessment of single-cell functional response, therapeutic biodistribution, and modulation of the immune microenvironment
Jennifer L. Gorman, Felix B. Salazar, Kevin Wyszatko, Michael J. Geuenich, Thom G. A. Reuvers, Daniel Majonis, +14 more
0citations -
Batch-effect correction improves downstream imaging mass cytometry data quality and facilitates robust cell type identification in the liver and hepatocellular carcinoma microenvironment2025 Zeitschrift für Gastroenterologie conference-paper Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics
Henrike Salié, Ana Marta Sequeira, Marieke E. Ijsselsteijn, Felix Röttele, Yuan Suo, Lara Wischer, +4 more
0citations -
Semi‐automated background removal limits data loss and normalizes imaging mass cytometry data2021 Cytometry Part A article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 1 patent
Marieke E. Ijsselsteijn, Antonios Somarakis, Boudewijn P. F. Lelieveldt, Thomas Höllt, Noel F.C.C. de Miranda
47citations -
Mapping human natural killer cell development in pediatric tonsil by imaging mass cytometry and high-resolution microscopy2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Immunology and Microbiology Immune Cell Function and Interaction Open access
Everardo Hegewisch-Solloa, Janine E. Melsen, Hiranmayi Ravichandran, André F. Rendeiro, Aharon G. Freud, Bethany L. Mundy-Bosse, +8 more
5citations -
Semi-automated background removal limits loss of data and normalises the images for downstream analysis of imaging mass cytometry data2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Marieke E. Ijsselsteijn, Antonios Somarakis, Boudewijn P. F. Lelieveldt, Thomas Höllt, Noel F.C.C. de Miranda
2citations -
Visualizing the codevelopment of structural and immune cells in the human fetal lung using imaging mass cytometry2025 American Journal of Physiology-Lung Cellular and Molecular Physiology article Medicine Neonatal Respiratory Health Research Open access
Jia Li, Susana M. Chuva de Sousa Lopes, Vincent van Unen, Pieter Sicco Hiemstra, Jan N Stolk, Frits Koning, +1 more
0citations -
Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface2022 iScience article Immunology and Microbiology Reproductive System and Pregnancy Open access cited by 1 patent
Juliette Krop, Anita van der Zwan, Marieke E. Ijsselsteijn, Hanneke Kapsenberg, Sietse J. Luk, Sanne H. Hendriks, +13 more
51citations -
Visualizing the Prevalence and Interactions of Maternal Immune Cells and Fetal Trophoblasts Using Imaging Mass Cytometry: The Prominence of Myeloid Cells2021 SSRN Electronic Journal preprint Immunology and Microbiology Reproductive System and Pregnancy Open access
Juliette Krop, Anita van der Zwan, Marieke E. Ijsselsteijn, Hanneke Kapsenberg, Sietse J. Luk, Sanne H. Hendriks, +13 more
0citations -
A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue2020 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Nannan Guo, Vincent van Unen, Marieke E. Ijsselsteijn, Laura F. Ouboter, Andrea E. van der Meulen‐de Jong, Susana M. Chuva de Sousa Lopes, +3 more
45citations -
High-Dimensional Mass Cytometry Reveals Emphysema-associated Changes in the Pulmonary Immune System2024 American Journal of Respiratory and Critical Care Medicine article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Jia Li, Na Li, Tamim Abdelaal, Nannan Guo, Marieke E. IJsselstein, Vincent van Unen, +8 more
14citations -
Distinct morphological features of malignant cells in large B-cell lymphoma identified by soft-segmentation in imaging-based spatial proteomics2025 Blood conference-abstract Biochemistry, Genetics and Molecular Biology Cell Image Analysis Techniques Open access
Troy Noordenbos, Marieke E. Ijsselsteijn, Noel de Miranda, Joost S.P. Vermaat, Mohammad Shahrokh Esfahani
0citations -
Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease2022 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Vincent van Unen, Laura F. Ouboter, Na Li, Mette Schreurs, Tamim Abdelaal, Yvonne Kooy–Winkelaar, +13 more
33citations -
Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies2020 Frontiers in Oncology article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access cited by 2 patents
Natasja L. De Vries, Ahmed Essam Mahfouz, Frits Koning, Noel F.C.C. de Miranda
60citations