Papers matching “extracellular matrix deposition” 94
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Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Engineering 3D Printing in Biomedical Research Open access
Thomas Geuens, Floor A.A. Ruiter, Anika Schumacher, Francis L. C. Morgan, Timo Rademakers, Loes E. Wiersma, +4 more
1citations -
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix2022 Nature Metabolism article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, Carla Riera‐Domingo, David P. Sumpton, J. Henry M. Däbritz, Saverio Tardito, +22 more
174citations -
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, David P. Sumpton, Claudia Boldrini, Juan Ramon Hernandez-Fernaud, Sandeep Dhayade, +18 more
6citations -
Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix2022 Nature Metabolism erratum Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, Carla Riera‐Domingo, David P. Sumpton, J. Henry M. Däbritz, Saverio Tardito, +22 more
4citations -
Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition2021 Biomaterials article Engineering 3D Printing in Biomedical Research Open access cited by 1 patent
Thomas Geuens, Floor A.A. Ruiter, Anika Schumacher, Francis L. C. Morgan, Timo Rademakers, Loes E. Wiersma, +4 more
72citations -
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis2020 Respiratory Research article Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Open access cited by 1 patent
Sarah Rank Rønnow, Rand Qais Dabbagh, Federica Genovese, Carmel B. Nanthakumar, Vikki Barrett, Robert B. Good, +7 more
48citations -
Extracellular Matrix and Endothelial Activation Markers in the Bronchial and Pulmonary Arteries in COPD2025 The Clinical Respiratory Journal article Medicine Chronic Obstructive Pulmonary Disease (COPD) Research Open access
Raquel Annoni, Jôse Mára de Brito, Natália de Souza Xavier Costa, Ligia Couceiro, Renata Calciolari Rossi, Marisa Dolhnikoff, +4 more
1citations -
Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix2025 Advanced Functional Materials article Engineering Bone Tissue Engineering Materials Open access
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia J. T. Roumans, Christian Plank, Christopher H. Evans, Fergal J. O’Brien, +2 more
2citations -
Human cardiomyocyte derived extracellular vesicles regulate cardiac fibroblast activation through miR-242024 Cardiovascular Research article Biochemistry, Genetics and Molecular Biology Extracellular vesicles in disease Open access
G Senesi, Alessandra Maria Lodrini, S A Mohammed, Simone Mosole, Davide Ceresa, Sara Bolis, +6 more
3citations -
3D Humanized Bioprinted Tubulointerstitium Model to Emulate Renal Fibrosis In Vitro2024 Advanced Healthcare Materials article Engineering 3D Printing in Biomedical Research Open access
Gabriele Addario, Julia Fernández‐Pérez, Chiara Formica, Konstantinos Karyniotakis, Lea Herkens, Sonja Djudjaj, +3 more
18citations -
Intercellular interaction between FAP+ fibroblasts and CD150+ inflammatory monocytes mediates fibrostenosis in Crohn’s disease2024 Journal of Clinical Investigation article Biochemistry, Genetics and Molecular Biology Inflammatory Bowel Disease Open access
Bo-Jun Ke, Saeed Abdurahiman, Francesca Biscu, Gaia Zanella, Gabriele Dragoni, Sneha Santhosh, +22 more
50citations -
Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression2024 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Chronic Kidney Disease and Diabetes Open access
Nadine Tuechler, Mira Lea Burtscher, Martín Garrido‐Rodríguez, Muzamil Majid Khan, Dénes Türei, Christian Tischer, +8 more
0citations -
Dynamic suspension culture enhances scalable maturation of hiPSC-derived cartilage organoids for regenerative medicine2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Tissue Engineering and Regenerative Medicine Open access
Giorgia Mazzini, Evelyn Houtman, Marcella van Hoolwerff, Merel L. Janssen, Sayedeh Sana Sayedipour, Ghazaleh Hajmousa, +4 more
0citations -
Understanding the use of spheroids and pellets in the chondrogenic differentiation of human stem cells2026 Osteoarthritis and Cartilage Open article Medicine Osteoarthritis Treatment and Mechanisms Open access
Donna-Madina A.J. Sangen, Stefan Giselbrecht, Martijn van Griensven, Steven Vermeulen, Elizabeth Rosado Balmayor
0citations -
Evaluating the Role of AMB-05X in Modulating Key Fibrotic Markers in Human Precision-cut Lung Slices2025 American Journal of Respiratory and Critical Care Medicine conference-abstract Medicine Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Christina Hesse, Valerie Beneke, Lena Willmer, Kerstin N. Schmidt, Jan Fiedler, Danny David Jonigk, +3 more
0citations -
Inhibition of mitochondrial complex I by rotenone reduces arterial calcification in vitro2026 Biochemical and Biophysical Research Communications article Medicine Alkaline Phosphatase Research Studies Open access
Theo G. M. F. Gorgels, Tabea Köneke, Setareh Karimian, Julia Moellmann, Heidi Noels, Nikolaus Marx, +1 more
0citations