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Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components2020 Gene Therapy article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access cited by 1 patent
Ignazio Maggio, Hidde A. Zittersteijn, Qian Wang, Jin Liu, Josephine M. Janssen, Ivan Toral Ojeda, +4 more
66citations -
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID2020 Molecular Therapy — Methods & Clinical Development article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access cited by 3 patents
Laura García-Pérez, Marja C.J.A. van Eggermond, Lieke van Roon, Sandra A. Vloemans, Martijn Cordes, Axel Schambach, +16 more
58citations -
Generation of four gene-edited human induced pluripotent stem cell lines with mutations in the ATM gene to model Ataxia-Telangiectasia2023 Stem Cell Research article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Wasifa Nurieva, Sanabel Chehab, Parth Singh, Marina Reichlmeir, Károly Szuhai, Georg W. J. Auburger, +2 more
4citations -
Gene deletion and constitutive expression of the pectate lyase gene 1 (MoPL1) lead to diminished virulence of Magnaporthe oryzae2021 The Journal of Microbiology article Biochemistry, Genetics and Molecular Biology Plant Pathogens and Fungal Diseases
Alex Wegner, Florencia Casanova, Marco Loehrer, Angelina Jordine, Stefan Bohnert, Xinyu Liu, +2 more
23citations -
Cancer risks for other sites in addition to breast in CHEK2 c.1100delC families2024 Genetics in Medicine article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Maartje A. C. Schreurs, Marjanka K. Schmidt, Antoinette Hollestelle, Michael Schaapveld, Christi J. van Asperen, Margreet G.E.M. Ausems, +12 more
13citations -
161P Cancer risks for other sites in addition to breast in CHEK2 c.1100delC families2024 ESMO Open article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access
Maartje A. C. Schreurs, Margareta Schmidt, Antoinette Hollestelle, Michael Schaapveld, Christi J. van Asperen, Margreet G.E.M. Ausems, +9 more
0citations -
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs2024 Immunology Letters article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Giorgio Gilioli, Arjan C. Lankester, Sander de Kivit, Frank J. T. Staal, Lisa M. Ott de Bruin
8citations -
RAG1 lentiviral gene therapy restores T-cell development of RAG1-SCID patient cells in artificial thymic organoids2025 Blood Advances article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Janine E. Melsen, Rosalie van der Holst, Bas de Mooij, Sandra A. Vloemans, Marja C.J.A. van Eggermond, Dagmar Berghuis, +7 more
3citations -
Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective2022 Journal of Molecular Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Julian Tristan Schwartze, Menzo J E Havenga, Wilfried A.M. Bakker, Angela C. Bradshaw, Stuart A. Nicklin
39citations -
GeneSurfer enables transcriptome-wide exploration and annotation of gene co-expression modules in 3D spatial transcriptomics data2025 iScience article Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Chang Li, Julian Thijssen, Thomas Kroes, Ximaine R. van der Burg, Louise van der Weerd, Thomas Höllt, +1 more
0citations -
Acquisition of a gene cluster in Clostridioides difficile PCR ribotype 023 strains enables xylitol utilization2026 mSphere article Medicine Clostridium difficile and Clostridium perfringens research Open access
Katherine J. Wozniak, Lei Pan, Duolong Zhu, Jeroen Corver, Ed J. Kuijper, Wiep Klaas Smits, +1 more
0citations -
Gene Therapy of Chronic Limb-Threatening Ischemia: Vascular Medical Perspectives2022 Journal of Clinical Medicine article Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Florian Simon, Mansur Duran, Waseem Garabet, Hubert Schelzig, Michael Johan Jacobs, Alexander Gombert
18citations -
GeneSurfer Enables Transcriptome-wide Exploration and Functional Annotation of Gene Co-expression Modules in 3D Spatial Transcriptomics Data2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Single-cell and spatial transcriptomics Open access
Chang Li, Julian Thijssen, Thomas Kroes, Ximaine R. van der Burg, Louise van der Weerd, Thomas Höllt, +1 more
0citations -
The contribution of tissue-grouped BMI-associated gene sets to cardiometabolic-disease risk: a Mendelian randomization study2020 International Journal of Epidemiology article Biochemistry, Genetics and Molecular Biology Genetic Associations and Epidemiology Open access
Inge Verkouter, Renée de Mutsert, Roelof A. J. Smit, Stella Trompet, Frits Richard Rosendaal, Diana van Heemst, +2 more
14citations -
Human AdV-20-42-42, a promising novel adenoviral vector for gene therapy and vaccine product development2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Virus-based gene therapy research Open access
Mónika Z. Ballmann, Svjetlana Raus, Ruben Engelhart, Győző L. Kaján, Chantal van der Zalm, Tibor Papp, +9 more
1citations -
Molecular analysis of the role of polymerase theta in gene targeting in Arabidopsis thaliana2024 The Plant Journal article Biochemistry, Genetics and Molecular Biology CRISPR and Genetic Engineering Open access
Lejon E. M. Kralemann, Niels van Tol, Paul J. J. Hooykaas, Marcel Tijsterman
4citations