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Cancer, Hypoxia, and Metabolism Sign in to save
Papers per year
Papers 30
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PHGDH heterogeneity potentiates cancer cell dissemination and metastasis2022 Nature article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, +45 more
223citations -
A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer2020 eLife article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access cited by 2 patents
Haojie Jin, Siying Wang, Esther A. Zaal, Cun Wang, Hai-Qiu Wu, Astrid R. Bosma, +8 more
185citations -
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix2022 Nature Metabolism article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, Carla Riera‐Domingo, David P. Sumpton, J. Henry M. Däbritz, Saverio Tardito, +22 more
174citations -
Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression2022 Nature Communications article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Marco Sciacovelli, Aurélien J. F. Dugourd, Lorea Valcárcel-Jiménez, Ming Hui Yang, Efterpi Nikitopoulou, Ana S.H. Costa, +22 more
65citations -
Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I2021 Cell chemical biology article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Shashi Jain, Cheng Hu, Jérôme Kluza, Mădălina Giurgiu, Andreas Bleilevens, Alexandre Rosa Campos, +10 more
61citations -
Hypoxia PET Imaging with [18F]-HX4—A Promising Next-Generation Tracer2020 Cancers article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access cited by 2 patents
Sebastian Sanduleanu, Alexander M. A. van der Wiel, Relinde I. Y. Lieverse, Damiënne Marcus, Abdalla Ibrahim, Sergey P. Primakov, +5 more
54citations -
Acute vs. chronic vs. intermittent hypoxia in breast Cancer: a review on its application in in vitro research2022 Molecular Biology Reports article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Qiuyu Liu, Victoria A. C. Palmgren, Erik H.J. Danen, Sylvia E. Le Dévédec
40citations -
Circumventing the Crabtree effect in cell culture: A systematic review2021 Mitochondrion review Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Michèle J.C. de Kok, Alexander F. Schaapherder, Rob C. I. Wüst, Melissa C. Zuiderwijk, Jaap Adriaan Bakker, Jan H.N. Lindeman, +1 more
31citations -
Metabolic reprogramming related to whole-chromosome instability in models for Hürthle cell carcinoma2020 Scientific Reports article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Ruben D. Addie, Sarantos Kostidis, Willem E. Corver, Jan Oosting, Sepideh Aminzadeh-Gohari, René G. Feichtinger, +4 more
20citations -
Effect of Esomeprazole Treatment on Extracellular Tumor pH in a Preclinical Model of Prostate Cancer by MRI-CEST Tumor pH Imaging2022 Metabolites article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Pietro Irrera, Miriam Roberto, Lorena Consolino, Annasofia Anemone, Daisy Villano, Victor Navarro‐Tableros, +4 more
13citations -
Hypoxia and activation of hypoxia inducible factor alpha as influencers of inflammatory helper T cells in autoimmune disease – a link between cancer and autoimmunity2025 Frontiers in Immunology article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Giovanni Almanzar, Ruth Garzón, Ana M. Navarro, Alejandro O. Ondo-Mendez, Martina Prelog
12citations -
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis2022 Nature erratum Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Matteo Rossi, Patricia Altea‐Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fukano, +45 more
8citations -
PYCR1-dependent proline synthesis in cancer-associated fibroblasts is required for the deposition of pro-tumorigenic extracellular matrix2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Emily Jane Kay, Karla Paterson, David P. Sumpton, Claudia Boldrini, Juan Ramon Hernandez-Fernaud, Sandeep Dhayade, +18 more
6citations -
Metabolomic and Lipidomic Analysis of the Colorectal Adenocarcinoma Cell Line HT29 in Hypoxia and Reoxygenation2023 Metabolites article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Juan Carlos Alarcón Barrera, Alejandro O. Ondo-Mendez, Martin A. Giera, Sarantos Kostidis
6citations -
Nitrogen partitioning between branched-chain amino acids and urea cycle enzymes sustains renal cancer progression2021 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Marco Sciacovelli, Aurélien J. F. Dugourd, Lorea Valcárcel-Jiménez, Ming Hui Yang, Efterpi Nikitopoulou, Ana S.H. Costa, +22 more
5citations -
Histone lactylation-driven feedback loop modulates pyrimidine metabolism to promote oral carcinogenesis2026 Cell Death and Disease article Biochemistry, Genetics and Molecular Biology Cancer, Hypoxia, and Metabolism Open access
Yanting Wang, Yanlin Geng, Yannan Chen, Haowen Zhang, Jingyu Liu, Yulin Song, +3 more
5citations
Most active Aachen authors
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Julio Sáez-Rodríguez 48,113 citations overall5 papers
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Sylvia E. Le Dévédec 3,049 citations overall5 papers
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Erik H.J. Danen 9,611 citations overall4 papers
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Enio Gjerga 749 citations overall3 papers
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Manfred Wuhrer 32,864 citations overall2 papers
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Peter A. van Veelen 18,468 citations overall2 papers
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Rafael Kramann 16,535 citations overall2 papers
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Bob van de Water 13,491 citations overall2 papers
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Martin A. Giera 13,167 citations overall2 papers
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Thorsten Cramer 11,543 citations overall2 papers
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Tao Zhang 7,464 citations overall2 papers
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Christoph Kuppe 6,383 citations overall2 papers
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Aurélien J. F. Dugourd 5,639 citations overall2 papers
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Sarantos Kostidis 3,645 citations overall2 papers
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Hai-Qiu Wu 1,122 citations overall2 papers